scholarly journals SLC25A24as a Novel Susceptibility Gene for Low Fat Mass in Humans and Mice

2015 ◽  
Vol 100 (4) ◽  
pp. E655-E663 ◽  
Author(s):  
Tomohiko Urano ◽  
Masataka Shiraki ◽  
Noriko Sasaki ◽  
Yasuyoshi Ouchi ◽  
Satoshi Inoue
Keyword(s):  
Fat Mass ◽  
Susceptibility Gene ◽  
Low Fat

scholarly journals Effects of Ad Libitum Low Carbohydrate Versus Low Fat Diets on Body Weight and Fat Mass

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 658-658
Author(s):  
Alex Schick ◽  
James Boring ◽  
Amber Courville ◽  
Isabelle Gallagher ◽  
Juen Guo ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Body Fat ◽  
Fat Mass ◽  
Kidney Diseases ◽  
Primary Study ◽  
Low Fat ◽  
Fat Loss ◽  
Low Carbohydrate ◽  
Ad Libitum

Abstract Objectives To describe the effects of ad libitum low-fat (LF) and low-carbohydrate (LC) diets on body weight and fat mass. Methods Sixteen adults without diabetes spent 29 continuous days residing at the Metabolic Clinical Research Unit of the NIH Clinical Center where they were fed ad libitum either an animal-based, LC diet (75% fat, 10% carbohydrates, 15% protein) or a plant-based, LF diet (75% carbohydrates, 10% fat, 15% protein). Participants were randomly assigned to one diet for the first phase of the study (14 days), after which they were switched to the other diet for the remainder of the study. Participants were given three meals daily and were provided with additional snacks amounting to 200% of their daily energy requirements as determined by their resting energy expenditure multiplied by 1.6. Subjects were told that this was not a weight loss study and were not informed about the primary study aim. They were instructed to eat as much or as little as they desired. Total body weight and fat mass were measured using a calibrated scale and dual-energy X-ray absorptiometry, respectively. Subjects were blinded to their data and wore loose-fitting scrubs to avoid any feedback regarding changes in the fit of their clothing. Results Subjects included 7 women and 9 men, with an age of (mean ± SE) 29 ± 1.7 years and BMI of 27.5 ± 1.5 at baseline. Participants lost weight on both diets, with the LC diet resulting in 1.34 ± 0.31 kg of weight loss (P = 0.0006) and the LF diet resulting in 1.09 ± 0.31 kg of weight loss (P = 0.003) which was not significantly different from the LC diet (P = 0.58). However, participants lost 0.6 ± 0.17 kg of body fat on the LF diet (P = 0.002) but the LC diet did not result in significant body fat loss (0.04 ± 0.17 kg; P = 0.8) and the difference in body fat loss between the diets was statistically significant (P = 0.03). Conclusions While participants lost similar amounts of weight on both diets, only the LF diet led to significant body fat loss. Early weight loss with a LC diet does not necessarily reflect a similar state of negative energy balance as compared with a LF diet. Funding Sources Intramural Research Program of the National Institutes of Diabetes and Digestive and Kidney Diseases.

scholarly journals Is inflammation the missing link between low fat mass and low survival in hemodialysis patients?

2006 ◽  
Vol 70 (10) ◽  
pp. 1881 ◽  
Author(s):  
G. Tsirpanlis ◽  
S. Chatzipanagiotou ◽  
F. Boufidou ◽  
V. Kordinas ◽  
F. Alevyzaki ◽  
...  
Keyword(s):  
Fat Mass ◽  
Hemodialysis Patients ◽  
Low Fat ◽  
Missing Link

scholarly journals Higher intakes of low‐fat milk combined with 12 weeks of endurance training does not result in lower fat mass and higher lean mass.

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Rebekah Roberts ◽  
Elizabeth Euiler ◽  
Wendy Ward ◽  
Paul LeBlanc ◽  
Mark Tarnopolsky ◽  
...  
Keyword(s):  
Endurance Training ◽  
Fat Mass ◽  
Lean Mass ◽  
Low Fat

scholarly journals Adult-onset deletion of the Prader-Willi syndrome susceptibility gene Snord116 in mice results in reduced feeding and increased fat mass

2017 ◽  
Vol 6 (2) ◽  
pp. 88-97 ◽  
Author(s):  
Louise Purtell ◽  
Yue Qi ◽  
Lesley Campbell ◽  
Amanda Sainsbury ◽  
Herbert Herzog
Keyword(s):  
Fat Mass ◽  
Susceptibility Gene ◽  
Prader Willi Syndrome ◽  
Adult Onset

Hormonal Response to Weight Gain in a Male with Low Fat Mass, Relative Under-Nutrition and Over-Training

2011 ◽  
pp. P3-226-P3-226
Author(s):  
Nicola M Neary ◽  
Amber B Courville ◽  
Samantha Smith ◽  
Gail R Hall ◽  
Kong Y Chen ◽  
...  
Keyword(s):  
Weight Gain ◽  
Fat Mass ◽  
Hormonal Response ◽  
Low Fat ◽  
Under Nutrition

scholarly journals Restricting Calories on Low-Carbohydrate vs Low-fat Diets for Weight Loss: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1609-1609
Author(s):  
Anthony Basile ◽  
Michael Renner ◽  
Jessica Scillian ◽  
Karen Sweazea
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Mass Loss ◽  
Fat Mass ◽  
Meta Analysis ◽  
Low Fat ◽  
Fat Loss ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate ◽  
Fat Mass Loss

Abstract Objectives As the never-ending macronutrient debate for weight loss continues, conflicting evidence persist. Per the carbohydrate-insulin hypothesis, a low-carbohydrate diet (LC) should produce a greater weight/fat loss compared to a low-fat/calorie diet (LF) by releasing less of the anabolic hormone insulin. However, from a ‘calories in, calories out’ perspective, does restricting calories on a LC diet produce a greater weight/fat loss compared to a LF diet? Methods A systematic review and meta-analysis of LC vs LF trials for weight loss was conducted and data were collected from 53 studies. Weight loss data were converted to kcals (1 kg = 3500 kcals) and a ratio was produced for each individual diet (ID-Ratio: weight loss in kcals/restricted dietary kcals) where a ratio of 1 indicates that one dietary kcal restriction equals one kcal of weight loss. Next, to compare the two diets, a comparison ratio (DC-Ratio: LC ID-Ration/LF ID-Ratio) was produced where a ratio greater than 1 indicates greater weight loss per dietary calorie restricted with LC diet. These calculations were repeated for body fat loss for full duration (n = 30 trials) and time of greatest weight loss (TGWL; Weight Loss: n = 19 trials; Fat Mass Loss: n = 4 trials). Results LC diets produced a greater weight loss (Full Duration: 6.10 kg vs 4.86 kg; n = 53 trials; P = 0.024; TGWL: 6.29 kg vs 4.34 kg; n = 19 trials; P = 0.024), however no difference was found for the amount of restricted calories or fat mass loss for either duration. No difference was found for the LC and LF ID-Ratios for weight or fat mass loss for either duration. The mean weight loss DC-Ratio was greater than 1 (Full Duration Mean: 1.61, SD: 1.71, n = 53 studies, P = 0.004; TGWL Mean: 1.74, SD: 1.0, n = 19 trails, P = 0.010) indicating a greater weight loss per calorie restricted with a LC diet. However, the fat loss DC-Ratio was not different from 1 (Full Duration Mean: 1.74, SD: 1.09, n = 30 trials, P = 0.552; TGWL Mean: 1.25, SD: 0.53, n = 4 trials, P = 0.428). Conclusions From a ‘calories in, calories out’ perspective, restricting calories on a LC diet produced a greater weight loss for the full duration of the trails and at the time of greatest weight loss compared to a LF diet. As no effect was seen on LC diets and fat mass loss, these results do not support the carbohydrate-insulin hypothesis of obesity. Funding Sources School of Life Sciences, Arizona State University.

Fructo-oligosaccharides reduce energy intake but do not affect adiposity in rats fed a low-fat diet but increase energy intake and reduce fat mass in rats fed a high-fat diet

2017 ◽  
Vol 182 ◽  
pp. 114-120 ◽  
Author(s):  
Zouheyr Hadri ◽  
Rojo Rasoamanana ◽  
Gilles Fromentin ◽  
Dalila Azzout-Marniche ◽  
Patrick C. Even ◽  
...  
Keyword(s):  
Energy Intake ◽  
Fat Mass ◽  
High Fat Diet ◽  
High Fat ◽  
Low Fat ◽  
Low Fat Diet ◽  
Increase Energy Intake ◽  
Reduce Energy Intake
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