scholarly journals Fatty Acyl Esterification and Deesterification of 17β-Estradiol in Human Breast Subcutaneous Adipose Tissue

2012 ◽  
Vol 97 (9) ◽  
pp. 3349-3356 ◽  
Author(s):  
Feng Wang ◽  
Veera Vihma ◽  
Maija Badeau ◽  
Hanna Savolainen-Peltonen ◽  
Marjut Leidenius ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Fatty Acyl ◽  
Human Breast ◽  
17Β Estradiol ◽  
Subcutaneous Adipose

Estradiol effects on subcutaneous adipose tissue lipolysis in premenopausal women are adipose tissue depot specific and treatment dependent

2013 ◽  
Vol 304 (11) ◽  
pp. E1167-E1174 ◽  
Author(s):  
Kathleen M. Gavin ◽  
Elizabeth E. Cooper ◽  
Dustin K. Raymer ◽  
Robert C. Hickner
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Premenopausal Women ◽  
Submaximal Exercise ◽  
Rest Perfusion ◽  
Adrenergic Antagonist ◽  
17Β Estradiol ◽  
Regional Adiposity ◽  
Subcutaneous Adipose

Estrogen has direct effects within adipose tissue and has been implicated in regional adiposity; however, the influence of estrogen on in vivo lipolysis is unclear. The purpose of this study was to investigate the effect of local 17β-estradiol (E2) on subcutaneous adipose tissue (SAT) lipolysis in premenopausal women. In vivo lipolysis (dialysate glycerol) was measured in 17 women (age 27.4 ± 2.0 yr, BMI 29.7 ± 0.5 kg/m2) via microdialysis of abdominal (AB) and gluteal (GL) SAT. Glycerol was measured at baseline and during acute interventions to increase lipolysis including local perfusion of isoproterenol (ISO, β-adrenergic agonist, 1.0 μmol/l), phentolamine (PHEN, α-adrenergic antagonist, 0.1 mmol/l), and submaximal exercise (60% V̇o2peak, 30 min); all with and without coperfusion of E2(500 nmol/l). E2coperfusion blunted the lipolytic response to ISO in AB (E2196 ± 31%, control 258 ± 26%, P = 0.003) but not in GL (E2113 ± 14%, control 111 ± 12%, P = 0.43) adipose tissue. At rest, perfusion of PHEN with ISO did not change dialysate glycerol. Submaximal exercise during ISO + PHEN increased dialysate glycerol in the AB (56 ± 9%) and GL (62 ± 12%) regions. Probes perfused with E2during exercise and ISO + PHEN had an increased lipolytic response in AB (90 ± 9%, P = 0.007) but a lower response in GL (35 ± 7%, P = 0.05) SAT compared with no-E2conditions. E2effects on lipolysis are region specific and may work through both adrenergic and adrenergic-independent mechanisms to potentiate and/or blunt SAT lipolysis in premenopausal women.

Identification of Estrogen Receptor β RNA in Human Breast and Abdominal Subcutaneous Adipose Tissue

1998 ◽  
Vol 248 (3) ◽  
pp. 523-526 ◽  
Author(s):  
David L. Crandall ◽  
Dennis E. Busler ◽  
Thomas J. Novak ◽  
Renata V. Weber ◽  
John G. Kral
Keyword(s):  
Estrogen Receptor ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Estrogen Receptor Β ◽  
Human Breast ◽  
Subcutaneous Adipose

Insulin resistance, systemic and regional inflammation in subcutaneous adipose tissue during weight loss in a population with obesity

2019 ◽  
Author(s):  
Frederique Van de Velde ◽  
Margriet Ouwens ◽  
Arsene-Helene Batens ◽  
Samyah Shadid ◽  
Bruno Lapauw ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Weight Loss ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Subcutaneous Adipose

701-P: Effects of Exercise on Extracellular Matrix Modifiers in Subcutaneous Adipose Tissue of Obese Adults

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 701-P
Author(s):  
PALLAVI VARSHNEY ◽  
BENJAMIN J. RYAN ◽  
CHIWOON AHN ◽  
MICHAEL W. SCHLEH ◽  
JEFFREY F. HOROWITZ
Keyword(s):  
Extracellular Matrix ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Obese Adults ◽  
Subcutaneous Adipose

scholarly journals Atypical expression of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in subcutaneous adipose tissue of male rats

1999 ◽  
Vol 40 (6) ◽  
pp. 1071-1077
Author(s):  
Stéphane Thumelin ◽  
Claude Kohl ◽  
Jean Girard ◽  
Jean-Paul Pégorier
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Male Rats ◽  
Subcutaneous Adipose
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