scholarly journals Thyroid-Stimulating Hormone Levels within the Reference Range Are Associated with Serum Lipid Profiles Independent of Thyroid Hormones

2012 ◽  
Vol 97 (8) ◽  
pp. 2724-2731 ◽  
Author(s):  
Furong Wang ◽  
Yinyin Tan ◽  
Chenggang Wang ◽  
Xu Zhang ◽  
Yuanfei Zhao ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Serum Lipid ◽  
Reference Range ◽  
Thyroid Stimulating Hormone ◽  
Lipid Profiles ◽  
Hormone Levels ◽  
Stimulating Hormone

scholarly journals Seizure duration may increase thyroid-stimulating hormone levels in children experiencing a seizure

2019 ◽  
Vol 48 (5) ◽  
pp. 030006051988840
Author(s):  
Ji Yoon Han ◽  
In Goo Lee ◽  
Soyoung Shin ◽  
Joonhong Park
Keyword(s):  
Thyroid Hormones ◽  
Neuronal Excitability ◽  
Thyroid Stimulating Hormone ◽  
Seizure Type ◽  
Hormonal Changes ◽  
Seizure Duration ◽  
Hormone Levels ◽  
Logistic Regression Models ◽  
Tsh Levels ◽  
Stimulating Hormone

Objective Variations in hormone levels are a direct effect of epileptic discharges in both animals and humans, and seizure can affect the hypothalamus–pituitary–thyroid axis. The purpose of this study was to determine which parameters could affect the alternation of thyroid hormones in children experiencing seizure. Methods We retrospectively reviewed the medical records of 181 pediatric patients with seizure and compared three thyroid hormones (serum thyroid-stimulating hormone [TSH], free thyroxine [fT4], and triiodothyronine [T3]) between initial (admission to hospital) and follow-up (2 weeks later) testing. Results Multivariable logistic regression models were used to determine which six parameters (gender, age, seizure accompanying with fever, seizure type, seizure duration, and anti-epileptic drug medication) could help to explain the higher initial TSH levels in pediatric seizure. Only seizure duration in patients with an increase in TSH levels was significantly longer compared with patients with normal TSH at the time of initial testing. Conclusion Neuronal excitability by seizure can cause thyroid hormonal changes, which likely reflects changes in hypothalamic function.

scholarly journals The study of pituitary-thyroid hormones ratio based on regression analysis

2015 ◽  
Vol 96 (5) ◽  
pp. 831-837
Author(s):  
F Kh Kamilov ◽  
V N Kozlov ◽  
V N Baymatov ◽  
A N Mamtsev ◽  
D Yu Smirnov
Keyword(s):  
Body Weight ◽  
Regression Analysis ◽  
Thyroid Hormones ◽  
Least Squares ◽  
Least Squares Method ◽  
Thyroid Stimulating Hormone ◽  
Hormone Levels ◽  
Relationship Of ◽  
The Relationship ◽  
Stimulating Hormone

Aim. To work up a mathematical model for calculation of the levels of pituitary-thyroid hormones system by least squares method in rats with experimental hypothyroidism. Methods. To study the relationship of hormones levels regression analysis was used. The search of coefficients was performed using the least squares method. Investigations were carried out on rats, which were divided into six groups of 12 rats each: the first group was control, in the animals of second, third, fourth, fifth and sixth groups hypothyroidism was induced by daily intragastric administration of tiamazol in following doses: 2.5; 20.0; 10.0; 5.0 and 1.0 mg per 100 g of rat body weight for 3 weeks. Results. Regression analysis was carried out, the type of regression as well as parameters were chosen; statistical analysis of the relationship of hormones was conducted based on the obtained results. By comparing the calculation results of the laboratory analysis sufficiently high reliability of the developed model was set up. The deviation of the arithmetic mean value of the level of thyroid stimulating hormone, produced on the basis of experimental and calculated data, is 2.7%. The accuracy of thyroid stimulating hormone levels calculations increased with the decrease of thyrostatic medication dose. The relative error while calculating the free thyroxine levels in the same groups of rats did not exceed 2.15%, accounting for 1.64; 1.34; 0.36 and 2.15%, respectively, when administered daily 20.0; 10.0; 5.0 and 1.0 mg of antithyroid drug per 100 g body weight. One can argue about the reliability of the constructed model to reproduce the performance levels of the hormones of the pituitary-thyroid system. Conclusion. In the absence of modern high sensitive immunochemiluminescent diagnostic methods the results can be used for thyroid-stimulating hormone levels calculation as one of the major markers of the thyroid gland functional state.

Establishment of Early Pregnancy Related Thyroid Hormone Models and Reference Intervals for Pregnant Women in China Based on Real World Data

2021 ◽  
Vol 53 (04) ◽  
pp. 272-279
Author(s):  
Chaochao Ma ◽  
Xiaoqi Li ◽  
Lixin Liu ◽  
Xinqi Cheng ◽  
Fang Xue ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Hormones ◽  
Pregnant Women ◽  
Early Pregnancy ◽  
Gestational Age ◽  
Dynamic Change ◽  
Reference Intervals ◽  
Thyroid Stimulating Hormone ◽  
Free Thyroxine ◽  
Stimulating Hormone

AbstractThyroid hormone reference intervals are crucial for diagnosing and monitoring thyroid dysfunction during early pregnancy, and the dynamic change trend of thyroid hormones during pregnancy can assist clinicians to assess the thyroid function of pregnant women. This study aims to establish early pregnancy related thyroid hormones models and reference intervals for pregnant women. We established two derived databases: derived database* and derived database#. Reference individuals in database* were used to establish gestational age-specific reference intervals for thyroid hormones and early pregnancy related thyroid hormones models for pregnant women. Individuals in database# were apparently healthy non-pregnant women. The thyroid hormones levels of individuals in database# were compared with that of individuals in database* using nonparametric methods and the comparative confidence interval method. The differences in thyroid stimulating hormone and free thyroxine between early pregnant and non-pregnant women were statistically significant (p<0.0001). The reference intervals of thyroid stimulating hormone, free thyroxine and free triiodothyronine for early pregnant women were 0.052–3.393 μIU/ml, 1.01–1.54 ng/dl, and 2.51–3.66 pg/ml, respectively. Results concerning thyroid stimulating hormone and free thyroxine reference intervals of early pregnancy are comparable with those from other studies using the same detection platform. Early pregnancy related thyroid hormones models showed various change patterns with gestational age for thyroid hormones. Early pregnancy related thyroid hormones models and reference intervals for pregnant women were established, so as to provide accurate and reliable reference basis for the diagnosing and monitoring of maternal thyroid disfunction in early pregnancy.

Increase in thyroid stimulating hormone levels in patients with gout treated with inhibitors of xanthine oxidoreductase

2015 ◽  
Vol 35 (11) ◽  
pp. 1857-1861 ◽  
Author(s):  
Fernando Perez-Ruiz ◽  
Sandra Pamela Chinchilla ◽  
Joana Atxotegi ◽  
Irati Urionagüena ◽  
Ana Maria Herrero-Beites ◽  
...  
Keyword(s):  
Thyroid Stimulating Hormone ◽  
Xanthine Oxidoreductase ◽  
Hormone Levels ◽  
Stimulating Hormone

scholarly journals Normalization of thyroid stimulating hormone levels in acromegalic patients after selective adenomectomy.

1984 ◽  
Vol 31 (6) ◽  
pp. 687-695 ◽  
Author(s):  
HIROYASU TSUCHIYA ◽  
TOSHIO ONISHI ◽  
SHINTARO MORI ◽  
SHOUSHI LEE ◽  
HIROSHI KOHNO ◽  
...  
Keyword(s):  
Thyroid Stimulating Hormone ◽  
Hormone Levels ◽  
Stimulating Hormone
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