scholarly journals A Stimulatory Thyrotropin Receptor Antibody Enhances Hyaluronic Acid Synthesis in Graves' Orbital Fibroblasts: Inhibition by an IGF-I Receptor Blocking Antibody

2012 ◽  
Vol 97 (5) ◽  
pp. 1681-1687 ◽  
Author(s):  
Seema Kumar ◽  
Seethalakshmi Iyer ◽  
Hilary Bauer ◽  
Michael Coenen ◽  
Rebecca S. Bahn
Keyword(s):  
Hyaluronic Acid ◽  
Acid Synthesis ◽  
Thyrotropin Receptor ◽  
Blocking Antibody ◽  
Receptor Blocking ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody ◽  
Igf I ◽  
Orbital Fibroblasts

Identification of two different phenotypes of patients with amiodarone-induced thyrotoxicosis and positive thyrotropin receptor antibody tests

Thyroid ◽  
2021 ◽  
Author(s):  
Daniele Cappellani ◽  
Giuseppina De Marco ◽  
Eleonora Ferrarini ◽  
Liborio Torregrossa ◽  
Agostino Maria Di Certo ◽  
...  
Keyword(s):  
Thyrotropin Receptor ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody ◽  
Antibody Tests

Thyrotropin receptor antibody: A novel risk indicator for pregnancy loss

2019 ◽  
Vol 64 ◽  
pp. 44-48 ◽  
Author(s):  
Yuyan Li ◽  
Ting Xu ◽  
Qinyun Mo ◽  
Weiling Fu ◽  
Chunyan Yao
Keyword(s):  
Pregnancy Loss ◽  
Risk Indicator ◽  
Thyrotropin Receptor ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody

scholarly journals Pathogenetic Role of Thyrotropin Receptor Antibody in the Development of Hyperthyroidism Following Primary Hypothyroidism

1989 ◽  
Vol 4 (2) ◽  
pp. 118-125 ◽  
Author(s):  
Young Kee Shong ◽  
Bo Youn Cho ◽  
Sung Kwan Hong ◽  
Hong Kyu Lee ◽  
Chang Soon Koh ◽  
...  
Keyword(s):  
Primary Hypothyroidism ◽  
Thyrotropin Receptor ◽  
Pathogenetic Role ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody

scholarly journals Preserved activation of thyrotropin receptor antibody to stimulate thyroid function despite long-term treatment in euthyroid patients with Graves' disease

1998 ◽  
pp. 281-285 ◽  
Author(s):  
M Akuzawa ◽  
M Murakami ◽  
M Yamada ◽  
T Satoh ◽  
H Shimizu ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Normal Subjects ◽  
Term Treatment ◽  
Graves Disease ◽  
Thyrotropin Receptor ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody ◽  
Long Term Treatment ◽  
Tsh Levels

Clinical evaluation was conducted to ascertain whether thyrotropin receptor antibody (TRAb) in the normal range may still be involved in the regulation of thyroid function after prolonged treatment for Graves' disease. All patients (n = 33) were treated with antithyroid drugs for an average of 10.6 years and were under euthyroid conditions in which normal blood levels of tri-iodothyronine (T3) were significantly correlated with blood thyrotropin (TSH) levels, but not with titers of TRAb. A significant correlation was observed between TRAb titer and thyroid-stimulating antibody (TSAb) activity. In contrast, this correlation was not found in normal subjects. After administration of T3 (75 microg daily for 8 days), the patients showed increased levels of T3 with concomitant suppression of TSH levels. Under these conditions, linear regression analysis showed significant correlations of TRAb titer and TSAb activity with 24-h thyroid radioiodine uptake (r = 0.641 and 0.621 respectively, P < 0.01), in contrast to declining blood thyroxine levels. Moreover, the immunoglobulin G (IgG) of the patients precipitated to a greater extent than IgG from normal subjects a peptide consisting of the amino acid sequence near the terminus of the human TSH receptor. These findings indicated that TRAb at normal levels possessed significant unremitting activities on thyroid function despite long-term treatment in euthyroid patients with Graves' disease.

Amiodarone-Induced Thyrotoxicosis Associated with Thyrotropin Receptor Antibody

Thyroid ◽  
1998 ◽  
Vol 8 (12) ◽  
pp. 1123-1126 ◽  
Author(s):  
KANJI SATO ◽  
KAZUKO YAMAZAKI ◽  
YOSHIO KANAJI ◽  
SATOSHI OHNISHI ◽  
HIROSHI KASANUKI ◽  
...  
Keyword(s):  
Thyrotropin Receptor ◽  
Receptor Antibody ◽  
Thyrotropin Receptor Antibody
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