scholarly journals Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline

2011 ◽  
Vol 96 (7) ◽  
pp. 1911-1930 ◽  
Author(s):  
Michael F. Holick ◽  
Neil C. Binkley ◽  
Heike A. Bischoff-Ferrari ◽  
Catherine M. Gordon ◽  
David A. Hanley ◽  
...  
Keyword(s):  
Vitamin D ◽  
Clinical Practice ◽  
Vitamin D Deficiency ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Endocrine Society ◽  
Treatment And Prevention

scholarly journals Response to Letter: “Pediatric Obesity—Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline”

2017 ◽  
Vol 102 (6) ◽  
pp. 2123-2124 ◽  
Author(s):  
Dennis M. Styne ◽  
Silva A. Arslanian ◽  
Ellen L. Connor ◽  
Ismaa Sadaf Farooqi ◽  
M. Hassan Murad ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Pediatric Obesity ◽  
Endocrine Society ◽  
Treatment And Prevention

scholarly journals Vitamin D dose response is underestimated by Endocrine Society's Clinical Practice Guideline

2013 ◽  
Vol 2 (2) ◽  
pp. 87-95 ◽  
Author(s):  
Malachi J McKenna ◽  
Barbara F Murray
Keyword(s):  
Vitamin D ◽  
Clinical Practice ◽  
Rate Constant ◽  
Dose Response ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Institute Of Medicine ◽  
Endocrine Society ◽  
The Mean ◽  
The Difference

ObjectiveThe recommended daily intakes of vitamin D according to the recent Clinical Practice Guideline (CPG) of the Endocrine Society are three- to fivefold higher than the Institute of Medicine (IOM) report. We speculated that these differences could be explained by different mathematical approaches to the vitamin D dose response.MethodsStudies were selected if the daily dose was ≤2000 IU/day, the duration exceeded 3 months, and 25-hydroxyvitamin D (25OHD) concentrations were measured at baseline and post-therapy. The rate constant was estimated according to the CPG approach. The achieved 25OHD result was estimated according to the following: i) the regression equation approach of the IOM; ii) the regression approach of the Vitamin D Supplementation in Older Subjects (ViDOS) study; and iii) the CPG approach using a rate constant of 2.5 (CPG2.5) and a rate constant of 5.0 (CPG5.0). The difference between the expected and the observed 25OHD result was expressed as a percentage of observed and analyzed for significance against a value of 0% for the four groups.ResultsForty-one studies were analyzed. The mean (95% CI) rate constant was 5.3 (4.4–6.2) nmol/l per 100 IU per day, on average twofold higher than the CPG rate constant. The mean (95% CI) for the difference between the expected and observed expressed as a percentage of observed was as follows: i) IOM, −7 (−16,+2)% (t=1.64, P=0.110); ii) ViDOS, +2 (−8,+12)% (t=0.40, P=0.69); iii) CPG2.5, −21 (−27,−15)% (t=7.2, P<0.0001); and iv) CPG5.0+3 (−4,+10)% (t=0.91, P=0.366).ConclusionThe CPG ‘rule of thumb’ should be doubled to 5.0 nmol/l (2.0 ng/ml) per 100 IU per day, adopting a more risk-averse position.

JCEM ARCHIVEOsteoporosis in Men: An Endocrine Society Clinical Practice Guideline

2013 ◽  
pp. 179-209
Author(s):  
Nelson B. Watts ◽  
Robert A. Adler ◽  
John P. Bilezikian ◽  
Matthew T. Drake ◽  
Richard Eastell ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Endocrine Society
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