scholarly journals Increased Melatonin and Delayed Offset in Menopausal Depression: Role of Years Past Menopause, Follicle-Stimulating Hormone, Sleep End Time, and Body Mass Index

2008 ◽  
Vol 93 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Barbara L. Parry ◽  
Charles J. Meliska ◽  
Diane L. Sorenson ◽  
Ana M. López ◽  
Luis F. Martínez ◽  
...  
1996 ◽  
Vol 10 (1) ◽  
pp. 17-21 ◽  
Author(s):  
F. Zullo ◽  
C. Di Carlo ◽  
M. Pellicano ◽  
C. Catizone ◽  
P. Mastrantonio ◽  
...  

2004 ◽  
Vol 21 (12) ◽  
pp. 431-436 ◽  
Author(s):  
Kathrin Ferlitsch ◽  
Michael O. Sator ◽  
Doris M. Gruber ◽  
Ernst R�cklinger ◽  
Christian J. Gruber ◽  
...  

Author(s):  
Jin Wang ◽  
Ting Yao ◽  
Xinxin Zhang ◽  
Qi Chen ◽  
Shuo Gong ◽  
...  

Background This study aimed to establish anti-Mullerian hormone age-specific reference intervals and determine the correlation between the anti-Mullerian hormone concentration and age, body mass index and concentrations of follicle-stimulating hormones and luteinizing hormone in healthy Chinese girls. Methods Serum anti-Mullerian hormone concentrations of 1702 healthy girls (0−12 years), recruited between March 2018 and December 2019, were determined using the Beckman Access 2 automated chemiluminescence immunoassay. Single-year-specific medians of anti-Mullerian hormone and effects of age, body mass index, follicle-stimulating hormone and luteinizing hormone on anti-Mullerian hormone concentration were analysed. Results The anti-Mullerian hormone median level continued increasing from birth, reached its peak at age 9 at 4.45 ng/mL (interquartile range [IQR] 2.58–6.90) and then gradually decreased. At age 12, the median reached 1.98 ng/mL (IQR 1.05–3.46). Age-specific reference intervals for anti-Mullerian hormone were established in healthy Chinese girls aged 0–12 years. Anti-Mullerian hormone concentrations showed a moderately positive correlation with age (r = 0.33, P < 0.001). In contrast, follicle-stimulating hormone (r = –0.29, P < 0.001) concentrations were weakly negatively correlated with the serum anti-Mullerian hormone concentration. Conclusion We established single-year-specific reference intervals for anti-Mullerian hormone in Chinese girls using the Beckman chemiluminescent platform. This reference range can help clinicians accurately understand anti-Mullerian hormone secretion in healthy girls and promote its clinical use.


1991 ◽  
Vol 125 (3) ◽  
pp. 280-285 ◽  
Author(s):  
J. Alan Talbot ◽  
Ann Lambert ◽  
Robert Mitchell ◽  
Marek Grabinski ◽  
David C. Anderson ◽  
...  

Abstract We have investigated the role of Ca2+ in the control of FSH-induced estradiol secretion by Sertoli cells isolated from 8-10 days old rats. Exogenous Ca2+ (4-8 mmol/1) inhibited FSH-stimulated E2 secretion such that, with 8 mmol/l Ca2+ and FSH (8 IU/l) E2 secretion decreased from 2091±322 to 1480±84 pmol/l (p<0.002), whilst chelation of Ca2+ in the culture medium with EGTA (3 mmol/l) increased E2 secretion from 360±45 to 1242±133 pmol/l) in the absence of FSH. Further, EGTA (3 mmol/l) markedly potentiated FSH (8 IU/l), forskolin (1 μmol/l) and dibutyryl cAMP (1 mmol/l)-stimulated E2 secretion. Addition of the Ca2+ ionophores, ionomycin (2-5 μmol/l) and A23187 (2 μmol/l), inhibited FSH (8 IU/l)-stimulated E2 secretion by >80%. The effect of ionomycin was totally reversible, whereas that of A23187 was irreversible. Ionomycin (5 μmol/l) had no effect on EGTA-induced E2 secretion in the absence of FSH, but reduced EGTA-provoked E2 secretion by 59% in the presence of FSH (8 IU/l). Similarly, forskolin- and dibutyryl cAMP-provoked E2 production was inhibited 46-50% by ionomycin (5 μmol/l). We conclude that FSH-induced E2 secretion from immature rat Sertoli cells is modulated by intra- and extracellular Ca2+.


2018 ◽  
Vol 69 (7) ◽  
pp. 1842-1845
Author(s):  
Lavinia Stelea ◽  
Izabella Petre ◽  
Marius Craina ◽  
Brigitha Vlaicu ◽  
Alina Sisu ◽  
...  

The aim of this study was to determine if body mass can be considered a risk factor for infertility, and if we can find any correlations between the age values and the FSH and estradiol values, and between the BMI values and the FSH and estradiol values. Our whole sample contains 100 patients splinted in two groups (pregnant patients N1=57 subjects, 57%, and not � pregnant patients N1=43 subjects,43%). In the first part we conducted our analysis on the whole group and after that we focused the analysis on the two groups and we made some comparisons between the groups. We obtained a medium, extremely significant correlation in all scenarios between the age and the FSH values. This is the best association from all the cases which we tested. In all twelve cases we have a positive correlation (r ] 0). As well, we obtained that a BMI value higher than 25can be considered a risk factor for obtaining a pregnancy (p[0.05, RR ] 1, OR]1) . Our study shows that women who have weight problems have much less chances of conceiving a baby, even if they ovulate normally. The risk of infertility increases proportionally to the extra pounds. Irregular ovulation in women is the most common fertility disorder due to obesity disease.


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