scholarly journals Gonadotropin-Releasing Hormone Neurons Express Estrogen Receptor-β

2007 ◽  
Vol 92 (7) ◽  
pp. 2827-2830 ◽  
Author(s):  
E. Hrabovszky ◽  
I. Kalló ◽  
N. Szlávik ◽  
É. Keller ◽  
I. Merchenthaler ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Estrogen Receptor Β ◽  
Releasing Hormone ◽  
Express Estrogen Receptor

scholarly journals Ligand-Independent Effects of Estrogen Receptor β on Mouse Gonadotropin-Releasing Hormone Promoter Activity

Endocrinology ◽  
2006 ◽  
Vol 147 (4) ◽  
pp. 1924-1931 ◽  
Author(s):  
Toni R. Pak ◽  
Wilson C. J. Chung ◽  
James L. Roberts ◽  
Robert J. Handa
Keyword(s):  
Estrogen Receptor ◽  
Promoter Activity ◽  
Gonadotropin Releasing Hormone ◽  
Estrogen Receptor Β ◽  
Releasing Hormone ◽  
Independent Effects

scholarly journals Estrogen Receptor β Mediates Rapid Estrogen Actions on Gonadotropin-Releasing Hormone NeuronsIn Vivo

2003 ◽  
Vol 23 (13) ◽  
pp. 5771-5777 ◽  
Author(s):  
István M. Ábrahám ◽  
Seong-Kyu Han ◽  
Martin G. Todman ◽  
Kenneth S. Korach ◽  
Allan E. Herbison
Keyword(s):  
Estrogen Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Estrogen Receptor Β ◽  
Releasing Hormone

scholarly journals Estrogen Receptor-β Immunoreactivity in Luteinizing Hormone-Releasing Hormone Neurons of the Rat Brain

Endocrinology ◽  
2001 ◽  
Vol 142 (7) ◽  
pp. 3261-3264 ◽  
Author(s):  
Erik Hrabovszky ◽  
Annamária Steinhauser ◽  
Klaudia Barabás ◽  
Paul J. Shughrue ◽  
Sandra L. Petersen ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Luteinizing Hormone ◽  
Rat Brain ◽  
Estrogen Receptor Β ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone

scholarly journals Prenatal LHRH Neurons in Nasal Explant Cultures Express Estrogen Receptor β Transcript

Endocrinology ◽  
2002 ◽  
Vol 143 (7) ◽  
pp. 2503-2507 ◽  
Author(s):  
Neda Sharifi ◽  
Andree E. Reuss ◽  
Susan Wray
Keyword(s):  
Central Nervous System ◽  
Estrogen Receptor ◽  
Sex Steroids ◽  
Estrogen Receptor Β ◽  
Reproductive State ◽  
Specific Primers ◽  
Explant Cultures ◽  
The Central Nervous System ◽  
Express Estrogen Receptor

Abstract Sex steroids influence LHRH neuronal activity, exerting a negative or positive feedback action, depending on the reproductive state of the animal. Recent evidence indicates that LHRH neurons possess the estrogen receptor β (ERβ) subtype postnatally, suggesting that estrogen may act, in part, directly on LHRH neurons. In this study, we identified ERβ transcript in prenatal LHRH neurons as a function of age. Single-cell cDNA pools were made from LHRH neurons maintained for 7, 14, and 28 d in vitro (div). Screening of the cDNA pools by PCR with ERβ-specific primers revealed ERβ-positive LHRH neurons at all three ages. However, the number of LHRH cells coexpressing ERβ transcript decreased dramatically between 14 (6/10) and 28 div (1/10). None of the LHRH cells were positive for ERα transcript. These results indicate that developing LHRH neurons express the transcript for ERβ and suggest that continued expression of ERβ is either a characteristic of LHRH neurons that may require cues from the central nervous system and/or periphery or predetermined to be maintained in a subpopulation of LHRH neurons.

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