scholarly journals Glucose and Lipid Metabolism in Small-for-Gestational-Age Infants at 72 Hours of Age

2006 ◽  
Vol 92 (2) ◽  
pp. 681-684 ◽  
Author(s):  
Xinli Wang ◽  
Yunpu Cui ◽  
Xiaomei Tong ◽  
Hongmao Ye ◽  
Song Li
Keyword(s):  
Lipid Metabolism ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Glucose And Lipid Metabolism

Glucose and Lipid Metabolism in Small For Gestational Age Infants at 48 Hours of Age

PEDIATRICS ◽  
2003 ◽  
Vol 111 (4) ◽  
pp. 804-809 ◽  
Author(s):  
R. A. Bazaes ◽  
T. E. Salazar ◽  
E. Pittaluga ◽  
V. Pena ◽  
A. Alegria ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Glucose And Lipid Metabolism

scholarly journals Metabolic implications of GH treatment in small for gestational age

2007 ◽  
Vol 157 (suppl_1) ◽  
pp. S47-S50 ◽  
Author(s):  
E M Delemarre ◽  
J Rotteveel ◽  
H A Delemarre-van de Waal
Keyword(s):  
Lipid Metabolism ◽  
Gestational Age ◽  
Growth Retardation ◽  
Small For Gestational Age ◽  
Postnatal Growth ◽  
Gh Treatment ◽  
Increased Risk ◽  
Igf I

Fetal growth retardation is associated with decreased postnatal growth, resulting in a lower adult height. In addition, a low birth weight is associated with an increased risk of developing diseases during adulthood, such as insulin resistance, type 2 diabetes mellitus, hypertension, dyslipidemia, and cardiovascular diseases. Children with persistent postnatal growth retardation, i.e., incomplete catchup growth, can be treated with human GH. The GH/IGF-I axis is involved in the regulation of carbohydrate and lipid metabolism. The question of whether treatment with GH in children born small for gestational age (SGA) has long-term implications with respect to glucose/insulin and lipid metabolism has not been answered yet. In this article, the available data are reviewed.

scholarly journals Lipid metabolism is altered in maternal, placental, and fetal tissues of ewes with small for gestational age fetuses†

2020 ◽  
Author(s):  
Chelsie B Steinhauser ◽  
Katharine Askelson ◽  
Colleen A Lambo ◽  
Kenneth C Hobbs ◽  
Fuller W Bazer ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Bile Acids ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
National Research Council ◽  
Allantoic Fluid ◽  
Fetal Weight ◽  
Placental Development ◽  
Sheep Model ◽  
Blood Concentrations

Abstract Nutrient restriction (NR) has the potential to negatively impact birthweight, an indicator of neonatal survival and lifelong health. Those fetuses are termed as small for gestational age (SGA). Interestingly, there is a spectral phenotype of fetal growth rates in response to NR associated with changes in placental development, nutrient and waste transport, and lipid metabolism. A sheep model with a maternal diet, starting at Day 35, of 100% National Research Council (NRC) nutrient requirements (n = 8) or 50% NRC (n = 28) was used to assess alterations in fetuses designated NR SGA (n = 7) or NR NonSGA (n = 7) based on fetal weight at Day 135 of pregnancy. Allantoic fluid concentrations of triglycerides were greater in NR SGA fetuses than 100% NRC and NR NonSGA fetuses at Day 70 (P < 0.05). There was a negative correlation between allantoic fluid concentrations of triglycerides (R2 = 0.207) and bile acids (R2 = 0.179) on Day 70 and fetal weight at Day 135 for NR ewes (P < 0.05). Bile acids were more abundant in maternal and fetal blood for NR SGA compared to 100% NRC and NR NonSGA ewes (P < 0.05). Maternal blood concentrations of NEFAs increased in late pregnancy in NR NonSGA compared to NR SGA ewes (P < 0.05). Protein expression of fatty acid transporter SLC27A6 localized to placentomal maternal and fetal epithelia and decreased in Day 70 NR SGA compared to 100% NRC and NR NonSGA placentomes (P < 0.05). These results identify novel factors associated with an ability of placentae and fetuses in NR NonSGA ewes to adapt to, and overcome, nutritional hardship during pregnancy.

scholarly journals 379 Lipid Metabolism in Small for Gestational Age Infants at Birth and After 72 H of Age

2010 ◽  
Vol 68 ◽  
pp. 195-196
Author(s):  
S J Milenkovic ◽  
T Nikolic ◽  
N Ristovski ◽  
M Stankovic
Keyword(s):  
Lipid Metabolism ◽  
Gestational Age ◽  
Small For Gestational Age
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