scholarly journals Branched-chain Amino Acid Catabolism by Brown Adipose Tissue

Endocrinology ◽  
2020 ◽  
Vol 161 (7) ◽  
Author(s):  
André C Carpentier
Keyword(s):  
Adipose Tissue ◽  
Amino Acid ◽  
Brown Adipose Tissue ◽  
Amino Acid Catabolism ◽  
Branched Chain Amino Acid ◽  
Brown Adipose ◽  
Branched Chain

scholarly journals Correlation of Plasma Amino Acid and Anthropometric Profiles with Brown Adipose Tissue Density in Humans

2021 ◽  
Vol 10 (11) ◽  
pp. 2339
Author(s):  
Miyuki Kuroiwa ◽  
Sayuri Hamaoka-Fuse ◽  
Masahiro Sugimoto ◽  
Yuko Kurosawa ◽  
Yasuko Aita ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Amino Acid ◽  
Brown Adipose Tissue ◽  
Near Infrared ◽  
Winter Season ◽  
Plasma Amino Acid ◽  
Anthropometric Parameters ◽  
Tissue Density ◽  
Brown Adipose ◽  
Branched Chain

This study examined the relationship between plasma amino acid (AA) concentrations, including branched-chain AAs, and brown adipose tissue density (BAT-d). One hundred and seventy-three subjects (69 men, 104 women) aged 22–68 years were recruited during the winter season. AAs were comprehensively quantified using liquid chromatography-time-of-flight-mass spectrometry. The total hemoglobin concentration in the supraclavicular region ([total-Hb]sup), an indicator of BAT-d, was assessed using near-infrared time-resolved spectroscopy. Anthropometric parameters, including age, percentage of body fat, and visceral fat, were evaluated. Factors associated with higher (≥74 µM) or lower (<74 µM) [total-Hb]sup were investigated by multiple logistic regression models that included AA concentrations alone (model 1) or AA concentrations and anthropometric parameters (model 2) as independent variables. When adjusted for the false discovery rate, [total-Hb]sup was positively correlated with glycine and asparagine levels in men and with the serine level in both men and women and was negatively correlated with the branched-chain AA concentration in men. Models 1 and 2 correlated with higher or lower BAT-d for men (r = 0.73, p = 0.015) and women (r = 0.58, p = 0.079) and for men (r = 0.82, p = 0.0070) and women (r = 0.70, p = 0.020), respectively. A combination of anthropometric parameters and plasma AA concentrations could be a reliable biomarker for higher and lower BAT-d.

scholarly journals Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Ieva Antanavičiūtė ◽  
Valeryia Mikalayeva ◽  
Ieva Ceslevičienė ◽  
Gintarė Milašiūtė ◽  
Vytenis Arvydas Skeberdis ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Amino Acid Catabolism ◽  
Hallmarks Of Cancer ◽  
Branched Chain Amino Acid ◽  
Branched Chain

scholarly journals Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels

2010 ◽  
Vol 285 (15) ◽  
pp. 11348-11356 ◽  
Author(s):  
Mark A. Herman ◽  
Pengxiang She ◽  
Odile D. Peroni ◽  
Christopher J. Lynch ◽  
Barbara B. Kahn
Keyword(s):  
Adipose Tissue ◽  
Amino Acid ◽  
Branched Chain Amino Acid ◽  
Branched Chain
Sign in / Sign up

Export Citation Format

Share Document