Interleukin-2 induces corticotropin-releasing hormone release from superfused rat hypothalami: influence of glucocorticoids

Endocrinology ◽  
1992 ◽  
Vol 131 (2) ◽  
pp. 677-683 ◽  
Author(s):  
J. C. Cambronero
Keyword(s):  
Interleukin 2 ◽  
Hormone Release ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Ethanol Modulates Corticotropin Releasing Hormone Release From the Rat Hypothalamus: Does Acetaldehyde Play a Role?

2010 ◽  
Vol 34 (4) ◽  
pp. 588-593 ◽  
Author(s):  
Carla Cannizzaro ◽  
Marco La Barbera ◽  
Fulvio Plescia ◽  
Silvana Cacace ◽  
Giuseppe Tringali
Keyword(s):  
Hormone Release ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Rat Hypothalamus

A Short Negative Feedback Mechanism Regulating Corticotropin-Releasing Hormone Release*

1987 ◽  
Vol 64 (5) ◽  
pp. 909-913 ◽  
Author(s):  
TOSHIHIRO SUDA ◽  
NAOKI TOMORI ◽  
FUMIKO YAJIMA ◽  
TSUYAKO USHIYAMA ◽  
TAKASHI SUMITOMO ◽  
...  
Keyword(s):  
Negative Feedback ◽  
Feedback Mechanism ◽  
Hormone Release ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Negative Feedback Mechanism

C-type natriuretic peptide exerts stimulatory effects on the corticotropin-releasing hormone-induced secretion of hormones in normal man

1997 ◽  
Vol 136 (4) ◽  
pp. 388-393 ◽  
Author(s):  
Michael Kellner ◽  
Ines Diehl ◽  
Kristina Knaudt ◽  
Cornelius Schüle ◽  
Holger Jahn ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Area Under Curve ◽  
Statistical Significance ◽  
Subjective Effects ◽  
Endocrine Regulation ◽  
Hormone Release ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Atrial Natriuretic

Abstract C-type natriuretic peptide and atrial natriuretic peptide have been reported to bind to distinct receptors and to exert opposing effects on different systems. Although it is known that atrial natriuretic peptide inhibits the corticotropin-releasing hormone-stimulated hormone release in man, the corresponding action of C-type natriuretic peptide has so far not been characterized. We investigated the effects of 30-min infusions of 150 and 300 μg C-type natriuretic peptide on adrenocorticotropin, cortisol, and prolactin release stimulated by 100 μg corticotropin-releasing hormone and on cardiovascular parameters in 8 healthy male volunteers. Compared with placebo, 300 μg C-type natriuretic peptide significantly (P<0·05) enhanced the stimulation of cortisol (area under curve (arbitrary units): 520 ± 35 vs 651 ± 55) and prolactin (area under curve: 29 ± 3 vs 37 ± 5). Adrenocorticotropin levels were increased, but the differences did not reach statistical significance (maximum increment: 27±4 vs 36± 2 pg/ml). C-type natriuretic peptide at a dose of 150 μg had no clear effect on these hormones and C-type natriuretic peptide also produced no cardiovascular or subjective effects. Our data suggest stimulatory effects of C-type natriuretic peptide on corticotropinreleasing hormone-induced hormone release and offer further evidence for a complex role of different natriuretic peptides in endocrine regulation. European Journal of Endocrinology 136 388–393

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