scholarly journals The effect of drug concentration and curing time on processing and properties of calcium alginate beads containing metronidazole by response surface methodology

2006 ◽  
Vol 7 (4) ◽  
pp. E24-E30 ◽  
Author(s):  
Yagnesh L. Patel ◽  
Praveen Sher ◽  
Atmaram P. Pawar
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Drug Concentration ◽  
Calcium Alginate ◽  
Alginate Beads ◽  
Curing Time ◽  
Calcium Alginate Beads

Optimization of calcium alginate beads production by electrospray using response surface methodology

2019 ◽  
Vol 6 (9) ◽  
pp. 095412
Author(s):  
Mozhgan Zakeri ◽  
Hamid Moghadam ◽  
Aabdolreza Samimi ◽  
Davod Mohebbi-Kalhori
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Calcium Alginate ◽  
Alginate Beads ◽  
Calcium Alginate Beads

scholarly journals Development and evaluation of calcium alginate beads prepared by sequential and simultaneous methods

2010 ◽  
Vol 46 (4) ◽  
pp. 785-793 ◽  
Author(s):  
Sanchita Mandal ◽  
S. Senthil Kumar ◽  
Balakrishnam Krishnamoorthy ◽  
Sanat Kumar Basu
Keyword(s):  
Drug Concentration ◽  
Calcium Alginate ◽  
Drug Loading ◽  
Polymer Concentration ◽  
Crosslinking Agent ◽  
Amorphous State ◽  
Alginate Beads ◽  
Aqueous Environment ◽  
Sequential Method ◽  
Calcium Alginate Beads

The objective of this study was to develop a sustained release dosage form of Trimetazidine dihydrochloride (TMZ) using a natural polymeric carrier prepared in a completely aqueous environment. TMZ was entrapped in calcium alginate beads prepared with sodium alginate by the ionotropic gelation method using calcium chloride as a crosslinking agent. The drug was incorporated either into preformed calcium alginate gel beads (sequential method) or incorporated simultaneously during the gelation stage (simultaneous method). The beads were evaluated for particle size and surface morphology using optical microscopy and SEM, respectively. Beads produced by the sequential method had higher drug entrapment. Drug entrapment in the sequential method was higher with increased CaCl2 and polymer concentration but lower with increased drug concentration. In the simultaneous method, drug entrapment was higher when polymer and drug concentration were increased and also rose to a certain extent with increase in CaCl2 concentration, where further increase resulted in lower drug loading. FTIR studies revealed that there is no interaction between drug and CaCl2. XRD studies showed that the crystalline drug changed to an amorphous state after formulation. Release characteristics of the TMZ loaded calcium alginate beads were studied in enzyme-free simulated gastric and intestinal fluid.

scholarly journals The Enzymatic Decolorization of Textile Dyes by the Immobilized Polyphenol Oxidase from Quince Leaves

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Gulnur Arabaci ◽  
Ayse Usluoglu
Keyword(s):  
Polyphenol Oxidase ◽  
Calcium Alginate ◽  
Enzyme Stability ◽  
Industrial Effluent ◽  
Alginate Beads ◽  
Textile Dyes ◽  
Kinetic Properties ◽  
Synthetic Dyes ◽  
Cydonia Oblonga ◽  
Calcium Alginate Beads

Water pollution due to release of industrial wastewater has already become a serious problem in almost every industry using dyes to color its products. In this work, polyphenol oxidase enzyme from quince (Cydonia Oblonga) leaves immobilized on calcium alginate beads was used for the successful and effective decolorization of textile industrial effluent. Polyphenol oxidase (PPO) enzyme was extracted from quince (Cydonia Oblonga) leaves and immobilized on calcium alginate beads. The kinetic properties of free and immobilized PPO were determined. Quince leaf PPO enzyme stability was increased after immobilization. The immobilized and free enzymes were employed for the decolorization of textile dyes. The dye solutions were prepared in the concentration of 100 mg/L in distilled water and incubated with free and immobilized quince (Cydonia Oblonga) leaf PPO for one hour. The percent decolorization was calculated by taking untreated dye solution. Immobilized PPO was significantly more effective in decolorizing the dyes as compared to free enzyme. Our results showed that the immobilized quince leaf PPO enzyme could be efficiently used for the removal of synthetic dyes from industrial effluents.

scholarly journals Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153685 ◽  
Author(s):  
Shen-Fu Lin ◽  
Ying-Chen Chen ◽  
Ray-Neng Chen ◽  
Ling-Chun Chen ◽  
Hsiu-O Ho ◽  
...  
Keyword(s):  
Calcium Alginate ◽  
Alginate Beads ◽  
Calcium Alginate Beads ◽  
The Stability

Calcium alginate beads motion in a foaming three-phase bubble column

2017 ◽  
Vol 324 ◽  
pp. 358-369 ◽  
Author(s):  
Gabriel Salierno ◽  
Mauricio Maestri ◽  
Stella Piovano ◽  
Miryan Cassanello ◽  
María Angélica Cardona ◽  
...  
Keyword(s):  
Calcium Alginate ◽  
Bubble Column ◽  
Alginate Beads ◽  
Calcium Alginate Beads ◽  
Three Phase
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