scholarly journals Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis

AAPS PharmSci ◽  
2002 ◽  
Vol 4 (4) ◽  
pp. 68-79 ◽  
Author(s):  
Ulrika Wählby ◽  
E. Niclas Jonsson ◽  
Mats O. Karlsson
Keyword(s):  
Model Building ◽  
Population Pharmacokinetic ◽  
Covariate Model ◽  
Pharmacodynamic Analysis ◽  
Covariate Model Building

The use of clinical irrelevance criteria in covariate model building with application to dofetilide pharmacokinetic data

2008 ◽  
Vol 35 (5) ◽  
pp. 503-526 ◽  
Author(s):  
Karin Tunblad ◽  
Lars Lindbom ◽  
Lynn McFadyen ◽  
E. Niclas Jonsson ◽  
Scott Marshall ◽  
...  
Keyword(s):  
Model Building ◽  
Pharmacokinetic Data ◽  
Covariate Model ◽  
Covariate Model Building

Adjusted adaptive Lasso for covariate model-building in nonlinear mixed-effect pharmacokinetic models

2017 ◽  
Vol 44 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Elham Haem ◽  
Kajsa Harling ◽  
Seyyed Mohammad Taghi Ayatollahi ◽  
Najaf Zare ◽  
Mats O. Karlsson
Keyword(s):  
Model Building ◽  
Adaptive Lasso ◽  
Pharmacokinetic Models ◽  
Mixed Effect ◽  
Covariate Model ◽  
Nonlinear Mixed Effect ◽  
Covariate Model Building

Choosing the Allometric Exponent in Covariate Model Building

2018 ◽  
Vol 58 (1) ◽  
pp. 89-100 ◽  
Author(s):  
Jaydeep Sinha ◽  
Hesham S. Al-Sallami ◽  
Stephen B. Duffull
Keyword(s):  
Model Building ◽  
Allometric Exponent ◽  
Covariate Model ◽  
Covariate Model Building
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