scholarly journals Pharmacodynamic parameter estimation: Population size versus number of samples

2005 ◽  
Vol 7 (2) ◽  
pp. E461-E466 ◽  
Author(s):  
Suzette Girgis ◽  
Sudhakar M. Pai ◽  
Ihab G. Girgis ◽  
Vijay K. Batra
2021 ◽  
Vol 19 (2) ◽  
pp. 1128-1153
Author(s):  
Junhua Ku ◽  
◽  
Shuijia Li ◽  
Wenyin Gong ◽  

<abstract><p>The accuracy of unknown parameters determines the accuracy of photovoltaic (PV) models that occupy an important position in the PV power generation system. Due to the complexity of the equation equivalent of PV models, estimating the parameters of the PV model is still an arduous task. In order to accurately and reliably estimate the unknown parameters in PV models, in this paper, an enhanced Rao-1 algorithm is proposed. The main point of enhancement lies in i) a repaired evolution operator is presented; ii) to prevent the Rao-1 algorithm from falling into a local optimum, a new evolution operator is developed; iii) in order to enable population size to change adaptively with the evolutionary process, the population size linear reduction strategy is employed. To verify the validity of ERao-1 algorithm, we embark a study on parameter estimation of three different PV models. Experimental results show that the proposed ERao-1 algorithm performs better than existing parameter estimation algorithms in terms of the accuracy and reliability, especially for the double diode model with RMSE 9.8248E-04, three diode model with RMSE 9.8257E-04 for the R.T.C France silicon cell, and 2.4251E-03 for the three diode model of Photowatt- PWP201 cell. In addition, the fitting curve of the simulated data and the measured data also shows the accuracy of the estimated parameters.</p></abstract>


Author(s):  
S. M. Ivanov

The article deals with analytical solution and adaptation to the parameter estimation of the SIR model of the epidemic. By a special replacement of the exponential function by inverse proportionality, the approximate general solution of the SIR model is found. It is spoken in detail about the process of integration of ordinary differential equations of the SIR model. The equality of the sum of the obtained analytical solutions and population size is checked. The obtained solutions are simple and understandable. To parametrically estimate the SIR model, its general solution is adapted to paired linear regressions. The article is of interest for students, graduate students and scientists involved in mathematical epidemiology.


Author(s):  
Delbert E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
T. Fast ◽  
J. Stevenson ◽  
...  

Space Lab 3 (SL-3) was flown on Shuttle Challenger providing an opportunity to measure the effect of spaceflight on rat testes. Cannon developed the idea that organisms react to unfavorable conditions with highly integrated metabolic activities. Selye summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Many papers have been published showing the effects of social interaction, crowding, peck order and confinement. Flickinger showed delayed testicular development in subordinate roosters influenced by group numbers, social rank and social status. Christian reported increasing population size in mice resulted in adrenal hypertrophy, inhibition of reproductive maturation and loss of reproductive function in adults. Sex organ weights also declined. Two male dogs were flown on Cosmos 110 for 22 days. Fedorova reported an increase of 30 to 70% atypical spermatozoa consisting of tail curling and/or the absence of a tail.


Optimization ◽  
1976 ◽  
Vol 7 (5) ◽  
pp. 665-672
Author(s):  
H. Burke ◽  
C. Hennig ◽  
W H. Schmidt

2019 ◽  
Vol 24 (4) ◽  
pp. 492-515 ◽  
Author(s):  
Ken Kelley ◽  
Francis Bilson Darku ◽  
Bhargab Chattopadhyay

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