The Effect of Mixing on the Metastable Zone Width and Nucleation Kinetics in the Anti-Solvent Crystallization of Benzoic Acid

2007 ◽  
Vol 85 (7) ◽  
pp. 945-952 ◽  
Author(s):  
D. O’Grady ◽  
M. Barrett ◽  
E. Casey ◽  
B. Glennon
2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Abdelali Borji ◽  
Fatima-Ezzahra Borji ◽  
Abdelaziz Jourani

Using the spectrophotometric method, as a new method, the influence of dextran on the sucrose solubility and metastable zone width has been studied. In agreement with the literature the experimental data show that the dextran has a negligible effect on the sucrose solubility. The results also show that this impurity decreases the sucrose metastable zone width. The study of the nucleation kinetics performed, using Nyvlt’s approach, shows that the dextran accelerates the nucleation and that the nuclei are formed in the solution by instantaneous nucleation. The presence of dextran in the system causes a decrease in the growth rate of sucrose. The growth process of sucrose is governed by a Birth and Spread mechanism. The kinetic parameters of sucrose growth in aqueous solutions without and with dextran were estimated.


CrystEngComm ◽  
2021 ◽  
Author(s):  
Ting Wen ◽  
Hairong Wang ◽  
Chunrong Li ◽  
Jikun Xu ◽  
Chuntao Zhang

In order to investigate the nucleation behavior of arbidol hydrochloride monohydrate (AHM) in the aqueous THF (Tetrahydrofuran) solutions, metastable zone width (MSZW) was experimentally determined via the polythermal method, and...


2014 ◽  
Vol 53 (30) ◽  
pp. 12170-12178 ◽  
Author(s):  
Jiaoyu Peng ◽  
Yaping Dong ◽  
Liping Wang ◽  
LiLi Li ◽  
Wu Li ◽  
...  

2014 ◽  
Vol 60 (1) ◽  
pp. 185-191 ◽  
Author(s):  
Liping Wang ◽  
Haitao Feng ◽  
Jiaoyu Peng ◽  
Naijin Dong ◽  
Wu Li ◽  
...  

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