Dual Smoothing and Value Function Techniques for Variational Matrix Decomposition

2016 ◽  
pp. 3-1-3-34
Keyword(s):  
Value Function ◽  
Matrix Decomposition ◽  
Variational Matrix

Retesting the Shape-of-Voice Value Function

2005 ◽  
Author(s):  
Jaewon Ko ◽  
Layne Paddock ◽  
Kees Van den Bos ◽  
Gary J. Greguras ◽  
Kidok Nam ◽  
...  
Keyword(s):  
Value Function

The value function for time-related decisions

2011 ◽  
Author(s):  
Anouk Festjens ◽  
Siegfried Dewitte ◽  
Enrico Diecidue ◽  
Sabrina Bruyneel
Keyword(s):  
Value Function ◽  
The Value Function

A Survey of Network Embedding for Drug Analysis and Prediction

2020 ◽  
Vol 21 ◽  
Author(s):  
Zhixian Liu ◽  
Qingfeng Chen ◽  
Wei Lan ◽  
Jiahai Liang ◽  
Yiping Pheobe Chen ◽  
...  
Keyword(s):  
Deep Learning ◽  
Protein Function ◽  
Dimensional Space ◽  
Auxiliary Information ◽  
Matrix Decomposition ◽  
Drug Analysis ◽  
Machine Learning Algorithms ◽  
Superior Performance ◽  
Network Embedding ◽  
Similarity Estimation

: Traditional network-based computational methods have shown good results in drug analysis and prediction. However, these methods are time consuming and lack universality, and it is difficult to exploit the auxiliary information of nodes and edges. Network embedding provides a promising way for alleviating the above problems by transforming network into a low-dimensional space while preserving network structure and auxiliary information. This thus facilitates the application of machine learning algorithms for subsequent processing. Network embedding has been introduced into drug analysis and prediction in the last few years, and has shown superior performance over traditional methods. However, there is no systematic review of this issue. This article offers a comprehensive survey of the primary network embedding methods and their applications in drug analysis and prediction. The network embedding technologies applied in homogeneous network and heterogeneous network are investigated and compared, including matrix decomposition, random walk, and deep learning. Especially, the Graph neural network (GNN) methods in deep learning are highlighted. Further, the applications of network embedding in drug similarity estimation, drug-target interaction prediction, adverse drug reactions prediction, protein function and therapeutic peptides prediction are discussed. Several future potential research directions are also discussed.

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