Applied Molecular Biotechnology

2016 ◽  
Keyword(s):  
Molecular Biotechnology

The study of diagnostic techniques for the sources of Escherichia coli at Ta-An Beach

2009 ◽  
Vol 60 (2) ◽  
pp. 389-398
Author(s):  
Hoei-Yuan Hwang ◽  
Hung-Yuan Fang
Keyword(s):  
Escherichia Coli ◽  
Diagnostic Techniques ◽  
Contamination Source ◽  
E Coli ◽  
Standard Data ◽  
Land Drainage ◽  
Molecular Biotechnology ◽  
Central Taiwan ◽  
Micro Organisms ◽  
Beach Water Quality

Ta-an Beach in Taichung County, central Taiwan, was found to have exceeded 1,000 CFU/100 ml, 51% of the total monitoring records. It is difficult to identify the contamination source using traditional Escherichia coli and Enterococci analysis. Therefore, a more advanced method known as molecular biotechnology is adopted in this study to diagnose the sources of E. coli at Ta-An Beach. After comparing several different groups of micro-organisms in water samples, we know that there are E. coli and Bacillus. This shows that the beach water quality is indeed affected by contamination from land drainage, and the numbers of E. coli and non-E. coli coliform in land drainage is far greater than that normally found at the beach. The analytical methods and techniques used in this study were not significantly different from the results detected using standard data analysis. The proposed method has high stability and reliability, providing ways to track and identify future of contamination.

ON THE POSSIBLE USE OF EXOGENOUS HISTONES AND CATIONIC PEPTIDES IN MOLECULAR BIOTECHNOLOGY

2020 ◽  
Vol 19 (2) ◽  
Author(s):  
A.D. Nozdrachev ◽  
O.A. Goryukhina ◽  
S.V. Martyushin ◽  
I.V. Mishchenko
Keyword(s):  
Cationic Peptides ◽  
Molecular Biotechnology

scholarly journals The Osteoporosis/Microbiota Linkage: The Role of miRNA

2020 ◽  
Vol 21 (23) ◽  
pp. 8887 ◽  
Author(s):  
Massimo De Martinis ◽  
Lia Ginaldi ◽  
Alessandro Allegra ◽  
Maria Maddalena Sirufo ◽  
Giovanni Pioggia ◽  
...  
Keyword(s):  
Dynamic Equilibrium ◽  
Treatment Strategies ◽  
Therapeutic Agents ◽  
Osteoporosis Prevention ◽  
Regulate Gene Expression ◽  
Molecular Biotechnology ◽  
Non Coding Rnas ◽  
The Relationship ◽  
Complementary Mechanism

Hundreds of trillions of bacteria are present in the human body in a mutually beneficial symbiotic relationship with the host. A stable dynamic equilibrium exists in healthy individuals between the microbiota, host organism, and environment. Imbalances of the intestinal microbiota contribute to the determinism of various diseases. Recent research suggests that the microbiota is also involved in the regulation of the bone metabolism, and its alteration may induce osteoporosis. Due to modern molecular biotechnology, various mechanisms regulating the relationship between bone and microbiota are emerging. Understanding the role of microbiota imbalances in the development of osteoporosis is essential for the development of potential osteoporosis prevention and treatment strategies through microbiota targeting. A relevant complementary mechanism could be also constituted by the permanent relationships occurring between microbiota and microRNAs (miRNAs). miRNAs are a set of small non-coding RNAs able to regulate gene expression. In this review, we recapitulate the physiological and pathological meanings of the microbiota on osteoporosis onset by governing miRNA production. An improved comprehension of the relations between microbiota and miRNAs could furnish novel markers for the identification and monitoring of osteoporosis, and this appears to be an encouraging method for antagomir-guided tactics as therapeutic agents.

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