Applications of Porous Silicon Materials in Drug Delivery

2016 ◽  
pp. 353-378
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Silicon Materials

Nanostructured porous silicon materials: potential candidates for improving drug delivery

Nanomedicine ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. 1281-1284 ◽  
Author(s):  
Hélder A Santos ◽  
Jouni Hirvonen
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Silicon Materials

scholarly journals A Gentle Sedimentation Process for Size-Selecting Porous Silicon Microparticles to Be Used for Drug Delivery Via Fine Gauge Needle Administration

Silicon ◽  
2020 ◽  
Author(s):  
Elida Nekovic ◽  
Catherine J. Storey ◽  
Andre Kaplan ◽  
Wolfgang Theis ◽  
Leigh T. Canham
Keyword(s):  
Drug Delivery ◽  
Particle Size ◽  
Porous Silicon ◽  
Particle Sizes ◽  
Size Distributions ◽  
Particle Agglomeration ◽  
Gas Generation ◽  
Intravitreal Drug Delivery ◽  
Median Diameter ◽  
Experimental Values

AbstractBiodegradable porous silicon (pSi) particles are under development for drug delivery applications. The optimum particle size very much depends on medical use, and microparticles can outperform nanoparticles in specific instances. Here we demonstrate the ability of sedimentation to size-select ultrasmall (1–10 μm) nanoporous microparticles in common solvents. Size tunability is quantified for 1–24 h of sedimentation. Experimental values of settling times in ethanol and water are compared to those calculated using Stokes’ Law. Differences can arise due to particle agglomeration, internal gas generation and incomplete wetting. Air-dried and supercritically-dried pSi powders are shown to have, for example, their median diameter d (0.5) particle sizes reduced from 13 to 1 μm and from 20 to 3 μm, using sedimentation times of 6 and 2 h respectively. Such filtered microparticles also have much narrower size distributions and are hence suitable for administration in 27 gauge microneedles, commonly used in intravitreal drug delivery.

Porous Silicon as a Nanomaterial for Disperse Transport Systems of Targeted Drug Delivery to the Inner Ear

2018 ◽  
Vol 63 (9) ◽  
pp. 1352-1360 ◽  
Author(s):  
Yu. M. Spivak ◽  
A. O. Belorus ◽  
A. A. Panevin ◽  
S. G. Zhuravskii ◽  
V. A. Moshnikov ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Inner Ear ◽  
Targeted Drug Delivery ◽  
Transport Systems ◽  
Targeted Drug

scholarly journals Porous silicon in drug delivery devices and materials☆

2008 ◽  
Vol 60 (11) ◽  
pp. 1266-1277 ◽  
Author(s):  
E ANGLIN ◽  
L CHENG ◽  
W FREEMAN ◽  
M SAILOR
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Drug Delivery Devices

Nanostructured Metal Films Formed onto Porous Silicon Template

2016 ◽  
Vol 39 ◽  
pp. 235-255
Author(s):  
Hanna Bandarenka ◽  
Alexei Dolgiy ◽  
Eugene Chubenko ◽  
Sergei Redko ◽  
Kseniya Girel ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Transdermal Drug Delivery ◽  
Research Work ◽  
Metal Films ◽  
Morphological Pattern ◽  
Mechanical And Electrical Properties ◽  
Different Types ◽  
Review Reports ◽  
Nanostructured Metal

The review reports on the results of our research work on nanostructured metal films onto porous silicon. Principal steps of the techniques allowing fabrication of metal films completely inheriting morphological pattern of different types of porous silicon are presented. It is shown, that giving of the nanostructured pattern to metal films by means of porous silicon template opens their new structural, optical, mechanical and electrical properties, which can be successfully applied in nanoelectronics and biomedicine, particularly including devices based on superconductivity effect, SERS analysis with picomolar sensitivity and transdermal drug delivery by electroporation.

scholarly journals Optically monitored drug delivery patch based on porous silicon and polymer microneedles

2016 ◽  
Vol 7 (5) ◽  
pp. 1645 ◽  
Author(s):  
Principia Dardano ◽  
Alessandro Caliò ◽  
Jane Politi ◽  
Ilaria Rea ◽  
Ivo Rendina ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon

Microfluidic Assembly of Monodisperse Multistage pH-Responsive Polymer/Porous Silicon Composites for Precisely Controlled Multi-Drug Delivery

Small ◽  
2014 ◽  
Vol 10 (10) ◽  
pp. 2029-2038 ◽  
Author(s):  
Dongfei Liu ◽  
Hongbo Zhang ◽  
Bárbara Herranz-Blanco ◽  
Ermei Mäkilä ◽  
Vesa-Pekka Lehto ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Ph Responsive ◽  
Responsive Polymer ◽  
Microfluidic Assembly
Sign in / Sign up

Export Citation Format

Share Document