- Protein–Ligand Docking: From Basic Principles to Advanced Applications

2015 ◽  
pp. 172-205 ◽  
2013 ◽  
Vol 114 (2) ◽  
pp. 1371-1412 ◽  
Author(s):  
Michele Amato ◽  
Maurizia Palummo ◽  
Riccardo Rurali ◽  
Stefano Ossicini

2021 ◽  
Author(s):  
Ruoyang Liu ◽  
Ke Tian Tan ◽  
Yifan Gong ◽  
Yongzhi Chen ◽  
Zhuoer Li ◽  
...  

Covalent organic frameworks offer a molecular platform for integrating organic units into periodically ordered yet extended 2D and 3D polymers to create topologically well-defined polygonal lattices and built-in discrete micropores and/or mesopores.


2010 ◽  
Vol 20 (3) ◽  
pp. 100-105 ◽  
Author(s):  
Anne K. Bothe

This article presents some streamlined and intentionally oversimplified ideas about educating future communication disorders professionals to use some of the most basic principles of evidence-based practice. Working from a popular five-step approach, modifications are suggested that may make the ideas more accessible, and therefore more useful, for university faculty, other supervisors, and future professionals in speech-language pathology, audiology, and related fields.


2020 ◽  
Vol 91 (3) ◽  
pp. 31301
Author(s):  
Nabil Chakhchaoui ◽  
Rida Farhan ◽  
Meriem Boutaldat ◽  
Marwane Rouway ◽  
Adil Eddiai ◽  
...  

Novel textiles have received a lot of attention from researchers in the last decade due to some of their unique features. The introduction of intelligent materials into textile structures offers an opportunity to develop multifunctional textiles, such as sensing, reacting, conducting electricity and performing energy conversion operations. In this research work nanocomposite-based highly piezoelectric and electroactive β-phase new textile has been developed using the pad-dry-cure method. The deposition of poly (vinylidene fluoride) (PVDF) − carbon nanofillers (CNF) − tetraethyl orthosilicate (TEOS), Si(OCH2CH3)4 was acquired on a treated textile substrate using coating technique followed by evaporation to transform the passive (non-functional) textile into a dynamic textile with an enhanced piezoelectric β-phase. The aim of the study is the investigation of the impact the coating of textile via piezoelectric nanocomposites based PVDF-CNF (by optimizing piezoelectric crystalline phase). The chemical composition of CT/PVDF-CNC-TEOS textile was detected by qualitative elemental analysis (SEM/EDX). The added of 0.5% of CNF during the process provides material textiles with a piezoelectric β-phase of up to 50% has been measured by FTIR experiments. These results indicated that CNF has high efficiency in transforming the phase α introduced in the unloaded PVDF, to the β-phase in the case of nanocomposites. Consequently, this fabricated new textile exhibits glorious piezoelectric β-phase even with relatively low coating content of PVDF-CNF-TEOS. The study demonstrates that the pad-dry-cure method can potentially be used for the development of piezoelectric nanocomposite-coated wearable new textiles for sensors and energy harvesting applications. We believe that our study may inspire the research area for future advanced applications.


1996 ◽  
Vol 35 (05) ◽  
pp. 181-185 ◽  
Author(s):  
H. Herzog

SummaryThe measurement of blood flow in various organs and its visual presentation in parametric images is a major application in nuclear medicine. The purpose of this paper is to summarize the most important nuclear medicine procedures used to quantify regional blood flow. Starting with the first concepts introduced by Fick and later by Kety-Schmidt the basic principles of measuring global and regional cerebral blood are discussed and their relationships are explained. Different applications and modifications realized first in PET- and later in SPECT-studies of the brain and other organs are described. The permeability and the extraction of the different radiopharmaceuticals are considered. Finally some important instrumental implications are compared.


1976 ◽  
Vol 15 (02) ◽  
pp. 69-74
Author(s):  
M. Goldberg ◽  
B. Doyon

This paper describes a general data base management package, devoted to medical applications. SARI is a user-oriented system, able to take into account applications very different by their nature, structure, size, operating procedures and general objectives, without any specific programming. It can be used in conversational mode by users with no previous knowledge of computers, such as physicians or medical clerks.As medical data are often personal data, the privacy problem is emphasized and a satisfactory solution implemented in SARI.The basic principles of the data base and program organization are described ; specific efforts have been made in order to increase compactness and to make maintenance easy.Several medical applications are now operational with SARI. The next steps will mainly consist in the implementation of highly sophisticated functions.


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