scholarly journals Early Trauma and Increased Risk for Physical Aggression During Adulthood: The Moderating Role of MAOA Genotype

2015 ◽  
pp. 75-92
Author(s):  
Giovanni Frazzetto ◽  
Giorgio Di Lorenzo ◽  
Valeria Carola ◽  
Luca Proietti ◽  
Ewa Sokolowska ◽  
...  
PLoS ONE ◽  
2007 ◽  
Vol 2 (5) ◽  
pp. e486 ◽  
Author(s):  
Giovanni Frazzetto ◽  
Giorgio Di Lorenzo ◽  
Valeria Carola ◽  
Luca Proietti ◽  
Ewa Sokolowska ◽  
...  

2009 ◽  
Vol 19 (3) ◽  
pp. 535-555 ◽  
Author(s):  
Annie Renouf ◽  
Mara Brendgen ◽  
Sophie Parent ◽  
Frank Vitaro ◽  
Philip David Zelazo ◽  
...  

2020 ◽  
Author(s):  
Wen Wei ◽  
Yudong Lin ◽  
Tiantian Hong ◽  
siyang luo

Loneliness is a common problem in adulthood, with deleterious effects on mental health conditions. In the present study, we aimed to examine the predictors of loneliness, with a focus on genetic factors (COMT genotype) and maternal rearing style, and further consider how loneliness moderates the relationship between maternal rearing style and adult’s mental health. The present results showed that COMT genotype significantly moderated the relationship between maternal rejection and loneliness, while only individuals who perceived reject from their mothers and carried Val/Val genotype were at increased risk for developing loneliness. When considering the moderated mediation model, current findings demonstrated that COMT genotype moderated the indirect effects of maternal reject and social anxiety as well as life satisfaction, and these effects are significant cross-age. Specifically, with Val/Val genotype, individuals who received a high rejection from the mother would influence their mental health through loneliness. These findings contribute to a further understanding of the environmental and genetic basis of loneliness and its influence on adulthood.


2020 ◽  
pp. 1-8
Author(s):  
Yufei Li ◽  
Samantha R Rosenthal

Abstract Objective: To examine the association between food insecurity (FI) and obesity, measured by BMI and waist circumference (WC), among young adults and test the moderating role of biological sex and the mediating role of diet healthfulness (DH). Design: Cross-sectional. Setting: National Health and Nutrition Examination Survey 2011–2016. Participants: The sample included 4667 young adults aged 18–35 years. Results: Given the interaction terms between sex and FI, biological sex was a moderator between both FI and WC (P = 0·031) and FI and BMI (P = 0·007) among young adults. FI was associated with a 1·16 kg/m2 higher BMI (95 % CI 0·27, 2·05) and a 2·09 cm larger WC (95 % CI 0·05, 4·14) among young female adults, while FI was associated with a 0·26 kg/m2 higher BMI (95 % CI –0·65, 1·16) and a 0·78 cm larger WC (95 % CI −1·13, 2·89) among young male adults. DH mediated the relationships between both FI and BMI (indirect effect β = 0·14; 95 % CI 0·05, 0·23) and FI and WC (indirect effect β = 0·31; 95 % CI 0·10, 0·51) among females. Females with FI had poorer DH and thus had higher BMI and larger WC. Conclusions: Young female adults with FI were more likely to experience overall and abdominal obesity compared with their male counterparts. Results also suggest that females with FI had poorer DH and thus had increased risk of both abdominal and overall obesity.


Crisis ◽  
2020 ◽  
Vol 41 (2) ◽  
pp. 82-88 ◽  
Author(s):  
Bob Lew ◽  
Ksenia Chistopolskaya ◽  
Yanzheng Liu ◽  
Mansor Abu Talib ◽  
Olga Mitina ◽  
...  

Abstract. Background: According to the strain theory of suicide, strains, resulting from conflicting and competing pressures in an individual's life, are hypothesized to precede suicide. But social support is an important factor that can mitigate strains and lessen their input in suicidal behavior. Aims: This study was designed to assess the moderating role of social support in the relation between strain and suicidality. Methods: A sample of 1,051 employees were recruited in Beijing, the capital of China, through an online survey. Moderation analysis was performed using SPSS PROCESS Macro. Social support was measured with the Multidimensional Scale of Perceived Social Support, and strains were assessed with the Psychological Strains Scale. Results: Psychological strains are a good predictor of suicidality, and social support, a basic need for each human being, moderates and decreases the effects of psychological strains on suicidality. Limitations: The cross-sectional survey limited the extent to which conclusions about causal relationships can be drawn. Furthermore, the results may not be generalized to the whole of China because of its diversity. Conclusion: Social support has a tendency to mitigate the effects of psychological strains on suicidality.


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