- PARAMETERS OF MOBILITY FOR POLLUTION BY SODIUM ARSENITE FOR SOIL OF KAMBARKA DISTRICT

2015 ◽  
pp. 234-241
Keyword(s):  
Sodium Arsenite

Modulatory Role of Kolaviron (KV), a Biflavonoid from Garcinia kola, in Sodium Arsenite-Induced Hepatotoxicity and Haematotoxicity in Rats

2016 ◽  
Vol 23 (1) ◽  
pp. 54
Author(s):  
Olalekan Samson Agboola ◽  
Ademola Adetokunbo Oyagbemi ◽  
Temidayo Olutayo Omobowale ◽  
Ebunoluwa Rachel Asenuga ◽  
Adebowale Bernard Saba
Keyword(s):  
Sodium Arsenite ◽  
Garcinia Kola

scholarly journals Comparative effects of ethanol leaf and stem bark extracts of Irvingia gabonensis (BUSH MANGO) on sodium arsenite-induced lipid profile perturbtions in wistar rats

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Efosa Godwin Ewere ◽  
Ngozi Paulinus Okolie ◽  
Erhunmwunsee Dalton Avan ◽  
Patience Edet Umoh
Keyword(s):  
Lipid Profile ◽  
Wistar Rats ◽  
Sodium Arsenite ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Stem Bark ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Irvingia Gabonensis

Abstract Background Exposure to arsenic orchestrates a myriad of noxious health effects, including cancer. Different parts of Irvingia gabonensis are used as herbal remedies in traditional medicine. In this study, the comparative effects of the ethanol leaf (ELEIG) and stem bark extracts (ESEIG) of Irvingia gabonensis on sodium arsenite (SA)-induced lipid profile disturbances in Wistar rats were investigated. Methods Fifty five Wistar rats weighing between 100 g and 179 g were distributed into eleven groups (n=5). Group 1 (control) received feed and water ad libitum. Group 2 received SA at a dose of 4.1 mg/kg body weight (kgbw) for 14 days. Groups 3–11 were treated with the extracts with or without SA. Treatment was done by oral intubation for 14 days. Serum concentrations of total cholesterol (TC), triacylglycerol (TAG), high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c), total lipids (TL) and atherogenic index of plasma (AIP) were used to determine the lipid profile effects of the extracts. Results Exposure to SA caused significant (p ˂ 0.05) increases in all assayed parameters, relative to control. Post-treatment and simultaneous treatment with ELEIG and ESEIG mitigated the effects of SA. In addition, ELEIG alone at various doses produced results comparable with control values. However, ESEIG alone caused significant (p ˂ 0.05) increases in all assayed parameters, relative to control. Conclusion These results show that ELEIG and ESEIG ameliorate SA-induced lipid profile disturbances in Wistar rats. However, long-term administration of ESEIG alone may be discouraged.

Methylation of Arsenic by Freshwater Green Algae

1983 ◽  
Vol 40 (8) ◽  
pp. 1254-1257 ◽  
Author(s):  
M. D. Baker ◽  
P. T. S. Wong ◽  
Y. K. Chau ◽  
C. I. Mayfield ◽  
W. E. Inniss
Keyword(s):  
Green Algae ◽  
Lake Water ◽  
Sodium Arsenite ◽  
Basal Medium ◽  
Arsenic Species ◽  
Freshwater Ecosystems ◽  
Dimethylarsinic Acid ◽  
Additional Source ◽  
Arsenic Compounds ◽  
Methylarsonic Acid

Isolates from four genera of freshwater green algae were capable of methylating sodium arsenite in lake water and Bold's basal medium. Analysis of the liquid phase of the methylation flasks revealed the presence of methylarsonic acid, dimethylarsinic acid, and trimethylarsine oxide. Volatile arsine and methylarsines were not detected in the headspace gases presumably because of the inability of the algae to reduce completely the methylated–arsenic species. Although the algae varied with respect to their methylating abilities, the levels of methylated–arsenic compounds were always significantly higher when the algae were grown in lake water. This may have been due to the lower phosphate concentration in the lake water. We suggest that arsenic methylation by green algae constitutes an additional source for the formation and cycling of organo-arsenic compounds in freshwater ecosystems.

Influence of Soil Type on Soil Sterilization with Sodium Arsenite

Weeds ◽  
1956 ◽  
Vol 4 (1) ◽  
pp. 11 ◽  
Author(s):  
R. E. Frans ◽  
C. R. Skogley ◽  
G. H. Ahlgren
Keyword(s):  
Soil Type ◽  
Sodium Arsenite ◽  
Soil Sterilization

Male reproductive toxicity of sodium arsenite in mice

2004 ◽  
Vol 23 (8) ◽  
pp. 399-403 ◽  
Author(s):  
Niraj Pant ◽  
R C Murthy ◽  
S P Srivastava
Keyword(s):  
Drinking Water ◽  
Sodium Arsenite ◽  
Sperm Count ◽  
Prostate Gland ◽  
Reproductive Toxicity ◽  
Atomic Absorption Spectrophotometry ◽  
Reproductive Organs ◽  
Oral Exposure ◽  
Human Beings ◽  
Testicular Weight

The effect of chronic oral exposure to arsenic on male mouse testicular and accessory sex organ weights, sperm parameters and testicular marker enzymes was studied. In addition, the distribution of arsenic in reproductive organs was measured using atomic absorption spectrophotometry. Sodium arsenite administered to mice (Mus musculus) via drinking water at a dose of 53.39 βmol/L (4 ppm As) for 365 days caused a decrease in the absolute and relative testicular weight. However, epididymal and accessory sex organ weight was similar to control. The activities of marker testicular enzymes such as sorbitol dehydrogenase, acid phosphatase and 17β-hydroxysteroid dehydrogenase (17β-HSD) were significantly decreased, but those of lactate dehydrogenase and γ-glutamyl transpeptidase (γ-GT) were significantly increased. A decrease in sperm count and sperm motility, along with an increase in abnormal sperm, was observed in arsenite-exposed mice. A significant accumulation of arsenic in testes, epididymis, seminal vesicle and prostate gland was observed in treated animals. Thus long term exposure (365 days) at the dose level of 53.39 μmol/L sodium arsenite (4 ppm As), to which human beings are likely to be exposed via drinking water, may cause testicular and spermatotoxic effect.

Use of RAPD to detect sodium arsenite-induced DNA damage in human lymphoblastoid cells

Toxicology ◽  
2007 ◽  
Vol 239 (1-2) ◽  
pp. 108-115 ◽  
Author(s):  
Yuan-Cho Lee ◽  
Vivian.C. Yang ◽  
Tsu-Shing Wang
Keyword(s):  
Dna Damage ◽  
Sodium Arsenite ◽  
Lymphoblastoid Cells

scholarly journals Mammalian microtubule P-body dynamics are mediated by nesprin-1

2014 ◽  
Vol 205 (4) ◽  
pp. 457-475 ◽  
Author(s):  
Dipen Rajgor ◽  
Jason A. Mellad ◽  
Daniel Soong ◽  
Jerome B. Rattner ◽  
Marvin J. Fritzler ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Nuclear Envelope ◽  
Sodium Arsenite ◽  
Sr Proteins ◽  
Dominant Negative ◽  
Dependent Manner ◽  
Processing Bodies ◽  
Spectrin Repeat ◽  
Microtubule Attachment ◽  
Body Dynamics

Nesprins are a multi-isomeric family of spectrin-repeat (SR) proteins, predominantly known as nuclear envelope scaffolds. However, isoforms that function beyond the nuclear envelope remain poorly examined. Here, we characterize p50Nesp1, a 50-kD isoform that localizes to processing bodies (PBs), where it acts as a microtubule-associated protein capable of linking mRNP complexes to microtubules. Overexpression of dominant-negative p50Nesp1 caused Rck/p54, but not GW182, displacement from microtubules, resulting in reduced PB movement and cross talk with stress granules (SGs). These cells disassembled canonical SGs induced by sodium arsenite, but not those induced by hydrogen peroxide, leading to cell death and revealing PB–microtubule attachment is required for hydrogen peroxide-induced SG anti-apoptotic functions. Furthermore, p50Nesp1 was required for miRNA-mediated silencing and interacted with core miRISC silencers Ago2 and Rck/p54 in an RNA-dependent manner and with GW182 in a microtubule-dependent manner. These data identify p50Nesp1 as a multi-functional PB component and microtubule scaffold necessary for RNA granule dynamics and provides evidence for PB and SG micro-heterogeneity.

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