scholarly journals - Development of a Broad-Host Synthetic Biology Toolbox for Ralstonia eutropha and Its Application to Engineering Hydrocarbon Biofuel Production

2015 ◽  
pp. 230-249
Keyword(s):  
Synthetic Biology ◽  
Ralstonia Eutropha ◽  
Biofuel Production

scholarly journals Development of a broad-host synthetic biology toolbox for ralstonia eutropha and its application to engineering hydrocarbon biofuel production

2013 ◽  
Vol 12 (1) ◽  
pp. 107 ◽  
Author(s):  
Changhao Bi ◽  
Peter Su ◽  
Jana Müller ◽  
Yi-Chun Yeh ◽  
Swapnil R Chhabra ◽  
...  
Keyword(s):  
Synthetic Biology ◽  
Ralstonia Eutropha ◽  
Biofuel Production

Synthetic Biology of Microbial Biofuel Production

2013 ◽  
pp. 207-223
Author(s):  
Gregory Bokinsky ◽  
Dan Groff ◽  
Jay Keasling
Keyword(s):  
Synthetic Biology ◽  
Biofuel Production ◽  
Microbial Biofuel

scholarly journals Yeast synthetic biology toolbox and applications for biofuel production

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Ching-Sung Tsai ◽  
Suryang Kwak ◽  
Timothy L. Turner ◽  
Yong-Su Jin
Keyword(s):  
Synthetic Biology ◽  
Biofuel Production

scholarly journals The Role of Synthetic Biology in the Design of Microbial Cell Factories for Biofuel Production

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Verónica Leticia Colin ◽  
Analía Rodríguez ◽  
Héctor Antonio Cristóbal
Keyword(s):  
Synthetic Biology ◽  
Industrial Applications ◽  
Microbial Cell ◽  
Biodiesel Production ◽  
Biofuel Production ◽  
Attractive Alternative ◽  
Efficient Production ◽  
Microbial Cell Factories ◽  
Cell Factories

Insecurity in the supply of fossil fuels, volatile fuel prices, and major concerns regarding climate change have sparked renewed interest in the production of fuels from renewable resources. Because of this, the use of biodiesel has grown dramatically during the last few years and is expected to increase even further in the future. Biodiesel production through the use of microbial systems has marked a turning point in the field of biofuels since it is emerging as an attractive alternative to conventional technology. Recent progress in synthetic biology has accelerated the ability to analyze, construct, and/or redesign microbial metabolic pathways with unprecedented precision, in order to permit biofuel production that is amenable to industrial applications. The review presented here focuses specifically on the role of synthetic biology in the design of microbial cell factories for efficient production of biodiesel.

scholarly journals Trends in Synthetic Biology in the Bioeconomy of Non-food-Competing Biofuels

2021 ◽  
Author(s):  
Antônio Luiz Fantinel ◽  
Rogério Margis ◽  
Edson Talamini ◽  
Homero Dewes
Keyword(s):  
Los Angeles ◽  
Synthetic Biology ◽  
Raw Materials ◽  
Renewable Energy Sources ◽  
Redox Balance ◽  
The United States ◽  
Biofuel Production ◽  
Bioenergy Production ◽  
Synthetic Promoters ◽  
Interdisciplinary Field

Despite the acknowledged relevance of renewable energy sources, biofuel production supported by food-related agriculture has faced severe criticism. One way to minimize the considered negative impacts is the use of sources of non-food biomass or wastes. Synthetic biology (SB) embraces a promising complex of technologies for biofuel production from non-edible and sustainable raw materials. Therefore, it is pertinent to identify the global evolution of investments, concepts, and techniques underlying the field in support of policy formulations for sustainable bioenergy production. We mapped the SB scientific knowledge related to biofuels using software that combines information visualization methods, bibliometrics, and data mining algorithms. The United States and China have been the leading countries in developing SB technologies. Technical University of Denmark and Tsinghua University are the institutions with higher centrality and have played prominent roles besides UC-Los Angeles and Delft University Technology. We identified six knowledge clusters under the terms: versatile sugar dehydrogenase, redox balance principle, sesquiterpene production, Saccharomyces cerevisiae, recombinant xylose-fermenting strain, and Clostridium saccharoperbutylacetonicum N1-4. The emerging trends refer to specific microorganisms, processes, and products. Yarrowia lipolytica, Oleaginous yeast, E. coli, Klebsiella pneumoniae, Phaeodactylum tricornutum, and Microalgae are the most prominent microorganisms, mainly from the year 2016 onwards. Anaerobic digestion, synthetic promoters, and genetic analysis appear as the most relevant platforms of new processes. Improved biofuels, bioethanol, and N-butanol are at the frontier of the development of SB-derived products. Synthetic biology is a dynamic interdisciplinary field in environmentally friendly bioenergy production pushed by growing social concerns and the emergent bioeconomy.

scholarly journals Systems-Level Synthetic Biology for Advanced Biofuel Production

2015 ◽  
Author(s):  
Anne Ruffing ◽  
Travis J. Jensen ◽  
Lucas Marshall Strickland ◽  
Stephen Meserole ◽  
David Tallant
Keyword(s):  
Synthetic Biology ◽  
Biofuel Production ◽  
Advanced Biofuel

scholarly journals Synthetic biology toolkit for engineering Cupriviadus necator H16 as a platform for CO2 valorization

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Haojie Pan ◽  
Jia Wang ◽  
Haoliang Wu ◽  
Zhongjian Li ◽  
Jiazhang Lian
Keyword(s):  
Synthetic Biology ◽  
Genetic Engineering ◽  
Genome Engineering ◽  
Ralstonia Eutropha ◽  
Heterologous Gene Expression ◽  
Value Added ◽  
Cell Factory ◽  
Main Body ◽  
Cell Factories ◽  
Value Added Products

Abstract Background CO2 valorization is one of the effective methods to solve current environmental and energy problems, in which microbial electrosynthesis (MES) system has proved feasible and efficient. Cupriviadus necator (Ralstonia eutropha) H16, a model chemolithoautotroph, is a microbe of choice for CO2 conversion, especially with the ability to be employed in MES due to the presence of genes encoding [NiFe]-hydrogenases and all the Calvin–Benson–Basham cycle enzymes. The CO2 valorization strategy will make sense because the required hydrogen can be produced from renewable electricity independently of fossil fuels. Main body In this review, synthetic biology toolkit for C. necator H16, including genetic engineering vectors, heterologous gene expression elements, platform strain and genome engineering, and transformation strategies, is firstly summarized. Then, the review discusses how to apply these tools to make C. necator H16 an efficient cell factory for converting CO2 to value-added products, with the examples of alcohols, fatty acids, and terpenoids. The review is concluded with the limitation of current genetic tools and perspectives on the development of more efficient and convenient methods as well as the extensive applications of C. necator H16. Conclusions Great progress has been made on genetic engineering toolkit and synthetic biology applications of C. necator H16. Nevertheless, more efforts are expected in the near future to engineer C. necator H16 as efficient cell factories for the conversion of CO2 to value-added products.

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