Compliance with Antiepileptic Drug Treatment and the Risk of SUDEP

2015 ◽  
pp. 297-300
Author(s):  
Torbjörn Tomson
Keyword(s):  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Antiepileptic Drug Treatment

Effects of Antiepileptic Drug Treatment on the Background Frequency of EEGs in Epileptic Patients

1993 ◽  
Vol 10 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Geoffrey K. Herkes ◽  
Terrence D. Lagerlund ◽  
Frank W. Sharbrough ◽  
Mervyn J. Eadie
Keyword(s):  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Background Frequency ◽  
Epileptic Patients ◽  
Antiepileptic Drug Treatment

Cortical excitability during prolonged antiepileptic drug treatment and drug withdrawal

2005 ◽  
Vol 116 (5) ◽  
pp. 1105-1112 ◽  
Author(s):  
H.W. Lee ◽  
H.J. Seo ◽  
L.G. Cohen ◽  
A. Bagic ◽  
W.H. Theodore
Keyword(s):  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Drug Withdrawal ◽  
Cortical Excitability ◽  
Antiepileptic Drug Treatment

scholarly journals Zonisamide Induces Crystalluria without Urinary pH Changes in Children and Young Adults

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Tohshin Go
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Childhood Onset ◽  
Urinary Ph ◽  
Alkaline Urine ◽  
Antiepileptic Drug Treatment ◽  
Children And Young Adults ◽  
Disabled Patients

Purpose. Adjunctive zonisamide therapy was demonstrated to be beneficial for multiple-disabled patients with refractory childhood-onset epilepsy. Zonisamide is well tolerated, but urolithiasis and calcium sludge in the bladder were sometimes described in patients treated with antiepileptic drug polytherapy including zonisamide. In previous studies, alkaline urine and crystalluria were shown to be risk factors for urolithiasis. Therefore, the effects of zonisamide addition and withdrawal on the urinary pH and crystalluria were investigated in patients treated with antiepileptic drug polytherapy to clarify the cause of urolithiasis induced by zonisamide. Methods. The urinary pH and the degree of crystalluria were retrospectively studied in epilepsy patients one month after the addition or withdrawal of zonisamide as part of their antiepileptic drug treatment regimen over the previous three years. Results. A total of 27 zonisamide-on patients and 16 zonisamide-off patients were enrolled in the study. The urinary pH did not change after the addition or withdrawal of zonisamide. However, the degree of crystalluria significantly increased after the addition () of zonisamide and decreased after its withdrawal (). Conclusions. Zonisamide induces crystalluria without alkalinization of the urine. Crystalluria should be carefully monitored in patients treated with zonisamide to prevent urolithiasis.

Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2)

2009 ◽  
Vol 120 (6) ◽  
pp. 402-410 ◽  
Author(s):  
B. Legros ◽  
P. Boon ◽  
P. De Jonghe ◽  
B. Sadzot ◽  
K. Van Rijckevorsel ◽  
...  
Keyword(s):  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Epilepsy Treatment ◽  
Antiepileptic Drug Treatment ◽  
Belgian Study

scholarly journals Antiepileptic drug treatment of generalized tonic–clonic seizures: An evaluation of regulatory data and five criteria for drug selection

2018 ◽  
Vol 82 ◽  
pp. 91-103 ◽  
Author(s):  
Simon D. Shorvon ◽  
Pedro E. Bermejo ◽  
Ayana A. Gibbs ◽  
Gilles Huberfeld ◽  
Reetta Kälviäinen
Keyword(s):  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Drug Selection ◽  
Regulatory Data ◽  
Antiepileptic Drug Treatment ◽  
Clonic Seizures
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