Omega-3 Fatty Acids and Sudden Unexpected Death in Epilepsy: A Translational Approach

2015 ◽  
pp. 269-274
Author(s):  
Fulvio Scorza ◽  
Esper Cavalheiro ◽  
Antonio-Carlos de Almeida ◽  
Carla Scorza ◽  
Mariana Nejm ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death ◽  
Translational Approach

scholarly journals Fish consumption, contaminants and sudden unexpected death in epilepsy: many more benefits than risks

2010 ◽  
Vol 70 (3) ◽  
pp. 665-670 ◽  
Author(s):  
FA. Scorza ◽  
RM. Cysneiros ◽  
RM. Arida ◽  
VC. Terra ◽  
HR. Machado ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fish Consumption ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death ◽  
Positive Effects ◽  
Increased Risk ◽  
Fish And Shellfish

People with epilepsy have an increased risk of dying prematurely and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP). SUDEP is mainly a problem for patients with chronic uncontrolled epilepsy. The ultimate goal of research in SUDEP is to develop new methods to prevent it and actions other than medical and surgical therapies that could be very useful. Nutritional aspects, i.e., omega-3 fatty acids deficiency, could have an interesting role in this scenario. Some animal and clinical studies have suggested that omega-3 fatty acids could be useful in the prevention and treatment of epilepsy and hence SUDEP. It has been ascertained that the only foods that provide large amounts of omega-3 are seafood (fish and shellfish); however, some fish are contaminated with methylmercury, which may counteract the positive effects of omega-3 fatty acids. Our update review summarises the knowledge of the role of fish consumption on epilepsy research.

Omega-3 Fatty Acids in Sudden Unexpected Death in Epilepsy

2010 ◽  
Author(s):  
Fulvio Scorza ◽  
Esper Cavalheiro ◽  
Ricardo Arida ◽  
Vera Terra ◽  
Carla Scorza ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death

The other side of the coin: Beneficiary effect of omega-3 fatty acids in sudden unexpected death in epilepsy

2008 ◽  
Vol 13 (2) ◽  
pp. 279-283 ◽  
Author(s):  
Fulvio A. Scorza ◽  
Roberta M. Cysneiros ◽  
Ricardo M. Arida ◽  
Vera C. Terra-Bustamante ◽  
Marly de Albuquerque ◽  
...  
Keyword(s):  
Fatty Acids ◽  
The Other ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death

Assessing the link between omega-3 fatty acids, cardiac arrest, and sudden unexpected death in epilepsy

2009 ◽  
Vol 14 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Ameer Y. Taha ◽  
Flaviu A. Ciobanu ◽  
Anjali Saxena ◽  
W. McIntyre Burnham
Keyword(s):  
Fatty Acids ◽  
Cardiac Arrest ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death

scholarly journals Epilepsy and sudden unexpected death in epilepsy?: Eat more fish! A group hypothesis

2009 ◽  
Vol 67 (3b) ◽  
pp. 927-929 ◽  
Author(s):  
Roberta M. Cysneiros ◽  
Vera C. Terra ◽  
Hélio R. Machado ◽  
Ricardo M. Arida ◽  
Marly de Albuquerque ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Neurological Diseases ◽  
Sudden Unexpected Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death ◽  
Omega 3 Fatty Acid ◽  
Risk Of Death ◽  
Fatty Acid Deficiency ◽  
The Brain

Epilepsy is the commonest serious neurological disorder and individuals with epilepsy are at higher risk of death than the general population and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures play a potential role. The ultimate goal of SUDEP research is to develop methods to prevent it and nutritional aspects such as omega-3 fatty acid deficiency may have an interesting role in this scenario. Omega-3 fatty acids reduce the risk of cardiovascular mortality and are important for treating or preventing some neurological diseases, including epilepsy. A dietary modification or nutritional supplements increasing the ingestion of omega-3 fatty acids may help to ''save the brain".

scholarly journals Omega-3 intake in people with epilepsy under regular hemodialysis program: here to stay

2013 ◽  
Vol 71 (7) ◽  
pp. 474-477
Author(s):  
Carla Alessandra Scorza ◽  
Ricardo Mario Arida ◽  
Roberta Monterazzo Cysneiros ◽  
Esper Abrão Cavalheiro ◽  
Fulvio Alexandre Scorza
Keyword(s):  
Risk Factors ◽  
Fatty Acids ◽  
Sudden Cardiac Death ◽  
Renal Insufficiency ◽  
Cardiac Death ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Unexpected Death ◽  
The Many ◽  
Regular Hemodialysis

Among the many risk factors suggested for sudden unexpected death in epilepsy (SUDEP), higher frequency of seizures is a very consistent issue. Furthermore, it has been established that hemodialysis-associated seizure is a complication of the dialysis procedure. Thus, since a possible relation between cardiovascular abnormalities and SUDEP among patients with chronic renal insufficiency in regular hemodialysis program should not be neglected, we propose in this paper that omega-3 fatty acids offer opportunities for prevention of sudden cardiac death or improved treatment in people with epilepsy under the regular hemodialysis program.

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