Cutaneous Cell- and Gene-Based Therapies for Inherited and Acquired Skin Disorders

Introduction: At present there are no exact epidemiologic data on the prevalence of neonatal skin disorders and birth marks in Hungary. Aim: The aim of the authors was to investigate the prevalence of skin disorders in mature healthy neonates after birth. Method: The survey was carried out in the Neonatal Care Unit at the Department of Obstetrics and Gynaecology at the University of Szeged between April, 2012 and May, 2013. Results:A total of 2289 newborn infants underwent whole-body screening skin examinations. At least one skin manifestation was found in 63% of the neonates. The major groups of skin disorders were transient benign cutaneous lesions, vascular lesions, pigmented lesions, traumatic, iatrogenic, congenital or acquired disorders with skin injuries, developmental abnormalities and benign skin tumours. The most frequent transient cutaneous lesions were erythema toxicum neonatorum, sebaceous hyperplasia and desquamation. The most common vascular lesions were naevus simplex, haemangioma and haemangioma precursor lesion, while the most frequently observed pigmented lesions were congenital melanocytic naevi and Mongolian spot. Conclusions: In the vast majority of cases, special treatment was not necessary, but 5.27% of the neonates required local dermatologic therapy, and in 9.2% of neonates follow up was recommended. Orv. Hetil., 2014, 155(13), 500–508.

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Comparative Pharmacognostical Evaluation of Khadirashtaka yavakuta (Powder) and Kashaya (Decoction)

International Journal of Pharmacognosy and Phytochemical Research ◽

10.25258/phyto.v9i10.10456 ◽

2017 ◽

Vol 9 (10) ◽

Author(s):

Chandani Goswami ◽

V. D. Hitesh Vyas ◽

Harisha C. R.

Keyword(s):

Dietary Habits ◽

Prolonged Exposure ◽

Skin Diseases ◽

Metabolic Changes ◽

Skin Disorders ◽

Coarse Powder ◽

Crude Drugs ◽

Standard Range

Khadirashtaka Kashaya, a compound Ayurvedic formulation is prescribed mainly in the management of Kushtha Vyadhi( skin diseases), Visarp Roga (erysipelous) and Masoorika (type of measels) and it is mentioned in Sangraha Grantha like, Yogaratnakara, Gadanighraha, Bhaishajya Ratnavali. The era is rising with many of novel dietary habits and lifestyle which are ill-assorted with health. Consumption of incompatible food combinations, heavy meals; faulty temperature acclimatisation leads to several metabolic changes which results in unhealthy skin. Their prolonged exposure leads to long lasting dermatological abnormalities having vitiated Rasa and Rakta Dhatu. Khadirashtaka Kashaya helps to break the pathogenesis of skin disorders by its bitter-astringent taste, light and dry properties as well as blood purifying activity. Till date no work was found having comparatively scientifically analysed on this drug. In Present study Khadirashtaka Kashaya and Khadirashtaka choorna have been evaluated for Pharmacognostical analysis. Finished product microscopy and decoction showing the quality and genuineness of all the constituents of Khadirashtaka Kashaya (Decoction) has been done. Organoleptic features of coarse powder made out of the crude drugs were within the standard range

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An exploratory study to evaluate the efficacy and safety of bilastine in reducing pruritus in patients with chronic spontaneous urticaria and other skin disorders.

10.26226/morressier.5acdc65dd462b8029238dcfc ◽

2018 ◽

Author(s):

E. Serra

Keyword(s):

Exploratory Study ◽

Chronic Spontaneous Urticaria ◽

Efficacy And Safety ◽

Skin Disorders

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Faculty Opinions recommendation of Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11927956.13043056 ◽

2011 ◽

Author(s):

Gabriella Fabbrocini

Keyword(s):

Skin Disorders ◽

Chemical Peels

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To evaluate the efficacy of Jalaukavacharana followed by Khadira Prayoga in Vicharchika w.s.r to Eczema

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v2i4.9323 ◽

2017 ◽

Vol 2 (4) ◽

Author(s):

Kulkarni Sharad ◽

Syeda Ather Fathima ◽

Naveen B. S.

Keyword(s):

Incidence Rate ◽

Clinical Features ◽

Skin Disease ◽

Skin Disorder ◽

Age Groups ◽

High Rate ◽

Main Line ◽

Treatment Modalities ◽

Skin Disorders

Vicharchika (Eczema) is a skin disorder with predominance of Pitta Kapha Dosha, with clinical features like Kandu, Srava, Pidaka, Shyavata, Rookshata, Raji, Ruja and Daha mainly in the extremities. It is the second commonest skin disease affecting all age groups, with incidence rate of 2-3% and high rate of recurrence. Ayurveda emphasizes Shodhana therapy as the main line of treatment in skin disorders. Raktamokshana is indicated as Rakta is mainly involved in Vicharchika. In the present study, two treatment modalities were selected to find out which is more appropriate.

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