Oxidative Stress Dened as a Deadly Free Radical- Mediated Chain Reaction: Case History of Paraquat

2014 ◽  
pp. 30-37
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Case History ◽  
Chain Reaction ◽  
History Of

scholarly journals Oxidative stress in animals: role in oncogenesis from pathomorphologist view

2020 ◽  
Vol 2020 (5) ◽  
pp. 27-30
Author(s):  
Natal'ya Mitrohina
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Free Radical ◽  
Inflammatory Reaction ◽  
Oxygen Free Radicals ◽  
Cell Damage ◽  
Chain Reaction ◽  
Stress Development ◽  
Action Mechanisms ◽  
Cell Hypoxia

Oxidative stress is a pathological accumulation of free radicals that contribute to the launch of intracellular damaging action mechanisms. Free radical is an atom possessing free or missing electron, and seeking to restore the lost electron, taking it from other molecules ― as a result a new free radical is formed. The mechanism is chain reaction-based. Hypoxia acts as an additional stimulus to the appearance of oxygen free radicals. Cell hypoxia develops following any type of cell damage: mechanical, bacteriological, chemical, etc. Cell hypoxia inevitably leads to the development of an inflammatory reaction, which is followed by the formation of oxygen free radicals and, as a result, by oxidative stress development.

scholarly journals History of Chemical Routes towards Cyclic Non-Enzymatic Oxygenated Metabolites of Polyunsaturated Fatty Acids

Synthesis ◽  
2018 ◽  
Vol 50 (17) ◽  
pp. 3257-3280 ◽  
Author(s):  
Camille Oger ◽  
Claire Cuyamendous ◽  
Aurélien de la Torre ◽  
Mathieu Candy ◽  
Alexandre Guy ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Free Radical ◽  
Polyunsaturated Fatty Acids ◽  
Total Synthesis ◽  
Scientific Community ◽  
Biological Properties ◽  
Biological Processes ◽  
Total Syntheses ◽  
History Of

Enzymatically formed oxygenated metabolites of polyunsaturated fatty acids (PUFA) are of great interest for the scientific community being mediators and biomarkers in the physiological and pathological regulation of many key biological processes. More recently; metabolites of PUFA formed through a non-enzymatic free radical pathway have gained interest in diseases linked with oxidative stress. Thus, synthetic strategies leading to the total synthesis of such metabolites are an essential field of research, and this review will cover a structural presentation, will discuss their biological interests, and present total syntheses reported between 2008 and 2017.1 Introduction2 Non-Enzymatic Metabolites of PUFAs2.1 Where Do They Come From?2.2 Why Are They Interesting Metabolites?2.3 A Huge Family of Natural Compounds2.3.1 Presentation of All Families2.3.1.1 Isoprostanoids2.3.1.2 Isofuranoids2.3.1.3 Isoketals2.3.2 Nomenclature of These Metabolites2.3.2.1 Isoprostanoids2.3.2.2 Isofuranoids2.3.2.3 Isoketals3 Total Synthesis Strategies3.1 Isoprostanoids3.2 Isofuranoids3.3 Isoketals4 The Discoveries Behind the Synthesis4.1 Recent Identification and Biomarkers Roles of Isoprostanes and Isofuranes4.2 Biological Properties4.2.1 Phytoprostanes, Isoprostanes, and Neuroprostanes4.2.2 Epoxy-isoprostanes5 Conclusion

Unlocking Reserves, Fracturing Tight Gas-Condensate Bearing Sandstone: The Case History of a North African Field (Algeria)

2013 ◽  
Author(s):  
Lucio Bertoldi ◽  
Raffaele Perfetto ◽  
Francesca Rinaldi ◽  
Gabriele Carpineta ◽  
Luis Granado ◽  
...  
Keyword(s):  
Case History ◽  
Gas Condensate ◽  
Tight Gas ◽  
North African ◽  
History Of

Deep Workover Challenges of an HP/HT Sour Gas Well - Case History of Mutriba 12

2011 ◽  
Author(s):  
Mohammed Jasem Al-Saeedi ◽  
Fayez Abdulrahman Al Fayez ◽  
Dakhil Rasheed Al Enezi ◽  
mahesh sounderrajan ◽  
Mishary Najeeb Al-Mudhaf ◽  
...  
Keyword(s):  
Case History ◽  
Gas Well ◽  
History Of ◽  
Sour Gas
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