Methionine Adenosyltransferase Genes in Liver Health and Disease

2014 ◽  
pp. 124-145
Keyword(s):  
Methionine Adenosyltransferase ◽  
Liver Health ◽  
Health And Disease

scholarly journals Role of Oxidative Stress in Liver Health and Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-2 ◽  
Author(s):  
Pablo Muriel ◽  
Karina R. Gordillo
Keyword(s):  
Oxidative Stress ◽  
Liver Health ◽  
Health And Disease

scholarly journals MicroRNAs in Liver Health and Disease

2013 ◽  
Vol 1 (1) ◽  
pp. 53-62 ◽  
Author(s):  
Shu-hao Hsu ◽  
Kalpana Ghoshal
Keyword(s):  
Liver Health ◽  
Health And Disease

Hepatic Metabolism in Liver Health and Disease

2017 ◽  
pp. 391-400 ◽  
Author(s):  
X. Liu ◽  
H. Wang ◽  
X. Liang ◽  
M.S. Roberts
Keyword(s):  
Hepatic Metabolism ◽  
Liver Health ◽  
Health And Disease

One-Carbon Metabolism in Liver Health and Disease

2017 ◽  
pp. 761-765 ◽  
Author(s):  
J.M. Mato ◽  
M.L. Martínez-Chantar ◽  
M. Noureddin ◽  
S.C. Lu
Keyword(s):  
Carbon Metabolism ◽  
Liver Health ◽  
Health And Disease ◽  
One Carbon Metabolism

scholarly journals Role of cAMP and phosphodiesterase signaling in liver health and disease

2018 ◽  
Vol 49 ◽  
pp. 105-115 ◽  
Author(s):  
Banrida Wahlang ◽  
Craig McClain ◽  
Shirish Barve ◽  
Leila Gobejishvili
Keyword(s):  
Liver Health ◽  
Health And Disease

scholarly journals Hydrogen Sulfide as a Novel Regulatory Factor in Liver Health and Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Dong-Dong Wu ◽  
Da-Yong Wang ◽  
Hui-Min Li ◽  
Jian-Cheng Guo ◽  
Shao-Feng Duan ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Regulatory Factor ◽  
Hepatic Ischemia ◽  
Nonalcoholic Fatty Liver ◽  
Glucose And Lipid Metabolism ◽  
Liver Health ◽  
Health And Disease ◽  
Hepatic Ischemia Reperfusion

Hydrogen sulfide (H2S), a colorless gas smelling of rotten egg, has long been recognized as a toxic gas and environment pollutant. However, increasing evidence suggests that H2S acts as a novel gasotransmitter and plays important roles in a variety of physiological and pathological processes in mammals. H2S is involved in many hepatic functions, including the regulation of oxidative stress, glucose and lipid metabolism, vasculature, mitochondrial function, differentiation, and circadian rhythm. In addition, H2S contributes to the pathogenesis and treatment of a number of liver diseases, such as hepatic fibrosis, liver cirrhosis, liver cancer, hepatic ischemia/reperfusion injury, nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, hepatotoxicity, and acute liver failure. In this review, the biosynthesis and metabolism of H2S in the liver are summarized and the role and mechanism of H2S in liver health and disease are further discussed.

Role of Toll-like receptors in liver health and disease

2011 ◽  
Vol 121 (10) ◽  
pp. 415-426 ◽  
Author(s):  
Ruth Broering ◽  
Mengji Lu ◽  
Joerg F. Schlaak
Keyword(s):  
Immune System ◽  
Liver Disease ◽  
Innate Immune System ◽  
Innate Immune ◽  
Toll Like Receptors ◽  
Evolutionarily Conserved ◽  
Liver Health ◽  
Health And Disease ◽  
Molecular Patterns

TLRs (Toll-like receptors), as evolutionarily conserved germline-encoded pattern recognition receptors, have a crucial role in early host defence by recognizing so-called PAMPs (pathogen-associated molecular patterns) and may serve as an important link between innate and adaptive immunity. In the liver, TLRs play an important role in the wound healing and regeneration processes, but they are also involved in the pathogenesis and progression of various inflammatory liver diseases, including autoimmune liver disease, alcoholic liver disease, non-alcoholic steatohepatitis, fibrogenesis, and chronic HBV (hepatitis B virus) and HCV (hepatitis C virus) infection. Hepatitis viruses have developed different evading strategies to subvert the innate immune system. Thus recent studies have suggested that TLR-based therapies may represent a promising approach in the treatment in viral hepatitis. The present review focuses on the role of the local innate immune system, and TLRs in particular, in the liver.

Sinusoids in human liver: Health and disease

1990 ◽  
Vol 11 (1) ◽  
pp. 131
Author(s):  
John A. Summerfield
Keyword(s):  
Human Liver ◽  
Liver Health ◽  
Health And Disease
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