2008 ◽  
Vol 19 (30) ◽  
pp. 305101 ◽  
Author(s):  
J A Dagata ◽  
N Farkas ◽  
C L Dennis ◽  
R D Shull ◽  
V A Hackley ◽  
...  

Author(s):  
Saikumar D ◽  
Leela Prasanna J

The Lipid-based drug delivery system is extensively reported within the literature for the enhancing drug solubility, permeability, and bioavailability. A considerable majority of novel pharmacologically active constituents produced in recent drug discovery programs are lipophilic and poorly soluble, posing a significant problem for pharmaceutical researchers enhancing the oral bioavailability of such drug molecules. Self-nano emulsifying drug delivery systems (SNEDDS), are the viable oil-based approaches for drugs that exhibit low dissolution rate and inadequate absorption. Ever since the progress of SNEDDS, researchers have been focusing on the challenges of BCS Class II and Class IV Drugs for enhancing water Solubility of poorly water-soluble drugs. SNEDDS is a Validate method for enhancing the solubility and bioavailability of lipophilic compounds. It’s the isotropic mixture of oil, surfactant, co-surfactant molecules and it also containing co-solvent molecule. which spontaneously form oil-in-water nano emulsion of approximately 200 nm or less in size upon dilution with water under gentle stirring. It’s Drug delivery system Which possess thermodynamically and kinetically stability. The physicochemical properties, drug solubilization capacity considerably regulates the selection of the SNEDDS components. The compositions of the SNEDDS are often optimized with the assistance of phase diagrams. Further to optimize SNEDDS can be done with the help of statistical experimental design. It’s a Novel drug delivery system which is applicable for the parenteral, Ophthalmic, intranasal and cosmetic drug delivery system. And therefore, the present review describes Preparation, components, mechanism of self-Nano emulsification, biopharmaceutical aspects, characterization methods and applications of Selfnanoemulsifying drug delivery system (SNEDDS).


Drug Delivery ◽  
2014 ◽  
pp. 1-10 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Yuxin Liu ◽  
Yanfei Luo ◽  
Qing Yao ◽  
Yue Zhong ◽  
...  

Langmuir ◽  
2013 ◽  
Vol 29 (32) ◽  
pp. 10205-10212 ◽  
Author(s):  
Rondes F. Silva ◽  
Daniele R. Araújo ◽  
Emerson R. Silva ◽  
Rômulo A. Ando ◽  
Wendel A. Alves

Energies ◽  
2020 ◽  
Vol 13 (22) ◽  
pp. 6045
Author(s):  
Petru Cotfas ◽  
Daniel Cotfas

Finding new sustainable energy sources or improving the efficiencies of the existing ones represents a very important research and development direction. The hybridization approach is one solution for increasing the efficiency of the existing energy sources. In the case of photovoltaic technology, the hybridization of the photovoltaic panels (PV) with thermoelectric generators (TEGs) has become a more interesting solution for the research community in the last decade. Thus, a comprehensive review of the characterization methods and instruments used in PV-TEG hybrid system study represents the objective of this work. PV and TEG equivalent circuits are presented. The instruments and software applications used for the measurements and simulations are presented and analyzed. The analysis of the literature reveals that there are many papers that offer partial or no information about the instruments used or about the measurement quality (accuracies, uncertainties, etc.). In hybrid system modeling, the preferred software applications are MATLAB (MathWorks, Natick, MA, USA) and COMSOL Multiphysics (Comsol, Burlington, MA, USA), while for experimental studies based on computers, LabVIEW (NI, Austin, TX, USA) is preferred. This review work could be interesting for researchers and engineers who are interested in finding solutions for characterizing or monitoring hybrid system components, but it is not limited to these.


2015 ◽  
Vol 42 (7) ◽  
pp. 1165-1173 ◽  
Author(s):  
Gabriela Hädrich ◽  
Samantha Oliveira Monteiro ◽  
Marisa Raquel Rodrigues ◽  
Vânia Rodrigues de Lima ◽  
Jean-Luc Putaux ◽  
...  

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