Nanoengineered Magnetic Field-Induced Targeted Drug Delivery System With Stimuli-Responsive Release

2014 ◽  
pp. 344-360
Author(s):  
R Misra
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Stimuli Responsive ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

Design and Electromagnetic FEM Analysis of a High Gradient Magnet for the Magnetic Targeted Drug Delivery System

2013 ◽  
Vol 753-755 ◽  
pp. 995-1001
Author(s):  
Rui Lin Zhang ◽  
Jie Feng ◽  
Ya Nan Qu ◽  
Ping Geng ◽  
Shou Liang Qi
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Open Circuit ◽  
Experimental Result ◽  
High Gradient ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

Magnetic targeted-drug delivery system (MTDs) works as a promising cancer treatment approach, and is entering the mainstream. It applies an external magnetic field to attract and guide the magnetic nanoparticles (MNPs) carrying treatment agent and targeted antibodies to the lesion region. Its key factor is the high gradient magnet. Here three types of magnets are proposed, i.e., open circuit magnet, close circuit magnet with planar poles, and close circuit magnet with concave-convex poles. And then their magnet field distributions are calculated through the finite element method (FEM). The simulation results are compared with each other and the measurement of Gauss Meter for the manufactured magnet, and the primary experimental result is also reported. It is found the closed magnet circuit with concave-convex poles shows about 2.0 and 1.2 times higher magnetic field intensity (H) than the open magnet circuit and the close magnet circuit with planar poles, respectively. Most important is it owns largest Grad (H) (1.0 e6 A/m2) among three magnets. The simulation agrees well with the measurement, and the primary experimental results also show the magnet can attract MNPs efficiently. Hence the calculation enables provide with credible input for the further trajectory simulation for MNPs.

Corrigendum to: Establishment and In Vitro Evaluation of Porous Ion-Responsive Targeted Drug Delivery System. Protein & Peptide Letters, volume 27(11), (2020).

2021 ◽  
Vol 28 (3) ◽  
pp. 359-359
Author(s):  
Hongfei Liu ◽  
Jie Zhu ◽  
Pengyue Bao ◽  
Yueping Ding ◽  
Jiapeng Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Electronic Version ◽  
In Vitro Evaluation ◽  
Corrected Version ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

The authors are regretful for submitting and approving the publication of incorrect Figure 4 in this article. Below is the corrected version along with the revised caption. The electronic version of the article has already been corrected.

scholarly journals A simple synthesis of a targeted drug delivery system with enhanced cytotoxicity

2011 ◽  
Vol 47 (30) ◽  
pp. 8530 ◽  
Author(s):  
Sanjib Bhattacharyya ◽  
Maria Gonzalez ◽  
J. David Robertson ◽  
Resham Bhattacharya ◽  
Priyabrata Mukherjee
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Simple Synthesis ◽  
Targeted Drug ◽  
Targeted Drug Delivery System
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