In Vivo Confocal Microscopy: Imaging of the Ocular Surface

2014 ◽  
pp. 374-413
Keyword(s):  
Confocal Microscopy ◽  
Ocular Surface ◽  
In Vivo Confocal Microscopy ◽  
Microscopy Imaging ◽  
Confocal Microscopy Imaging

IN VIVO CONFOCAL MICROSCOPY FOR STUDYING CORNEAL DISEASES/CONDITIONS ASSOCIATED WITH CORNEAL NERVE DAMAGE AND OCULAR SURFACE DISEASE.

Cornea ◽  
2000 ◽  
Vol 19 (Supplement 2) ◽  
pp. S131
Author(s):  
T Tervo ◽  
T U Valle ◽  
J AO Moilanen ◽  
M E Rosenberg ◽  
I SJ Tuominen ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Ocular Surface ◽  
Nerve Damage ◽  
Ocular Surface Disease ◽  
In Vivo Confocal Microscopy ◽  
Corneal Nerve

In Vivo Confocal Microscopy of the Ocular Surface

2006 ◽  
Vol 4 (2) ◽  
pp. 81-93 ◽  
Author(s):  
Andrey Zhivov ◽  
Oliver Stachs ◽  
Robert Kraak ◽  
Joachim Stave ◽  
Rudolf F. Guthoff
Keyword(s):  
Confocal Microscopy ◽  
Ocular Surface ◽  
In Vivo Confocal Microscopy

scholarly journals Effect of Autologous Serum Eye Drops in Patients with Sjögren Syndrome-related Dry Eye: Clinical and In Vivo Confocal Microscopy Evaluation of the Ocular Surface

In Vivo ◽  
2016 ◽  
Vol 30 (6) ◽  
pp. 931-938 ◽  
Author(s):  
FRANCESCO SEMERARO ◽  
ELIANA FORBICE ◽  
GIUSEPPE NASCIMBENI ◽  
MARCO TAGLIETTI ◽  
VITO ROMANO ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Dry Eye ◽  
Ocular Surface ◽  
Sjögren Syndrome ◽  
Autologous Serum ◽  
Sjogren Syndrome ◽  
Eye Drops ◽  
In Vivo Confocal Microscopy ◽  
Serum Eye Drops

UV damage of the anterior ocular surface – microstructural evidence by in vivo confocal microscopy

2018 ◽  
Vol 41 (6) ◽  
pp. 482-488 ◽  
Author(s):  
Christina N. Grupcheva ◽  
Dimitar I. Grupchev ◽  
Mladena N. Radeva ◽  
Elitsa G. Hristova
Keyword(s):  
Confocal Microscopy ◽  
Ocular Surface ◽  
In Vivo Confocal Microscopy ◽  
Uv Damage

In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: Consensus terminology glossary and illustrative images

2007 ◽  
Vol 57 (4) ◽  
pp. 644-658 ◽  
Author(s):  
Alon Scope ◽  
Cristiane Benvenuto-Andrade ◽  
Anna-Liza C. Agero ◽  
Josep Malvehy ◽  
Susana Puig ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Skin Lesions ◽  
Reflectance Confocal Microscopy ◽  
Microscopy Imaging ◽  
Confocal Microscopy Imaging

scholarly journals An in vivo confocal microscopy study of corneal changes in patients with systemic sclerosis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eszter Szalai ◽  
Gabriella Szucs ◽  
Szilvia Szamosi ◽  
Zsuzsa Aszalos ◽  
Ildiko Afra ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Confocal Microscopy ◽  
Ocular Surface ◽  
Healthy Subjects ◽  
Ocular Surface Disease ◽  
Nerve Plexus ◽  
In Vivo Confocal Microscopy ◽  
Software Analysis ◽  
Subbasal Nerve Plexus

AbstractTo investigate corneal microstructure of systemic sclerosis (SSc) patients using in vivo confocal microscopy (IVCM). 33 patients with SSc and 30 age-matched healthy subjects were recruited. All participants underwent comprehensive ophthalmic examination including IVCM (Heidelberg Retina Tomograph III, Heidelberg Engineering GmbH, Heidelberg, Germany) and ocular surface evaluation. Subbasal nerve plexus morphology was investigated using automated software analysis (ACCMetrics V3; University of Manchester, Manchester, UK). Keratocyte cell densities in the anterior stroma were significantly lower in patients with SSc compared to controls (P < 0.0001). In 7 SSc patients no keratocyte nuclei were identified in the anterior stroma and in most patients scattered hyperreflective punctate material were observed in the anterior stroma. Significantly lower subbasal nerve fiber parameters were found in patients with SSc compared to healthy subjects (P < 0.05). There were no significant correlations between the duration of SSc and any of the corneal cell density values. Tear break-up time values (4.82 ± 3.15 s) and Ocular Surface Disease Index scores (33.27 ± 30.11) were abnormal, Schirmer values (6.78 ± 5.82 mm) were borderline in SSc patients. In SSc, corneal morphological changes and accumulation of punctate material in the stroma was detected with confocal microscopy. Severe ocular surface disease was observed in SSc patients with significant impairment in subbasal nerve plexus morphology resembling peripheral neuropathy.

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