Metalloenzymes: Relevance in Biological Systems and Potential Applications

2014 ◽  
pp. 262-281
Keyword(s):  
Biological Systems ◽  
Potential Applications

Fluorescence chemosensors for hydrogen sulfide detection in biological systems

The Analyst ◽  
2015 ◽  
Vol 140 (6) ◽  
pp. 1772-1786 ◽  
Author(s):  
Zhi Guo ◽  
Guiqiu Chen ◽  
Guangming Zeng ◽  
Zhongwu Li ◽  
Anwei Chen ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Biological Systems ◽  
Sulfate Reducing Bacteria ◽  
Fluorescence Sensing ◽  
Sulfate Reducing ◽  
Potential Applications ◽  
Reducing Bacteria

The development of H2S fluorescence-sensing strategies and their potential applications in the determination of sulfate-reducing bacteria activity.

scholarly journals Binding abilities of polyaminocyclodextrins: polarimetric investigations and biological assays

2017 ◽  
Vol 13 ◽  
pp. 2751-2763 ◽  
Author(s):  
Marco Russo ◽  
Daniele La Corte ◽  
Annalisa Pisciotta ◽  
Serena Riela ◽  
Rosa Alduina ◽  
...  
Keyword(s):  
Sodium Alginate ◽  
Cellular Uptake ◽  
Biological Systems ◽  
Direct Reaction ◽  
Coulomb Interactions ◽  
Binding Properties ◽  
Biological Assays ◽  
Potential Applications

Three polyaminocyclodextrin materials, obtained by direct reaction between heptakis(6-deoxy-6-iodo)-β-cyclodextrin and the proper linear polyamines, were investigated for their binding properties, in order to assess their potential applications in biological systems, such as vectors for simultaneous drug and gene cellular uptake or alternatively for the protection of macromolecules. In particular, we exploited polarimetry to test their interaction with some model p-nitroaniline derivatives, chosen as probe guests. The data obtained indicate that binding inside the host cavity is mainly affected by interplay between Coulomb interactions and conformational restraints. Moreover, simultaneous interaction of the cationic polyamine pendant bush at the primary rim was positively assessed. Insights on quantitative aspects of the interaction between our materials and polyanions were investigated by studying the binding with sodium alginate. Finally, the complexation abilities of the same materials towards polynucleotides were assessed by studying their interaction with the model plasmid pUC19. Our results positively highlight the ability of our materials to exploit both the cavity and the polycationic branches, thus functioning as bimodal ligands.

Adsorption potential of nanocomposites for the removal of toxins in healthcare

2020 ◽  
Vol 16 ◽  
Author(s):  
Pravin Shende ◽  
Nikita P. Devlekar
Keyword(s):  
Heavy Metals ◽  
Human Health ◽  
Industrial Wastewater ◽  
Biological Systems ◽  
High Surface ◽  
Volume Ratio ◽  
Cost Effective ◽  
Isotherm Models ◽  
Potential Applications ◽  
Enhanced Adsorption

: Industrial wastewater is one of the by-products of several industries and it consists of water that requires treatment before it is discharged in water bodies. The presence of toxins in wastewater such as dyes and heavy metals is hazardous to human health and requires effective removal to reduce environmental pollution. Industrial wastewater treatment has become a global concern in healthcare and environment leading to the development of various technologies for the removal of toxins from wastewater. Various processes and technologies such as advanced oxidation processes, adsorption and membrane technology show potential in treating industrial wastewater. Another source of toxins in the form of pesticides is harmful to human health leading to severe health problems. Nanocomposites show potential as efficient adsorbents for the removal of toxins owing to the enhanced adsorption capacity, promising physicochemical properties and high surface-to-volume ratio due to nanoscale dimension. Nanocomposites are cost effective and efficient nanoadsorbents for the removal of various toxins. This review focuses on the potential applications of nanocomposites as adsorbents for the removal of toxins like dyes, heavy metals and pesticides from wastewater and biological systems. The use of nanocomposites as efficient adsorbents in the removal of toxins, various isotherm models and adsorption kinetics applied in the mechanism of adsorption are also discussed in the article. In the near future, nanocomposites may provide a simple, economical and efficient adsorption system for the removal of toxins from wastewater and biological systems.

Biochemical Processing of Materials: A Review

1994 ◽  
Vol 346 ◽  
Author(s):  
Larry L. Hench
Keyword(s):  
Molecular Orbital ◽  
Materials Science ◽  
Biological Systems ◽  
Nanometer Scale ◽  
List Type ◽  
Type Number ◽  
Hierarchical Processing ◽  
Stereochemical Control ◽  
Potential Applications ◽  
Potential Use

ABSTRACTMany biological systems have evolved means of controlling the architecture of inorganic-organic composites at a nanometer scale. The principles of biochemistry and materials science underlying the potential use of biochemical processing to develop new molecularly tailored materials are discussed, with emphasis on:methods of stereochemical control of the organic-inorganic interface,genetic and enzymic control of biosynthesis and biomineralization,molecular orbital modelling of bio organic-inorganic interfaces,barriers and limitations of biomimetic and hierarchical processing,examples of unique materials made with biochemical processing.needs and potential applications in human prostheses.

Evaluation of Biological Deployable Systems

2005 ◽  
Vol 20 (4) ◽  
pp. 189-200 ◽  
Author(s):  
Caroline Hachem ◽  
Eyal Karni ◽  
Ariel Hanaor
Keyword(s):  
Structural Characteristics ◽  
Biological Systems ◽  
Structural Systems ◽  
Deployable Structures ◽  
Insect Wings ◽  
Potential Applications ◽  
Biological Organisms

The paper presents a survey of deployable structural systems found in some biological organisms. Four biological systems are presented and analysed in terms of their morphology, kinematics and structural characteristics. This presentation is followed by an evaluation of the similarity of the biological systems with existing deployable structures and of potential applications. The four biological systems surveyed are two types of insect wings – Coleoptera (beetles) and locust; locomotion of the earthworm; and the jaw of the egg eater snake ( Dasypeltis). These systems represent a diversity of deployable mechanisms. The paper concludes by associating the surveyed and other biological systems with known deployable structural systems such as: folded plates, tensioned membrane, pneumatic tubes ( pneus) and structures composed of articulated rigid members.

CYTOTOXICITY EVALUATIONS OF FLUORESCENT CARBON NANOPARTICLES

Nano LIFE ◽  
2010 ◽  
Vol 01 (01n02) ◽  
pp. 153-161 ◽  
Author(s):  
JIA-HUI LIU ◽  
PARAMBATH ANILKUMAR ◽  
LI CAO ◽  
XIN WANG ◽  
SHENG-TAO YANG ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Carbon Nanoparticles ◽  
Biological Systems ◽  
Imaging Agents ◽  
Fluorescent Nanoparticles ◽  
Cytotoxic Effects ◽  
Potential Applications ◽  
Carbon Core ◽  
Fluorescent Carbon Nanoparticles ◽  
Fluorescence Markers

Fluorescent nanoparticles have received much attention for their potential applications in biology and medicine, such as uses as fluorescence markers or imaging agents. Recently, surface-passivated carbon nanoparticles or "carbon dots" were demonstrated to be brightly fluorescent, thus representing a new platform for nanoscale fluorescent agents. For targeted bioapplications of carbon dots, an understanding of their toxicity behavior is necessary, including issues on potential defunctionalization of the dots in biological systems that might result in the exposure of the nanoscale carbon core. In this work, we performed cytotoxicity evaluations on both precursor carbon nanoparticles and carbon dots, from which the results suggested no significant cytotoxic effects.

scholarly journals Microfluidic Synthesis and Analysis of Bioinspired Structures Based on CaCO3 for Potential Applications as Drug Delivery Carriers

Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 139
Author(s):  
Ekaterina V. Lengert ◽  
Daria B. Trushina ◽  
Mikhail Soldatov ◽  
Alexey V. Ermakov
Keyword(s):  
Drug Delivery ◽  
Calcium Carbonate ◽  
Biological Systems ◽  
Shell Structures ◽  
Advanced Materials ◽  
Core Shell ◽  
Synthesis Parameters ◽  
Potential Applications ◽  
New Strategies

Naturally inspired biomaterials such as calcium carbonate, produced in biological systems under specific conditions, exhibit superior properties that are difficult to reproduce in a laboratory. The emergence of microfluidic technologies provides an effective approach for the synthesis of such materials, which increases the interest of researchers in the creation and investigation of crystallization processes. Besides accurate tuning of the synthesis parameters, microfluidic technologies also enable an analysis of the process in situ with a range of methods. Understanding the mechanisms behind the microfluidic biomineralization processes could open a venue for new strategies in the development of advanced materials. In this review, we summarize recent advances in microfluidic synthesis and analysis of CaCO3-based bioinspired nano- and microparticles as well as core-shell structures on its basis. Particular attention is given to the application of calcium carbonate particles for drug delivery.

scholarly journals BIONICS APLIED IN PRODUCT DEVELOPMENT

2010 ◽  
Vol 10 (2) ◽  
pp. 263
Author(s):  
Wiliam Jeremias dos Santos
Keyword(s):  
Product Development ◽  
Biological Systems ◽  
Design Concepts ◽  
Potential Applications

In the recent years seems to be increasing the interest of engineers in the nature design concepts, it is because based biological systems and elements from nature we can find technological solutions to improve products and process. In summary, it is bionics. In this paper are presented bionics definition and concepts, its potential applications and finally, the methodology to apply bionics in the development of a product.

scholarly journals Medical contrast media as possible tools for SAXS contrast variation

IUCrJ ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 521-525 ◽  
Author(s):  
Frank Gabel ◽  
Sylvain Engilberge ◽  
Javier Pérez ◽  
Eric Girard
Keyword(s):  
Contrast Agents ◽  
Electron Density ◽  
Soft Matter ◽  
Structural Information ◽  
Biological Systems ◽  
Electron Density Profile ◽  
Contrast Variation ◽  
Electron Densities ◽  
Saxs Data ◽  
Potential Applications

Small-angle X-ray scattering (SAXS) is increasingly used to extract structural information from a multitude of soft-matter and biological systems in aqueous solution, including polymers, detergents, lipids, colloids, proteins and RNA/DNA. When SAXS data are recorded at multiple contrasts, i.e. at different electron densities of the solvent, the internal electron-density profile of solubilized molecular systems can be probed. However, contrast-variation SAXS has been limited by the range of electron densities available by conventional agents such as sugars, glycerol and salt, and by the fact that many soft-matter and biological systems are modified in their presence. Here we present a pioneering SAXS contrast-variation study on DDM (n-dodecyl-β-D-maltopyranoside) micelles by using two highly electron-rich contrast agents from biomedical imaging which belong to the families of gadolinium-based and iodinated molecules. The two agents, Gd-HPDO3A and iohexol, were allowed to attain modifications of the solvent electron density that are 50 to 100% higher than those obtained for sucrose, and are located between the electron densities of proteins and RNA/DNA. In the case of Gd-HPDO3A, an analysis of the internal micellar structure was possible and compared with results obtained with sucrose. In conclusion, medical contrast agents represent a promising class of molecules for SAXS contrast-variation experiments with potential applications for numerous soft-matter and biological systems, including membrane proteins and protein–RNA/DNA complexes.

scholarly journals The Role of Micro Vortex in the Environmental and Biological Processes

2020 ◽  
Author(s):  
Benjamin Oyegbile ◽  
Brian Oyegbile ◽  
Guven Akdogan
Keyword(s):  
Turbulent Flows ◽  
Vortex Dynamics ◽  
Biological Systems ◽  
Particle Interaction ◽  
Short Review ◽  
Liquid Suspension ◽  
Potential Applications ◽  
Complex Fluid ◽  
Solid Liquid

This work presents a short review of the theoretical developments in the application of vortex dynamics to the processing of environmental and biological systems. The mechanisms of complex fluid-particle interaction in vortex dominated and non-vortex dominated flows are briefly discussed from theoretical and practical perspectives. Micro vortex propagation, characteristics and their various applications in environmental process engineering are briefly discussed. Several existing and potential applications of vortex dynamics in turbulent flows are highlighted and as well as the knowledge gaps in the current understanding of turbulence phenomenon with respect to its applications in the processing of solid-liquid suspension and biological systems.

Sign in / Sign up

Export Citation Format

Share Document