Diverse Roles of Angiotensin Receptor Intracellular Signaling Pathways in the Control of Water and Salt Intake

2013 ◽  
pp. 53-66 ◽  
Author(s):  
Derek Daniels
Keyword(s):  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Salt Intake ◽  
Angiotensin Receptor ◽  
Intracellular Signaling Pathways

scholarly journals Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor.

1994 ◽  
Vol 269 (18) ◽  
pp. 13162-13166
Author(s):  
Y. Konda ◽  
I. Gantz ◽  
J. DelValle ◽  
Y. Shimoto ◽  
H. Miwa ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Intracellular Signaling Pathways

scholarly journals Extracellular matrix in cardiovascular pathophysiology

2018 ◽  
Vol 315 (6) ◽  
pp. H1687-H1690 ◽  
Author(s):  
Maria Bloksgaard ◽  
Merry Lindsey ◽  
Luis A. Martinez-Lemus
Keyword(s):  
Extracellular Matrix ◽  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Physical And Mechanical Properties ◽  
Disease Development ◽  
Cardiovascular Development ◽  
Intracellular Signaling Pathways ◽  
Circulatory Physiology ◽  
Activate Cell ◽  
Cell Signaling Pathways

The extracellular matrix (ECM) actively participates in diverse aspects of cardiovascular development and physiology as well as during disease development and progression. ECM roles are determined by its physical and mechanical properties and by its capacity to both release bioactive signals and activate cell signaling pathways. The ECM serves as a storage depot for a wide variety of molecules released in response to injury or with aging. Indeed, there is a plethora of examples describing how cells react to or modify ECM stiffness, how cells initiate intracellular signaling pathways, and how cells respond to the ECM. This Perspectives article reviews the contributions of 21 articles published in the American Journal of Physiology-Heart and Circulatory Physiology in response to a Call for Papers on this topic. Here, we summarize the contributions of these studies focused on the cardiac and vascular ECM. We highlight the translational importance of these studies and conclude that the ECM is a critical component of both the heart and vasculature. Readers are urged to examine and learn from this special Call for Papers.

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