Design and Assessment Principles of Semiconductor Flat-Panel Detector-Based X-Ray Micro-CT Systems for Small-Animal Imaging

2017 ◽  
pp. 109-146 ◽  
Author(s):  
A. Sisniega ◽  
J.J. Vaquero ◽  
M. Desco
Keyword(s):  
Small Animal Imaging ◽  
Small Animal ◽  
Micro Ct ◽  
Flat Panel ◽  
X Ray ◽  
Flat Panel Detector ◽  
Animal Imaging

A flat-panel detector based micro-CT system: performance evaluation for small-animal imaging

2003 ◽  
Vol 48 (24) ◽  
pp. 4173-4185 ◽  
Author(s):  
Sang Chul Lee ◽  
Ho Kyung Kim ◽  
In Kon Chun ◽  
Myung Hye Cho ◽  
Soo Yeol Lee ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
System Performance ◽  
Small Animal Imaging ◽  
Small Animal ◽  
Micro Ct ◽  
Flat Panel ◽  
Flat Panel Detector ◽  
Animal Imaging ◽  
Ct System ◽  
System Performance Evaluation

scholarly journals Comparative study of two flat-panel X-ray detectors applied to small-animal imaging cone-beam micro-CT

2008 ◽  
Author(s):  
Alejandro Sisniega ◽  
Juan Jose Vaquero ◽  
Eduardo Lage ◽  
Alvaro de Carlos ◽  
Jose L. Villena ◽  
...  
Keyword(s):  
Comparative Study ◽  
Small Animal Imaging ◽  
Small Animal ◽  
Cone Beam ◽  
Micro Ct ◽  
Flat Panel ◽  
X Ray ◽  
Animal Imaging

SU-GG-J-16: A Physiologically Gated Micro-CT Scanner for Dynamic Small Animal Imaging Based On a Carbon Nanotube X-Ray Source

2008 ◽  
Vol 35 (6Part5) ◽  
pp. 2682-2682
Author(s):  
G Cao ◽  
R Peng ◽  
Y Lee ◽  
R Rajaram ◽  
X Calderon-Colon ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Small Animal Imaging ◽  
Small Animal ◽  
Micro Ct ◽  
Ct Scanner ◽  
X Ray ◽  
Animal Imaging

scholarly journals Cone Beam Micro-CT System for Small Animal Imaging and Performance Evaluation

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
Shouping Zhu ◽  
Jie Tian ◽  
Guorui Yan ◽  
Chenghu Qin ◽  
Jinchao Feng
Keyword(s):  
Spatial Resolution ◽  
Small Animal Imaging ◽  
Small Animal ◽  
Whole Body ◽  
Cone Beam ◽  
Large Field ◽  
Micro Ct ◽  
X Ray ◽  
Animal Imaging ◽  
Ct System

A prototype cone-beam micro-CT system for small animal imaging has been developed by our group recently, which consists of a microfocus X-ray source, a three-dimensional programmable stage with object holder, and a flat-panel X-ray detector. It has a large field of view (FOV), which can acquire the whole body imaging of a normal-size mouse in a single scan which usually takes about several minutes or tens of minutes. FDK method is adopted for 3D reconstruction with Graphics Processing Unit (GPU) acceleration. In order to reconstruct images with high spatial resolution and low artifacts, raw data preprocessing and geometry calibration are implemented before reconstruction. A method which utilizes a wire phantom to estimate the residual horizontal offset of the detector is proposed, and 1D point spread function is used to assess the performance of geometric calibration quantitatively. System spatial resolution, image uniformity and noise, and low contrast resolution have been studied. Mouse images with and without contrast agent are illuminated in this paper. Experimental results show that the system is suitable for small animal imaging and is adequate to provide high-resolution anatomic information for bioluminescence tomography to build a dual modality system.

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