Cancer Detection and Biosensing Applications with Quantum Dots

Luminescence ◽  
2013 ◽  
pp. 305-336
Keyword(s):  
Quantum Dots ◽  
Cancer Detection

A Universal Quantum Dots-Aptamer Probe for Efficient Cancer Detection and Targeted Imaging

2012 ◽  
Vol 12 (10) ◽  
pp. 7703-7708 ◽  
Author(s):  
Shuhong Lian ◽  
Pengfei Zhang ◽  
Ping Gong ◽  
Dehong Hu ◽  
Bihua Shi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cancer Detection ◽  
Targeted Imaging ◽  
Universal Quantum ◽  
Aptamer Probe

Nanobiotechnology and Therapeutics

2018 ◽  
pp. 75-99
Author(s):  
Vikrant
Keyword(s):  
Gene Therapy ◽  
Quantum Dots ◽  
Cancer Cells ◽  
Cancer Detection ◽  
Safety Profile ◽  
Crucial Role ◽  
Target Tissue ◽  
Chemotherapeutic Drugs ◽  
Toxic Potential ◽  
Improved Methods

Nanobiotechnology deals with the application of the tools and processes of nanotechnology to build devices for studying and manipulating biological systems. Current approaches of diagnosis and treatment of various diseases, especially cancer have major limitations such as poor sensitivity or specificity and drug toxicities respectively. Novel and improved methods of cancer detection based on nanoparticles are required to be developed. Some of the nanoparticles used for diagnostic purposes are paramagnetic nanoparticles, quantum dots, nanoshells and nanosomes. Drugs with high toxic potential like cancer chemotherapeutic drugs can be given with a better safety profile with the utility of nanotechnology. These can be made to act specifically at the target tissue by active as well as passive means. Simultaneously, other alternative ways of therapy such as heat induced killings of cancer cells by nanoshells and gene therapy are also being developed. Thus, it indicates that nanomedicine in future would play a crucial role in the treatment of human diseases.

Nanobiotechnology and Therapeutics

2017 ◽  
pp. 1-31
Author(s):  
Vikrant
Keyword(s):  
Gene Therapy ◽  
Quantum Dots ◽  
Cancer Cells ◽  
Cancer Detection ◽  
Safety Profile ◽  
Crucial Role ◽  
Target Tissue ◽  
Chemotherapeutic Drugs ◽  
Toxic Potential ◽  
Improved Methods

Nanobiotechnology deals with the application of the tools and processes of nanotechnology to build devices for studying and manipulating biological systems. Current approaches of diagnosis and treatment of various diseases, especially cancer have major limitations such as poor sensitivity or specificity and drug toxicities respectively. Novel and improved methods of cancer detection based on nanoparticles are required to be developed. Some of the nanoparticles used for diagnostic purposes are paramagnetic nanoparticles, quantum dots, nanoshells and nanosomes. Drugs with high toxic potential like cancer chemotherapeutic drugs can be given with a better safety profile with the utility of nanotechnology. These can be made to act specifically at the target tissue by active as well as passive means. Simultaneously, other alternative ways of therapy such as heat induced killings of cancer cells by nanoshells and gene therapy are also being developed. Thus, it indicates that nanomedicine in future would play a crucial role in the treatment of human diseases.

Doped Graphene Quantum Dots for Intracellular Multicolor Imaging and Cancer Detection

2019 ◽  
Vol 5 (9) ◽  
pp. 4671-4682 ◽  
Author(s):  
Elizabeth Campbell ◽  
Md. Tanvir Hasan ◽  
Roberto Gonzalez Rodriguez ◽  
Giridhar R. Akkaraju ◽  
Anton V. Naumov
Keyword(s):  
Quantum Dots ◽  
Cancer Detection ◽  
Graphene Quantum Dots ◽  
Multicolor Imaging ◽  
Doped Graphene

scholarly journals Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

2019 ◽  
Vol 14 (3) ◽  
pp. 365-377 ◽  
Author(s):  
Jayshree Ashree ◽  
Qi Wang ◽  
Yimin Chao
Keyword(s):  
Quantum Dots ◽  
Cancer Detection ◽  
Cancer Diagnosis ◽  
Biomedical Applications ◽  
Biomedical Imaging ◽  
Recent Progress ◽  
Diagnosis And Treatment ◽  
Novel Approach ◽  
Behaviour Study

Abstract Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

scholarly journals Bio-Conjugated Quantum Dots for Cancer Research: Detection and Imaging

2021 ◽  
Vol 11 ◽  
Author(s):  
Zhengyan Liang ◽  
Muhammad Babar Khawar ◽  
Jingyan Liang ◽  
Haibo Sun
Keyword(s):  
Cancer Research ◽  
Quantum Dots ◽  
Cancer Detection ◽  
Light Emission ◽  
Fluorescent Nanoparticles ◽  
Ultrasound Computed Tomography ◽  
Optimal Surface ◽  
Bio Imaging ◽  
Source Excitation ◽  
Sensitivity Specificity

Ultrasound, computed tomography, magnetic resonance, and gamma scintigraphy-based detection and bio-imaging technologies have achieved outstanding breakthroughs in recent years. However, these technologies still encounter several limitations such as insufficient sensitivity, specificity and security that limit their applications in cancer detection and bio-imaging. The semiconductor quantum dots (QDs) are a kind of newly developed fluorescent nanoparticles that have superior fluorescence intensity, strong resistance to photo-bleaching, size-tunable light emission and could produce multiple fluorescent colors under single-source excitation. Furthermore, QDs have optimal surface to link with multiple targets such as antibodies, peptides, and several other small molecules. Thus, QDs might serve as potential, more sensitive and specific methods of detection than conventional methods applied in cancer molecular targeting and bio-imaging. However, many challenges such as cytotoxicity and nonspecific uptake still exist limiting their wider applications. In the present review, we aim to summarize the current applications and challenges of QDs in cancer research mainly focusing on tumor detection, bio-imaging, and provides opinions on how to address these challenges.

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