Thermodynamic Analysis Of Metabolic Pathways

2013 ◽  
pp. 603-626
Author(s):  
Laura Fernandes de Almeida Meirelles ◽  
Andreas Karoly Gombert ◽  
Pedro Alcântara Pessôa Filho

The yeast Saccharomyces cerevisiae is able to oxidize the glucose molecule through the metabolic pathways of fermentation and respiration, storing the released energy in the chemical bonds of the ATP molecule. However, less than half of this energy is used for ATP synthesis, supporting the hypothesis that the cell stores the spare energy in the chemical bonds of other components, in addition to releasing some of the energy in the form of heat. To verify this hypothesis, the present work validated a series of analyzes for the determination of the cell's composition, whether in relation to macromolecular and elemental components or metabolites. These analyzes will be applied in bioreactor cultivations under anaerobiosis or under aerobiosis, allowing to evaluate if the composition of the cells varies in these two conditions.


2001 ◽  
Vol 268 (6) ◽  
pp. 1554-1560 ◽  
Author(s):  
Reinskje Talhout ◽  
Jan B. F. N. Engberts

2010 ◽  
Author(s):  
Sohan Lal ◽  
Kolin Paul ◽  
James Gomes
Keyword(s):  

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
E Vikeved ◽  
R Buonfiglio ◽  
T Kogej ◽  
A Backlund

1965 ◽  
Vol 49 (3) ◽  
pp. 427-435 ◽  
Author(s):  
K. D. Voigt ◽  
J. Tamm ◽  
U. Volkwein ◽  
H. Schedewie

ABSTRACT Pregnenolone-sulphate (400 mg) was perfused through isolated dog livers. The following steroids were isolated in the perfusate: pregnenolone, progesterone, dehydroepiandrosterone, androst-5-ene-diol and the two steroid conjugates, i. e. pregnenolone-sulphate and dehydroepiandrosterone-sulphate. Two »free« steroids and one steroid conjugate could not be characterized. A tentative scheme for the metabolic pathways of pregnenolone-sulphate is presented.


2015 ◽  
Vol 9 (2) ◽  
pp. 190
Author(s):  
Meiriele A. Alvarenga ◽  
Claudia R. Andrade ◽  
Edson L. Zaparoli

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