Therapy of Obstructive and Central Sleep Apnea in Patients with Congestive Heart Failure

Sleep Apnea ◽  
2000 ◽  
pp. 480-513
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Central Sleep Apnea

scholarly journals Nocturnal oxyhemoglobin desaturation during sleep in congestive heart failure patients

2016 ◽  
Vol 29 (3) ◽  
pp. 597-606
Author(s):  
Jéssica Julioti Urbano ◽  
Lilian Nanami Uchiyama ◽  
Anderson Soares Silva ◽  
Roger André Oliveira Peixoto ◽  
Sergio Roberto Nacif ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Pulse Oximetry ◽  
Arterial Oxygen Saturation ◽  
Central Sleep Apnea ◽  
Arterial Oxygen ◽  
Sleep Breathing Disorders ◽  
Breathing Disorders ◽  
Obstructive Sleep

Abstract Introduction: Sleep breathing disorders occur in 45% of patients with heart failure, with 36%-50% manifesting Cheyne-Stokes respiration with central sleep apnea and 12% exhibiting obstructive sleep apnea. Several studies have shown that sleep pathophysiology may negatively affect the cardiovascular system and that cardiac dysfunction alters sleep and respiration. Objective: The aim of this study was to examine oxyhemoglobin desaturation during sleep in patients with congestive heart failure (CHF) using overnight pulse oximetry. Methods: Overnight pulse oximetry was conducted in the patients' homes with wrist pulse oximeters and finger probes that were placed around the forefingers of 15 patients with CHF and ejection fractions less than 50%, who were classified as New York Heart Association functional classes II and III. Results: The patients were divided into two groups. The first group consisted of seven patients with oxyhemoglobin desaturation indices of over 5 events/h, and the second group contained eight patients with oxyhemoglobin desaturation indices of 5 or less events/h. Student's t-tests did not show any significant differences between the groups. The patients' body mass indices correlated positively with the total desaturation episodes and desaturation time less than 90% and correlated negatively with the arterial oxygen saturation nadir. Conclusion: Pulse oximetry monitoring during sleep can be used to detect sleep breathing disorders in stable patients with CHF.

Peripheral and Central Ventilatory Responses in Central Sleep Apnea with and without Congestive Heart Failure

2000 ◽  
Vol 162 (6) ◽  
pp. 2194-2200 ◽  
Author(s):  
PETER SOLIN ◽  
TEANAU ROEBUCK ◽  
DAVID P. JOHNS ◽  
E. HAYDN WALTERS ◽  
MATTHEW T. NAUGHTON
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Central Sleep Apnea ◽  
Ventilatory Responses

Dynamic ventilatory response to CO2 in congestive heart failure patients with and without central sleep apnea

2001 ◽  
Vol 91 (1) ◽  
pp. 408-416 ◽  
Author(s):  
Zbigniew L. Topor ◽  
Linda Johannson ◽  
Jerzy Kasprzyk ◽  
John E. Remmers
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Central Sleep Apnea ◽  
Response Duration ◽  
Open Loop ◽  
Loop Gain ◽  
Loop Dynamics ◽  
Dynamic Gain ◽  
Ventilatory Response To Co2

Nonobstructive (i.e., central) sleep apnea is a major cause of sleep-disordered breathing in patients with stable congestive heart failure (CHF). Although central sleep apnea (CSA) is prevalent in this population, occurring in 40–50% of patients, its pathogenesis is poorly understood. Dynamic loop gain and delay of the chemoreflex response to CO2 was measured during wakefulness in CHF patients with and without CSA by use of a pseudorandom binary CO2 stimulus method. Use of a hyperoxic background minimized responses derived from peripheral chemoreceptors. The closed-loop and open-loop gain, estimated from the impulse response, was three times greater in patients with nocturnal CSA ( n = 9) than in non-CSA patients ( n = 9). Loop dynamics, estimated by the 95% response duration time, did not differ between the two groups of patients. We speculate that an increase in dynamic gain of the central chemoreflex response to CO2 contributes to the genesis of CSA in patients with CHF.

Decreased Exercise Ventilatory Efficiency Is Associated with Central Sleep Apnea in Patients with Congestive Heart Failure

2007 ◽  
Vol 13 (6) ◽  
pp. S91
Author(s):  
Lyle J. Olson ◽  
Virend K. Somers ◽  
Jennifer M. Miller ◽  
Christopher G. Scott ◽  
Michal S. Hoffmann ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Central Sleep Apnea ◽  
Ventilatory Efficiency

Congestive Heart Failure and Central Sleep Apnea

2016 ◽  
Vol 11 (1) ◽  
pp. 127-142 ◽  
Author(s):  
Scott A. Sands ◽  
Robert L. Owens
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Sleep Apnea ◽  
Central Sleep Apnea
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