Shorter Course Antibiotic Therapy (SCAT): Principles, Current Data, and Caveats

2007 ◽  
pp. 337-370
Author(s):  
Donald E. Craven ◽  
Daniel P. McQuillen ◽  
Winnie W. Ooi ◽  
George A. Jacoby ◽  
Efren L. Rael ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Current Data

Changing Trends of Peritonsillar Abscess

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P33-P33
Author(s):  
Tal Marom ◽  
Yehudah Roth ◽  
David Itskoviz ◽  
Udi Cinamon
Keyword(s):  
Antibiotic Therapy ◽  
Medical Center ◽  
Study Data ◽  
Peritonsillar Abscess ◽  
Current Data ◽  
Predisposing Factor ◽  
Acute Tonsillitis ◽  
Changing Trends ◽  
Hospitalization Period ◽  
Population Rate

Objective To assess changes in the characteristics of peritonsillar abscess (PTA). Methods A retrospective cohort study. Data obtained from medical records of patients diagnosed as having a peritonsillar abscess that were treated in a secondary urban medical center over a ten-year period (1998–2007). Results 427 patients, within ages of 3 to 91 years (average 31.6, SD 15.2, median 30) were enrolled. 47 patients (11%) were admitted more than once for PTA. There was no gender, seasonal, or localization predominance. 13 patients (3%) developed PTA complications. 104 patients (24.4%) were 40 years old or older, having a longer hospitalization period, and were more prone to complications. 102 patients (23.9%) did not have acute tonsillitis before PTA evolvement. Smoking was more common among patients than in the general population rate (33% vs 25%), associated with a higher complication. Culture results and antibiotic therapy influence were analyzed for all PTA cases (n=486). In 283 patients (58.2%) developed PTA in spite of a prior antibiotic therapy. Smoking was associated with a higher infection rate by Streptococcus viridans. Conclusions Comparison of current data to earlier reports suggests that PTA has gradually changed its characteristics: affecting older patients, having a more vigorous presentation and a longer course, abscess evolvement without an anteceding tonsillitis, and patients developing PTA in spite of a prior adequate antibiotic therapy. In addition, smoking may be a predisposing factor.

scholarly journals Risks Related to the Use of Non-Steroidal Anti-Inflammatory Drugs in Community-Acquired Pneumonia in Adult and Pediatric Patients

2019 ◽  
Vol 8 (6) ◽  
pp. 786 ◽  
Author(s):  
Guillaume Voiriot ◽  
Quentin Philippot ◽  
Alexandre Elabbadi ◽  
Carole Elbim ◽  
Martin Chalumeau ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Strong Association ◽  
Community Acquired Pneumonia ◽  
Current Data ◽  
Hospital Length Of Stay ◽  
Hospital Referral ◽  
Complicated Course ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Tract Infections

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate symptoms during community-acquired pneumonia (CAP), while neither clinical data nor guidelines encourage this use. Experimental data suggest that NSAIDs impair neutrophil intrinsic functions, their recruitment to the inflammatory site, and the resolution of inflammatory processes after acute pulmonary bacterial challenge. During CAP, numerous observational data collected in hospitalized children, hospitalized adults, and adults admitted to intensive care units (ICUs) support a strong association between pre-hospital NSAID exposure and a delayed hospital referral, a delayed administration of antibiotic therapy, and the occurrence of pleuropulmonary complications, even in the only study that has accounted for a protopathic bias. Other endpoints have been described including a longer duration of antibiotic therapy and a greater hospital length of stay. In all adult series, patients exposed to NSAIDs were younger and had fewer comorbidities. The mechanisms by which NSAID use would entail a complicated course in pneumonia still remain uncertain. The temporal hypothesis and the immunological hypothesis are the two main emerging hypotheses. Current data strongly support an association between NSAID intake during the outpatient treatment of CAP and a complicated course. This should encourage experts and scientific societies to strongly advise against the use of NSAIDs in the management of lower respiratory tract infections.

An Acute Atypical Colitis after Antibiotic Therapy

1962 ◽  
Vol 43 (5) ◽  
pp. 585-587 ◽  
Author(s):  
Herbert N. Harkleroad ◽  
Joseph A. Rinaldo
Keyword(s):  
Antibiotic Therapy

532: Empirical Antibiotic Therapy in the Management of Elevated Serum PSA- A Viable Option?

2006 ◽  
Vol 175 (4S) ◽  
pp. 172-172
Author(s):  
Chee Kwan Ng ◽  
Gerald Y. Tan ◽  
Khai Lee Toh ◽  
Sing Joo Chia ◽  
James K. Tan
Keyword(s):  
Antibiotic Therapy ◽  
Elevated Serum ◽  
Empirical Antibiotic Therapy ◽  
Viable Option

106: Trial of 45 Days of Antibiotic Therapy in Patients with Asymptomatic Biopsy-Proven Prostatitis

2006 ◽  
Vol 175 (4S) ◽  
pp. 34-35
Author(s):  
Jeffrey R. Springer ◽  
M. Scott Wingo ◽  
Thomas E. Keane ◽  
Harry S. Clarke
Keyword(s):  
Antibiotic Therapy

Comments on Current Antibiotic Therapy

1979 ◽  
Vol 12 (2) ◽  
pp. 431-438
Author(s):  
Richard H. Winterbauer
Keyword(s):  
Antibiotic Therapy

Successful Entrepreneurship as Developmental Outcome

2011 ◽  
Vol 16 (3) ◽  
pp. 174-186 ◽  
Author(s):  
Martin Obschonka ◽  
Rainer K. Silbereisen ◽  
Eva Schmitt-Rodermund
Keyword(s):  
Big Five ◽  
Role Models ◽  
Structural Equation ◽  
Current Data ◽  
Equation Modeling ◽  
Authoritative Parenting ◽  
Venture Creation ◽  
Entrepreneurial Success ◽  
Entrepreneurial Skills ◽  
Age Appropriate

Applying a lifespan approach of human development, this study examined pathways to entrepreneurial success by analyzing retrospective and current data. Along the lines of McClelland’s ideas of early entrepreneurship development and Rauch and Frese’s Giessen-Amsterdam model on venture success, we investigated the roles of founders’ adolescent years (early role models, authoritative parenting, and early entrepreneurial competence), personality traits (Big Five pattern), and entrepreneurial skills and growth goals during venture creation. Findings were derived from structural equation modeling studying two comparable samples of founders (N = 531) and nascent founders (N = 100) from Germany. Across both samples, reports on age-appropriate entrepreneurial competence in adolescence and an entrepreneurial Big Five profile predicted entrepreneurial skills during venture creation, which in turn predicted founders’ setting of ambitious growth goals and entrepreneurial success. Early entrepreneurial competence was related to the availability of entrepreneurial role models and authoritative parenting during adolescence as well as to an entrepreneurial Big Five profile. In line with prospective reports on early precursors of entrepreneurship, the findings illuminate the development of entrepreneurship in general and entrepreneurial success in particular over the lifespan, especially with regard to factors relevant in the adolescent years and the interplay with personality across different developmental periods.

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