Surface Modification of High-Strength Interpenetrating Network Hydrogels for Biomedical Device Applications

2013 ◽  
pp. 441-480
Keyword(s):  
Surface Modification ◽  
High Strength ◽  
Interpenetrating Network ◽  
Biomedical Device ◽  
Device Applications

In situ polymerization approach to cellulose–polyacrylamide interpenetrating network hydrogel with high strength and pH-responsive properties

Cellulose ◽  
2018 ◽  
Vol 26 (3) ◽  
pp. 1825-1839 ◽  
Author(s):  
Fengcai Lin ◽  
Xiangchao Lu ◽  
Zi Wang ◽  
Qilin Lu ◽  
Guanfeng Lin ◽  
...  
Keyword(s):  
In Situ Polymerization ◽  
High Strength ◽  
Ph Responsive ◽  
Interpenetrating Network

Effect of the Pore Structure of an Apatite-Fiber Scaffold on the Differentiation of P19.CL6 Cells into Cardiomyocytes

2018 ◽  
Vol 782 ◽  
pp. 116-123
Author(s):  
Yuzuha Ichikawa ◽  
Kei Yasuda ◽  
Masahiro Takahara ◽  
Mamoru Aizawa ◽  
Nobuyuki Kanzawa
Keyword(s):  
Troponin T ◽  
Specific Gene ◽  
Porous Hydroxyapatite ◽  
Spherical Carbon ◽  
Functional Maturation ◽  
Biomedical Device ◽  
Hydroxyapatite Ceramics ◽  
Proliferation And Differentiation ◽  
Device Applications ◽  
Radial Flow Bioreactor

We previously reported that P19.CL6 cells can be cultured in porous hydroxyapatite ceramics prepared by firing green compacts consisting of apatite fibers and spherical carbon beads (150 μm in diameter). Cells cultured for 20 days in an apatite-fiber scaffold (AFS) proliferated and differentiated into cells expressing troponin T, a cardiomyocyte-specific gene, but the expression level was insufficient to support the functional maturation of cells required for biomedical device applications. In this study, we aimed to optimize the internal AFS environment for cardiomyocytes by mixing two sizes (150-and 20-μm) of carbon beads. P19.CL6 cells were cultured in AFS materials comprising different carbon ratios in the presence of alpha-MEM with (AFS+) or without (AFS-) dimethyl sulfoxide (DMSO), and cell growth and gene expression were assessed. We found that AFS(50, 1:1 ratio) is the most suitable scaffold for the proliferation and differentiation of P19.CL6 cells and the addition of DMSO to the culture medium is necessary for differentiation into cardiomyocytes. We also assessed the culture of P19.CL6 cells in AFS in a radial-flow bioreactor for several days.

scholarly journals Synthesis and characterization of a fluorinated S-nitrosothiol as the nitric oxide donor for fluoropolymer-based biomedical device applications

2018 ◽  
Vol 6 (38) ◽  
pp. 6142-6152 ◽  
Author(s):  
Yang Zhou ◽  
Qi Zhang ◽  
Jianfeng Wu ◽  
Chuanwu Xi ◽  
Mark E. Meyerhoff
Keyword(s):  
Nitric Oxide ◽  
Polyvinylidene Fluoride ◽  
Nitric Oxide Donor ◽  
Synthesis And Characterization ◽  
No Donor ◽  
Fluorinated Polymer ◽  
Biomedical Device ◽  
Device Applications

The first nitric oxide (NO) releasing fluorinated polymer was developed via incorporating a new fluorinated NO donor into polyvinylidene fluoride tubing.

scholarly journals PVA/Agar Interpenetrating Network Hydrogel with Fast Healing, High Strength, Antifreeze, and Water Retention

2020 ◽  
Vol 221 (22) ◽  
pp. 2070049
Author(s):  
Xin Han ◽  
Mengyu Li ◽  
Zewen Fan ◽  
Yu Zhang ◽  
Huihui Zhang ◽  
...  
Keyword(s):  
Water Retention ◽  
High Strength ◽  
Interpenetrating Network ◽  
Fast Healing
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