Lateral Pelvic Side-Wall Nodal Involvement in Rectal Cancer

2013 ◽  
pp. 230-235
Keyword(s):  
Rectal Cancer ◽  
Side Wall ◽  
Nodal Involvement

Pelvic side wall nodes in locally advanced rectal cancer as a prognostic indicator.

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 613-613
Author(s):  
Kirsten Elizabeth Jean Laws ◽  
Christina Wilson ◽  
Stephen Harrow
Keyword(s):  
Rectal Cancer ◽  
Overall Survival ◽  
Locally Advanced ◽  
Side Wall ◽  
Distant Metastases ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Pre Treatment ◽  
Long Course ◽  
Patterns Of Recurrence

613 Background: Neoadjuvant long course chemoradiotherapy is a well recognised treatment in locally advanced rectal cancer. Patients with pelvic side wall nodes are often considered for neoadjuvant treatment. We investigated whether pelvic side wall nodes identified on pre-treatment imaging is a poor prognostic factor and whether there are different patterns of recurrence compared to patients without pelvic side wall node involvement. Methods: All patients treated with long course chemoradiotherapy between January 2008 and December 2009 were identified. Patients were excluded if treatment indication was for inoperable disease, postoperative, recurrence, or palliative intent. 231 patients were identified and a retrospective analysis performed investigating patterns of recurrence and survival for patients with pelvic side wall nodes identified on pre-treatment imaging. Results: Kaplan Meier curves are presented showing patients with pelvic side wall nodes identified on pre-treatment imaging appear to have poorer outcomes and overall survival compared with those with only mesorectal nodes or no nodes. Patterns of recurrence are presented, showing patients with pelvic side wall nodes identified on pre-treatment imaging have a non significant trend to increased rates of disease recurrence (local and distal recurrence combined, 45.7% versus 27.9% for pelvic side wall nodes versus no pelvic side wall nodes). Patients with pelvic side wall nodes identified on pre-treatment imaging appear to be more likely to develop distant metastases compared to those patients who have mesorectal nodes or no nodal involvement (37% versus 23%). Conclusions: Our study highlights that patients with pelvic side wall nodes identified on pre-treatment imaging appear to have a trend to poorer overall survival, are more likely to recur and develop distant metastases. These results were not statistically significant, due to the small number of patients, and the data is consequently limited. We intend to further investigate current management strategies for this subgroup of patients, with assessment of radiotherapy treatment plans, current use of integral boosts, and surgical procedures for this subgroup of patients.

scholarly journals Delayed Haemorrhage Following Pelvic Side Wall Excision With Internal Iliac Vessel Resection in Locally Recurrent Rectal Cancer

2020 ◽  
Vol 90 (10) ◽  
pp. 2125-2127
Author(s):  
Jordan M. Hamilton ◽  
Tomas J. Larach ◽  
Alexander G. Heriot ◽  
Satish K. Warrier ◽  
Jacob J. McCormick
Keyword(s):  
Rectal Cancer ◽  
Side Wall ◽  
Recurrent Rectal Cancer ◽  
Iliac Vessel ◽  
Locally Recurrent Rectal Cancer ◽  
Internal Iliac ◽  
Locally Recurrent

scholarly journals Analysis of Risk Factors for Lymph Nodal Involvement in Early Stages of Rectal Cancer: When Can Local Excision Be Considered an Appropriate Treatment? Systematic Review and Meta-Analysis of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandro Carrara ◽  
Daniela Mangiola ◽  
Riccardo Pertile ◽  
Alberta Ricci ◽  
Michele Motter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Local Excision ◽  
Radical Surgery ◽  
Meta Analysis ◽  
Nodal Involvement ◽  
Node Metastasis ◽  
Early Stages

Background. Over the past ten years oncological outcomes achieved by local excision techniques (LETs) as the sole treatment for early stages of rectal cancer (ESRC) have been often disappointing. The reasons for these poor results lie mostly in the high risk of the disease's diffusion to local-regional lymph nodes even in ESRC.Aims. This study aims to find the correct indications for LET in ESRC taking into consideration clinical-pathological features of tumours that may reduce the risk of lymph node metastasis to zero.Methods. Systematic literature review and meta-analysis of casistics of ESRC treated with total mesorectal excision with the aim of identifying risk factors for nodal involvement.Results. The risk of lymph node metastasis is higher inG≥2andT≥2tumours with lymphatic and/or vascular invasion. Other features which have not yet been sufficiently investigated include female gender, TSM stage >1, presence of tumour budding and/or perineural invasion.Conclusions. Results comparable to radical surgery can be achieved by LET only in patients with T1N0G1tumours with low-risk histological features, whereas deeper or more aggressive tumours should be addressed by radical surgery (RS).

Risk factors for nodal involvement in early stage rectal cancer: a new scoring system based in the analysis of 326 cases

2021 ◽  
Author(s):  
Alessandro CARRARA ◽  
Gianmarco GHEZZI ◽  
Federico REICH ◽  
Michele MOTTER ◽  
Riccardo PERTILE ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Scoring System ◽  
Early Stage ◽  
Nodal Involvement ◽  
New Scoring

How to do a robotic lateral pelvic side wall dissection for rectal cancer

2022 ◽  
Author(s):  
William Jiang ◽  
Naradha Lokuhetty ◽  
Helen M. Mohan ◽  
José Tomás Larach ◽  
Peadar Waters ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Side Wall
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