Prevention strategies, early detection and results of education programmes

2003 ◽  
pp. 81-89
Author(s):  
Jason Rivers ◽  
Robert Burton
Keyword(s):  
Early Detection ◽  
Prevention Strategies

scholarly journals Pancreatic Cancer Exposome Profile to Aid Early Detection and Inform Prevention Strategies

2021 ◽  
Vol 10 (8) ◽  
pp. 1665
Author(s):  
Maria J. Monroy-Iglesias ◽  
Saoirse Dolly ◽  
Debashis Sarker ◽  
Kiruthikah Thillai ◽  
Mieke Van Hemelrijck ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Detection ◽  
Immune Responses ◽  
Inflammatory Markers ◽  
Poor Prognosis ◽  
Associated Factors ◽  
Review Of The Literature ◽  
Prevention Strategies ◽  
Factors Influencing ◽  
Detection Strategies

Pancreatic cancer (PCa) is associated with a poor prognosis and high mortality rate. The causes of PCa are not fully elucidated yet, although certain exposome factors have been identified. The exposome is defined as the sum of all environmental factors influencing the occurrence of a disease during a life span. The development of an exposome approach for PCa has the potential to discover new disease-associated factors to better understand the carcinogenesis of PCa and help with early detection strategies. Our systematic review of the literature identified several exposome factors that have been associated with PCa alone and in combination with other exposures. A potential inflammatory signature has been observed among the interaction of several exposures (i.e., smoking, alcohol consumption, diabetes mellitus, obesity, and inflammatory markers) that further increases the incidence and progression of PCa. A large number of exposures have been identified such as genetic, hormonal, microorganism infections and immune responses that warrant further investigation. Future early detection strategies should utilize this information to assess individuals’ risk for PCa.

scholarly journals Seasonal Patterns in Syndromic Surveillance Emergency Department Data due to Respiratory Illnesses

2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Kelly Johnson ◽  
Alecia Alianell ◽  
Rachel Radcliffe
Keyword(s):  
Emergency Department ◽  
South Carolina ◽  
Early Detection ◽  
Syndromic Surveillance ◽  
Seasonal Patterns ◽  
Prevention Strategies ◽  
Respiratory Illnesses ◽  
Seasonal Trends ◽  
Emergency Department Data

This abstract assesses the seasonal trends in respiratory illnesses using South Carolina syndromic surveillance emergency department data. The use of syndromic surveillance emergency department data to track respiratory illnesses is useful for the early detection of illness clusters in a particular area and for the development of prevention strategies in preparation of increases in respiratory illnesses.

scholarly journals A Systematic Review on Cost-effectiveness Studies Evaluating Ovarian Cancer Early Detection and Prevention Strategies

2020 ◽  
Vol 13 (5) ◽  
pp. 429-442
Author(s):  
Gaby Sroczynski ◽  
Artemisa Gogollari ◽  
Felicitas Kuehne ◽  
Lára R. Hallsson ◽  
Martin Widschwendter ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Cancer ◽  
Cost Effectiveness ◽  
Early Detection ◽  
Prevention Strategies ◽  
Cancer Early Detection ◽  
Effectiveness Studies ◽  
Early Detection And Prevention

scholarly journals Cost-Effectiveness of Early Detection and Prevention Strategies for Endometrial Cancer—A Systematic Review

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1874
Author(s):  
Gaby Sroczynski ◽  
Artemisa Gogollari ◽  
Annette Conrads-Frank ◽  
Lára R. Hallsson ◽  
Nora Pashayan ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Genetic Testing ◽  
Early Detection ◽  
Cost Effective ◽  
Endometrial Biopsy ◽  
Prevention Strategies ◽  
Life Years ◽  
Increased Risk ◽  
Risk Reducing ◽  
Early Detection And Prevention

Endometrial cancer is the most common female genital tract cancer in developed countries. We systematically reviewed the current health-economic evidence on early detection and prevention strategies for endometrial cancer based on a search in relevant databases (Medline/Embase/Cochrane Library/CRD/EconLit). Study characteristics and results including life-years gained (LYG), quality-adjusted life-years (QALY) gained, and incremental cost-effectiveness ratios (ICERs) were summarized in standardized evidence tables. Economic results were transformed into 2019 euros using standard conversion methods (GDP-PPP, CPI). Seven studies were included, evaluating (1) screening for endometrial cancer in women with different risk profiles, (2) risk-reducing interventions for women at increased or high risk for endometrial cancer, and (3) genetic testing for germline mutations followed by risk-reducing interventions for diagnosed mutation carriers. Compared to no screening, screening with transvaginal sonography (TVS), biomarker CA-125, and endometrial biopsy yielded an ICER of 43,600 EUR/LYG (95,800 EUR/QALY) in women with Lynch syndrome at high endometrial cancer risk. For women considering prophylactic surgery, surgery was more effective and less costly than screening. In obese women, prevention using Levonorgestrel as of age 30 for five years had an ICER of 72,000 EUR/LYG; the ICER for using oral contraceptives for five years as of age 50 was 450,000 EUR/LYG. Genetic testing for mutations in women at increased risk for carrying a mutation followed by risk-reducing surgery yielded ICERs below 40,000 EUR/QALY. Based on study results, preventive surgery in mutation carriers and genetic testing in women at increased risk for mutations are cost-effective. Except for high-risk women, screening using TVS and endometrial biopsy is not cost-effective and may lead to overtreatment. Model-based analyses indicate that future biomarker screening in women at increased risk for cancer may be cost-effective, dependent on high test accuracy and moderate test costs. Future research should reveal risk-adapted early detection and prevention strategies for endometrial cancer.

Effect of periodic endoscopy for gastric cancer on early detection and improving survival

2001 ◽  
Vol 120 (5) ◽  
pp. A606-A606
Author(s):  
Y MORII ◽  
T YOSHIDA ◽  
T MATSUMATA ◽  
T ARITA ◽  
K SHIMODA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Detection

1820: Complexed PSA for Early Detection of Prostate Cancer: A Multi Institutional Study

2004 ◽  
Vol 171 (4S) ◽  
pp. 481-481
Author(s):  
Ravery V. Vincent ◽  
Chautard D. Denis ◽  
Arnauld A. Villers ◽  
Laurent Boccon Gibbod
Keyword(s):  
Prostate Cancer ◽  
Early Detection
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