- Potential Anticoagulant Effect of Seaweed-Derived Biomaterials

2013 ◽  
pp. 470-479
Keyword(s):  
Anticoagulant Effect

“In vitro” Neutralization with Oxalate Ion of the Anticoagulant Effect of Heparin

1961 ◽  
Vol 05 (02) ◽  
pp. 314-318 ◽  
Author(s):  
W. O Cruz ◽  
L Meis ◽  
C. P Dietrich
Keyword(s):  
Calcium Oxalate ◽  
Aluminium Hydroxide ◽  
Barium Sulfate ◽  
Anticoagulant Effect ◽  
Normal Plasma ◽  
Oxalate Ion

SummaryHeparinized blood or plasma coagulates if, after addition of oxalate, recalcification follows. Of the decalcifying agents only oxalate ion has been suitable for demonstrating this phenomenon. Oxalate seem to accomplish two different roles connected with this effect: a fundamental one, i. e., to sensitize a heparinlipoprotein complex to the action of an anti-heparin factor found in normal plasma or serum and a secondary one, related to its capacity to adsorb this antiheparin factor. The latter is removable by centrifugation. This anti-heparin oxalate factor, which is able to counteract the action of heparin after previous addition of oxalate, was found in sequestrened, Dowex 50 resin plasma or in serum, but is not active in citrated plasma. This factor was removed from plasma by adsorption with barium sulfate, aluminium hydroxide or calcium oxalate and was eluted from these adsorbants after incubation with saline.

scholarly journals Enhancement of the anticoagulant effect of warfarin by gefitnib administration

2015 ◽  
Vol 26 ◽  
pp. vii138
Author(s):  
Yasuhiko Sakata ◽  
Yasuo Iwamoto ◽  
Keisuke Abe ◽  
Natsumi Okazaki ◽  
Junya Inata ◽  
...  
Keyword(s):  
Anticoagulant Effect

ATIII-independence of anticoagulant effect of human urinary soluble thrombomodulin

1999 ◽  
Vol 10 (8) ◽  
pp. 503-512 ◽  
Author(s):  
K. Imada ◽  
Y. Takahashi ◽  
Y. Hosaka ◽  
T. Adachi ◽  
H. Niina ◽  
...  
Keyword(s):  
Anticoagulant Effect ◽  
Soluble Thrombomodulin

Haloperidol and trifluperidol in psychiatry

1968 ◽  
Vol 6 (15) ◽  
pp. 58-59
Keyword(s):  
Anticoagulant Effect ◽  
Wild Animals ◽  
Experimental Animals ◽  
Amphetamine Toxicity ◽  
Conditioned Responses

Haloperidol (Serenace - Searle) and trifluperidol (Triperidol - Janssen) are butyrophenones and so are related chemically to pethidine. We have already discussed the pharmacology of the butyrophenones used in combination with analgesics and in anaesthesia.1 However, the group also has actions resembling those of the phenothiazines, such as chlorpromazine, in that they are anti-emetic, reduce or inhibit conditioned responses, tame wild animals and in larger doses induce catalepsy in experimental animals. They potentiate the effects of barbiturates and general anaesthetics, antagonise amphetamine toxicity and are reported to decrease the anticoagulant effect of phenindione.2 They are neither analgesic nor antanalgesic, and, unlike some phenothiazines, have little adrenolytic, hypothermic, hypotensive or soporific effect.

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