Reconciling Risks and Benefits of Hormone Replacement Therapy in a Single Outcome: The QALY Approach

2006 ◽  
pp. 255-262
Author(s):  
J Alt ◽  
Y Zöllner ◽  
J Ryan
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Risks And Benefits ◽  
Qaly Approach

scholarly journals Hormone Replacement Therapy After Gynaecological Malignancies: a Review Article

2021 ◽  
Vol 81 (05) ◽  
pp. 549-554
Author(s):  
Marina Sourouni ◽  
Ludwig Kiesel
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Current Knowledge ◽  
Hormone Replacement ◽  
Oncological Treatment ◽  
Oncological Safety ◽  
Risks And Benefits ◽  
Gynaecological Malignancy ◽  
Gynaecological Malignancies ◽  
Broad Overview

AbstractRapid advances in oncology have led to an increased survival rate in cancer patients, who live long enough to reach the natural age of menopause or experience the end of gonadal function as a side effect of oncological treatment. Survivors after gynaecological malignancies are a major challenge as these diseases are hormone-dependent and hormone replacement therapy (HRT) possibly increases the risk of recurrence. This article is based on a selective literature search for relevant studies and guidelines regarding HRT after gynaecological malignancies and provides a broad overview of current research. The data for assessing the oncological safety of HRT after gynaecological malignancy are insufficient overall. According to current knowledge, HRT is fundamentally contraindicated after breast and endometrial cancer. After ovarian cancer, HRT can be used after assessment of the risks and benefits, while there is usually no contraindication to HRT after vulvar, vaginal or cervical cancer.

THE LONG-TERM RISKS AND BENEFITS OF HORMONE REPLACEMENT THERAPY

1991 ◽  
Vol 16 (4) ◽  
pp. 231-245 ◽  
Author(s):  
T. C. Hillard ◽  
S. Whitcroft ◽  
M. C. Ellerington ◽  
M. I. Whitehead
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Risks And Benefits

scholarly journals Hormone Replacement Therapy: Risks and Benefits

2020 ◽  
Vol 7 ◽  
Author(s):  
Eriston Vieira Gomes
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Therapeutic Option ◽  
Hormone Replacement ◽  
Medical Practitioner ◽  
Clinical Approach ◽  
Vaginal Atrophy ◽  
Reproductive Senescence ◽  
Risks And Benefits

The climacteric is a physiological period of the female reproductive cycle characterized by a decrease in the levels of sex hormones, mainly estrogen. It consists of several phases, with amenorrhea as the initial clinical manifestation followed by long-term changes, such as vaginal atrophy. In this context, hormone replacement therapy (HRT) aims to improve the symptoms of female reproductive senescence, seeking to provide a comfortable physical and psychological condition during this period. However, as with any drug treatment, HRT has its risks and benefits, and it is up to the medical practitioner, in agreement with the patient, looking for the best therapeutic option, minimizing the risks and consequences resulting from this clinical approach.

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