Mechanical Properties of Human Skin: Biochemical Aspects

2001 ◽  
pp. 24-37
Keyword(s):  
Mechanical Properties ◽  
Human Skin

Capturing Age-Dependent Properties of Human Skin Using Magnetorheological Elastomers

2018 ◽  
Author(s):  
Kyle Weaver ◽  
Jeong-Hoi Koo ◽  
Tae-Heon Yang ◽  
Young-Min Kim
Keyword(s):  
Mechanical Properties ◽  
Human Skin ◽  
Skin Testing ◽  
Filler Particle ◽  
Variable Stiffness ◽  
Particle Volume ◽  
Magnetorheological Elastomers ◽  
Age Dependent ◽  
Skin Samples

Artificial and synthetic skins are widely used in the medical field; used in applications ranging from skin grafts to suture training pads. There is a growing need for artificial skins with tunable properties. However, current artificial skins do not take into account the variability of mechanical properties between individual humans as well as the age-dependent properties of human skin. Furthermore, there has been little development in artificial skins based on these properties. Thus, the primary purpose of this research is to develop variable stiffness artificial skin samples using magnetorheological elastomers (MREs) whose properties that can be controlled using external magnetic fields. In this study, multiple MRE skin samples were fabricated with varying filler particle volume contents. Using a precision dynamic mechanical analyzer, a series of indenting experiments were performed on the samples to characterize their mechanical properties. The samples were tested using a spherical indenter that indented a total depth of 1 mm with a speed of 0.01 mm/s and unloaded at the same rate. The results show that the modulus or stiffness increases significantly as the iron percent (w/w) in the sample increases. Additionally, the stiffness of the sample increases proportional to the intensity of the applied external magnetic field. To assess the MRE samples’ variability of properties, the testing results were compared with in vivo human skin testing data. The results show the MRE samples are feasible to represent the age-dependent stiffness demonstrated in in vivo human skin testing. The MRE materials studied will be further studied as a variable-stiffness skin model in medical devices, such as radial pulse simulators.

scholarly journals Reactivating the extracellular matrix synthesis of sulfated glycosaminoglycans and proteoglycans to improve the human skin aspect and its mechanical properties

2016 ◽  
Vol Volume 9 ◽  
pp. 461-472 ◽  
Author(s):  
Hanane Chajra ◽  
Daniel Auriol ◽  
Francine Joly ◽  
Aurélie Pagnon ◽  
Magda Rodrigues ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Extracellular Matrix ◽  
Human Skin ◽  
Matrix Synthesis

Effects of treatment with prednisolone and PUVA on the mechanical properties of human skin in vivo

1981 ◽  
pp. 31-43
Author(s):  
C. W. Gunner ◽  
E. W. Williams ◽  
M. Greaves ◽  
W. C. Hutton ◽  
T. E. Burlin
Keyword(s):  
Mechanical Properties ◽  
Human Skin

scholarly journals Fabrication of Second Skin from Keratin and Melanin

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2568
Author(s):  
Chen Nowogrodski ◽  
Ido Simon ◽  
Shlomo Magdassi ◽  
Oded Shoseyov
Keyword(s):  
Mechanical Properties ◽  
High Resolution ◽  
Human Skin ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Light Transmittance ◽  
Fabrication Method ◽  
Melanin Content ◽  
Toxic Materials ◽  
High Resolution Images

Second skin is a topically applied, skin-conforming material that mimics human skin properties and bears potential cosmetic and e-skin applications. To successfully integrate with natural skin, characteristics such as color and skin features must be matched. In this work, we prepared bio-based skin-like films from cross-linked keratin/melanin films (KMFs), using a simple fabrication method and non-toxic materials. The films retained their stability in aqueous solutions, showed skin-like mechanical properties, and were homogenous and handleable, with non-granular surfaces and a notable cross-linked structure as determined by attenuated total reflection (ATR). In addition, the combination of keratin and melanin allowed for adjustable tones similar to those of natural human skin. Furthermore, KMFs showed light transmittance and UV-blocking (up to 99%) as a function of melanin content. Finally, keratin/melanin ink (KMI) was used to inkjet-print high-resolution images with natural skin pigmented features. The KMFs and KMI may offer advanced solutions as e-skin or cosmetics platforms.

New extensometer to measure in vivo uniaxial mechanical properties of human skin

2008 ◽  
Vol 41 (5) ◽  
pp. 931-936 ◽  
Author(s):  
K.H. Lim ◽  
C.M. Chew ◽  
P.C.Y. Chen ◽  
S. Jeyapalina ◽  
H.N. Ho ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Human Skin
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