Aging of Immune and Hormonal Responses

2001 ◽  
pp. 237-263
Author(s):  
Shoji Shinkai
Keyword(s):  
Hormonal Responses

Counterregulation of insulin-induced hypoglycaemia in primary hypothyroidism

1986 ◽  
Vol 111 (4) ◽  
pp. 516-521
Author(s):  
Nina Clausen ◽  
Per-Eric Lins ◽  
Ulf Adamson ◽  
Bertil Hamberger ◽  
Suad Efendić
Keyword(s):  
Growth Hormone ◽  
Insulin Infusion ◽  
Primary Hypothyroidism ◽  
Constant Rate Infusion ◽  
Counterregulatory Hormones ◽  
Insulin Metabolism ◽  
Hormonal Responses ◽  
Glucose Levels ◽  
Constant Rate ◽  
Rate Infusion

Abstract. Hypothyroidism has been alleged to modulate insulin action and influence the secretion of growth hormone and catecholamines. We recently investigated the influence of hypothyroidism on glucose counterregulatory capacity and the hormonal responses to insulin-induced hypoglycaemia in 6 patients with primary hypothyroidism (age 32–52 years, TSH-values 66–200 mU/l). Hypoglycaemia was induced in the hypothyroid state and again when the subjects were euthyroid. After an overnight fast a constant rate infusion of insulin (2.4 U/h) was given for 4 h. Glucose was measured every 15 min and insulin, C-peptide, glucagon, epinephrine, norepinephrine, growth hormone and cortisol every 30 min for 5 h. During insulin infusion somewhat higher concentrations of the hormone were obtained in the hypothyroid state and simultaneously glucose levels were 0.5 mmol/l lower. As expected, basal norepinephrine levels were higher in hypothyroidism. However, no increase in circulating norepinephrine during hypoglycaemia was registered in the two experiments. The responses of counterregulatory hormones showed an enhanced response of cortisol, similar responses of growth hormone and epinephrine while the glucagon response was paradoxically impaired. Our findings suggest that hypothyroidism alters insulin metabolism, and that the glucagon response to hypoglycaemia is impaired in this condition.

A test of the hypothesis that the rate of fall in glucose concentration triggers counterregulatory hormonal responses in man

Diabetes ◽  
1977 ◽  
Vol 26 (5) ◽  
pp. 445-452 ◽  
Author(s):  
R. A. DeFronzo ◽  
R. Andres ◽  
T. A. Bedsoe ◽  
G. Boden ◽  
G. A. Faloona ◽  
...  
Keyword(s):  
Glucose Concentration ◽  
Hormonal Responses

Importance of insulin in subjective, cognitive, and hormonal responses to hypoglycemia in patients with IDDM

Diabetes ◽  
1991 ◽  
Vol 40 (8) ◽  
pp. 1057-1062 ◽  
Author(s):  
D. Kerr ◽  
M. Reza ◽  
N. Smith ◽  
B. A. Leatherdale
Keyword(s):  
Hormonal Responses

scholarly journals The Arabidopsis cax1 Mutant Exhibits Impaired Ion Homeostasis, Development, and Hormonal Responses and Reveals Interplay among Vacuolar Transporters

2003 ◽  
Vol 15 (2) ◽  
pp. 347-364 ◽  
Author(s):  
Ning-Hui Cheng ◽  
Jon K. Pittman ◽  
Bronwyn J. Barkla ◽  
Toshiro Shigaki ◽  
Kendal D. Hirschi
Keyword(s):  
Ion Homeostasis ◽  
Hormonal Responses

The Role of Opioid Peptides in the Hormonal Responses to Acute Exercise in Man

1984 ◽  
Vol 67 (5) ◽  
pp. 483-491 ◽  
Author(s):  
A. Grossman ◽  
P. Bouloux ◽  
P. Price ◽  
P. L. Drury ◽  
K. S. L. Lam ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Plasma Renin Activity ◽  
Acute Exercise ◽  
Plasma Renin ◽  
Endogenous Opioids ◽  
Renin Activity ◽  
High Dose ◽  
Hormonal Responses ◽  
Physiological Variables ◽  
Severe Exercise

1. Opioid involvement in the physiological and hormonal responses to acute exercise was investigated in six normal male subjects. Each was exercised to 40% (mild exercise) and 80% (severe exercise) of his previously determined maximal oxygen consumption on two occasions, with and without an infusion of high-dose naloxone. The exercise task was a bicycle ergometer; mild and severe exercise were performed for 20 min each, followed by a recovery period. 2. Exercise produced the expected increases in heart rate, blood pressure, ventilation, tidal volume, respiratory rate, oxygen consumption and carbon dioxide production. After severe exercise, naloxone infusion increased ventilation from 94.8 ± 4.9 litres/min to 105.7 ± 5.0 litres/min (P<0.05), but had no effect on any of the other physiological variables. 3. Exercise-induced changes in several hormones and metabolites were noted, including elevations in circulating lactate, growth hormone (GH), prolactin, cortisol, luteinizing hormone (LH), follicle stimulating hormone (FSH), adrenaline, noradrenaline, plasma renin activity (PRA) and aldosterone. There was no change in plasma met-enkephalin. Naloxone infusion produced the expected increases in LH and cortisol, but also significantly enhanced the elevations in prolactin, adrenaline, noradrenaline, plasma renin activity and aldosterone (P<0.05). 4. Psychological questionnaires revealed minor mood changes after exercise, but no evidence was found for the suggested ‘high’ or euphoria of exercise. Effort was perceived as greater during the naloxone infusion than the saline infusion in every subject. 5. We conclude that endogenous opioids may be important in the control of ventilation and the perception of effort at high levels of power output, and may modulate the responses of circulating catecholamines and the renin-aldosterone system to acute physical stress.

Hormonal Responses to Resistance Exercise in Long-Term Trained and Untrained Middle-Aged Men

2008 ◽  
Vol 22 (5) ◽  
pp. 1617-1624 ◽  
Author(s):  
Eduardo Lusa Cadore ◽  
Francisco Luiz Rodrigues Lhullier ◽  
Michel Arias Brentano ◽  
Eduardo Marczwski da Silva ◽  
Melissa Bueno Ambrosini ◽  
...  
Keyword(s):  
Resistance Exercise ◽  
Middle Aged ◽  
Hormonal Responses

Hormonal responses to trauma

1992 ◽  
Vol 20 (2) ◽  
pp. 216-226 ◽  
Author(s):  
PAUL D. WOOLF
Keyword(s):  
Hormonal Responses

The effect of the CCKA receptor antagonist loxiglumide on hormonal responses, gastric emptying and appetite in humans

2000 ◽  
Vol 94 (1-3) ◽  
pp. 71
Author(s):  
Linda M. Morgan ◽  
Samantha J. Long ◽  
Andrew Sutton ◽  
Anastasia Giouvanoudi ◽  
Behain Amaee ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Receptor Antagonist ◽  
Hormonal Responses
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