Selection of Local Anesthetic and Adjuvants

2006 ◽  
pp. 41-46
2020 ◽  
Author(s):  
Britlyn D. Orgill ◽  
Douglas L. Helm

Advances in anesthesia have expanded the field of plastic surgery by allowing more procedures to be done, while also increasing the safety of the patient. Anesthesia is a spectrum ranging from local anesthetic injected by the surgeon, to regional and neuraxial blocks or general anesthesia with an anesthesia team. Anesthesiologists work with the surgeon to assess a patient’s preoperative risk and make joint decisions to determine if additional medical optimization is needed prior to surgery. New peripheral blocks allow alternatives to general anesthesia or serve as adjuncts to improve post-operative pain. Selection of drugs used to induce and maintain anesthesia are changing with the advent of Enhanced Recovery After Surgery Protocols and emphasis on decreasing opioids. Teamwork and excellent communication are imperative to navigate anesthetic and surgical emergencies.  This review contains 3 figures, 4 tables, and 29 references. Keywords: sedation, general anesthesia, regional anesthesia, peripheral nerve blocks, local anesthetic toxicity syndrome, ASA physical status, preoperative fasting guidelines, opioids, multi-modal analgesia, ERAS, crisis checklists


2018 ◽  
pp. 21-25
Author(s):  
A. M. Karamyshev ◽  
G. V. Iliukevich

Objective : to carry out comparative assessment of effectiveness of different techniques of combined anesthesia in surgical correction of congenital disorders of the urinogenital system by means of the analysis of changes of integrative hemodynamic parameters. Material and methods . 116 patients were divided into 3 clinical groups depending on the type of ananesthetic aid. In the first group (40 patients), surgeries were performed under multicomponent balanced inhalation anesthesia, in the second group (42 patients) - under common inhalation anesthesia in combination with caudal blockade with solution of local anesthetic and patients of the third group (34 patients) were operated under common inhalation anesthesia with caudal blockade with solution of local anesthetic and an adjuvant.The calculation of the integrative hemodynamic parameters at 8 surgery stages (K-1 and K-2) was made for different techniques of anesthesia. Results. We have revealed statistically significant differences in the studied parameters of hemodynamics at certain stages of the perioperational period corresponding to the beginning of the surgery and its most traumatic stage in both the clinical groups, which reasoned in favor of more efficient blockade of painful sensitivity in the application of caudal analgesia. The technique of combined anesthesia with application of the combination of local anesthetic solutions and an adjuvant during surgical correction of congenital disorder of the urinogenital system in children has appeared to be the most efficient and adequate, which has been indicated by the studied hemodynamic parameters.


e-GIGI ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Muhammad Ikhsan ◽  
Ni Wayan Mariati ◽  
Christy Mintjelungan

Abstract: Local anesthetic agent is one of the materials most commonly used in dentistry. Local anesthetic agent used for relieving pain arising from dental procedures. Local anesthetic agent is divided into two groups, namely esters and amides. This study provides information on the availability of local anesthetic agent in Manado. The purpose of this study to describe the use of local anesthesia by a dentist in the city of Manado. This type of research is a descriptive study and sampling was performed with a total sampling method. Retrieval of data by means of questionnaires by a dentist who practiced in the city of Manado. The number of samples in this study were 31 dentists. The results found that 22 dentists (70.96%) using the amide groups lidocaine HCl 2% and 2 dentists (6,45%) procaine and benzocaine is an ester group. The effectiveness of the local anesthetic agent is a major reason in the selection of a local anesthetic agent that is 90.32% or 28 dentists. Keywords: local anesthetic agents.     Abstrak: Bahan anestesi lokal merupakan salah satu bahan yang paling sering digunakan dalam kedokteran gigi. Bahan anestesi lokal digunakan untuk menghilangkan rasa sakit yang timbul akibat prosedur kedokteran gigi. Bahan anestesi lokal terbagi dua golongan yaitu ester dan amida. Penelitian ini memberikan informasi ketersediaan bahan anestesi lokal di Manado. Tujuan penelitian ini untuk mengetahui gambaran penggunaan bahan anestesi lokal oleh dokter gigi di kota Manado. Jenis penelitian yang digunakan yaitu penelitian deskriptif dan pengambilan sampel dilakukan dengan metode total sampling. Pengambilan data dengan cara pengisian kuesioner oleh dokter gigi yang berpraktik di kota Manado. Jumlah sampel dalam penelitian ini sebanyak 31 dokter gigi. Hasil penelitian mendapati bahwa 22 dokter gigi (70,96%) menggunakan golongan amida yaitu lidokain HCl 2% dan 2 dokter gigi (6,45%) golongan ester yaitu prokain dan benzokain. Keefektifan bahan anestesi lokal merupakan alasan utama dalam pemilihan bahan anestesi lokal yaitu 90,32% atau 28 orang dokter gigi. Kata kunci: bahan anestesi lokal.


2019 ◽  
Vol 42 ◽  
Author(s):  
Gian Domenico Iannetti ◽  
Giorgio Vallortigara

Abstract Some of the foundations of Heyes’ radical reasoning seem to be based on a fractional selection of available evidence. Using an ethological perspective, we argue against Heyes’ rapid dismissal of innate cognitive instincts. Heyes’ use of fMRI studies of literacy to claim that culture assembles pieces of mental technology seems an example of incorrect reverse inferences and overlap theories pervasive in cognitive neuroscience.


1975 ◽  
Vol 26 ◽  
pp. 395-407
Author(s):  
S. Henriksen

The first question to be answered, in seeking coordinate systems for geodynamics, is: what is geodynamics? The answer is, of course, that geodynamics is that part of geophysics which is concerned with movements of the Earth, as opposed to geostatics which is the physics of the stationary Earth. But as far as we know, there is no stationary Earth – epur sic monere. So geodynamics is actually coextensive with geophysics, and coordinate systems suitable for the one should be suitable for the other. At the present time, there are not many coordinate systems, if any, that can be identified with a static Earth. Certainly the only coordinate of aeronomic (atmospheric) interest is the height, and this is usually either as geodynamic height or as pressure. In oceanology, the most important coordinate is depth, and this, like heights in the atmosphere, is expressed as metric depth from mean sea level, as geodynamic depth, or as pressure. Only for the earth do we find “static” systems in use, ana even here there is real question as to whether the systems are dynamic or static. So it would seem that our answer to the question, of what kind, of coordinate systems are we seeking, must be that we are looking for the same systems as are used in geophysics, and these systems are dynamic in nature already – that is, their definition involvestime.


1978 ◽  
Vol 48 ◽  
pp. 515-521
Author(s):  
W. Nicholson

SummaryA routine has been developed for the processing of the 5820 plates of the survey. The plates are measured on the automatic measuring machine, GALAXY, and the measures are subsequently processed by computer, to edit and then refer them to the SAO catalogue. A start has been made on measuring the plates, but the final selection of stars to be made is still a matter for discussion.


Author(s):  
P.J. Killingworth ◽  
M. Warren

Ultimate resolution in the scanning electron microscope is determined not only by the diameter of the incident electron beam, but by interaction of that beam with the specimen material. Generally, while minimum beam diameter diminishes with increasing voltage, due to the reduced effect of aberration component and magnetic interference, the excited volume within the sample increases with electron energy. Thus, for any given material and imaging signal, there is an optimum volt age to achieve best resolution.In the case of organic materials, which are in general of low density and electric ally non-conducting; and may in addition be susceptible to radiation and heat damage, the selection of correct operating parameters is extremely critical and is achiev ed by interative adjustment.


Author(s):  
P. M. Lowrie ◽  
W. S. Tyler

The importance of examining stained 1 to 2μ plastic sections by light microscopy has long been recognized, both for increased definition of many histologic features and for selection of specimen samples to be used in ultrastructural studies. Selection of specimens with specific orien ation relative to anatomical structures becomes of critical importance in ultrastructural investigations of organs such as the lung. The uantity of blocks necessary to locate special areas of interest by random sampling is large, however, and the method is lacking in precision. Several methods have been described for selection of specific areas for electron microscopy using light microscopic evaluation of paraffin, epoxy-infiltrated, or epoxy-embedded large blocks from which thick sections were cut. Selected areas from these thick sections were subsequently removed and re-embedded or attached to blank precasted blocks and resectioned for transmission electron microscopy (TEM).


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