The Use of PET to Evaluate Neural Plasticity and Repair in Rodent Brain

Abstract. In Germany, 7.5 Million individuals between 18 and 64 years are considered to be functionally illiterate (Grotlüschen & Riekmann, 2012). Functional illiterates have only rudimentary literacy skills despite attending school for several years. Although they can use written language to a very limited extent, only few functional illiterates attend literacy courses for adults. In addition, most adult literacy courses primarily aim at promoting basic reading and writing skills. Offers specific to workplace literacy are scarce. This review gives an overview of the definition of functional illiteracy. Afterwards, a specific literacy program (AlphaPlus) and its effectiveness will be presented. The reviewed studies indicate that learning to read in adulthood is associated with structural and functional brain changes.

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“Neural Plasticity in Rehabilitation and Psychotherapy – New Perspectives and Findings”

Zeitschrift für Psychologie ◽

10.1027/2151-2604/a000202 ◽

2015 ◽

Vol 223 (1) ◽

pp. 66-66

Author(s):

Wolfgang H. R. Miltner ◽

Otto W. Witte

Keyword(s):

Neural Plasticity

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Adaptive and Maladaptive Neural Plasticity Due to Facial Nerve Palsy

Zeitschrift für Psychologie ◽

10.1027/2151-2604/a000244 ◽

2016 ◽

Vol 224 (2) ◽

pp. 102-111 ◽

Cited By ~ 1

Author(s):

Carsten M. Klingner ◽

Stefan Brodoehl ◽

Gerd F. Volk ◽

Orlando Guntinas-Lichius ◽

Otto W. Witte

Keyword(s):

Facial Nerve ◽

Neural Plasticity ◽

Cortical Plasticity ◽

Brain Plasticity ◽

Motor Nerve ◽

Predictive Coding ◽

Theoretical Framework ◽

Cortical Reorganization ◽

Nerve Lesion ◽

Peripheral Facial Palsy

Abstract. This paper reviews adaptive and maladaptive mechanisms of cortical plasticity in patients suffering from peripheral facial palsy. As the peripheral facial nerve is a pure motor nerve, a facial nerve lesion is causing an exclusive deefferentation without deafferentation. We focus on the question of how the investigation of pure deefferentation adds to our current understanding of brain plasticity which derives from studies on learning and studies on brain lesions. The importance of efference and afference as drivers for cortical plasticity is discussed in addition to the crossmodal influence of different competitive sensory inputs. We make the attempt to integrate the experimental findings of the effects of pure deefferentation within the theoretical framework of cortical responses and predictive coding. We show that the available experimental data can be explained within this theoretical framework which also clarifies the necessity for maladaptive plasticity. Finally, we propose rehabilitation approaches for directing cortical reorganization in the appropriate direction and highlight some challenging questions that are yet unexplored in the field.

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