Breast cancer in the elderly

2013 ◽  
pp. 505-514
Author(s):  
R Leonard ◽  
G Thomas
Keyword(s):  
Breast Cancer ◽  
The Elderly

Management of early stage breast cancer in the elderly

Aging Health ◽  
2006 ◽  
Vol 2 (2) ◽  
pp. 245-251
Author(s):  
Joanne E Mortimer ◽  
Sarah L Blair
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
The Elderly ◽  
Early Stage Breast Cancer

Palliative Care in the Elderly Breast Cancer Patient

2009 ◽  
Vol 21 (2) ◽  
pp. 131-139 ◽  
Author(s):  
B.J.A. Laird ◽  
M.T. Fallon
Keyword(s):  
Breast Cancer ◽  
Palliative Care ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
The Elderly

Breast Cancer in the Elderly

2007 ◽  
Vol 25 (14) ◽  
pp. 1882-1890 ◽  
Author(s):  
Diana Crivellari ◽  
Matti Aapro ◽  
Robert Leonard ◽  
Gunter von Minckwitz ◽  
Etienne Brain ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trials ◽  
Life Expectancy ◽  
Cancer Patients ◽  
Disease Free Survival ◽  
Cost Benefit ◽  
The Elderly ◽  
Breast Cancer Patients ◽  
Younger Women ◽  
Based Medicine

Screening and adjuvant postoperative therapies have increased survival among women with breast cancer. These tools are seldom applied in elderly patients, although the usually reported incidence of breast cancer is close to 50% in women 65 years or older, reaching 47% after 70 years in the updated Surveillance, Epidemiology, and End Results (SEER) database. Elderly breast cancer patients, even if in good medical health, were frequently excluded from adjuvant clinical trials. Women age 70 years who are fit actually have a median life expectancy of 15.5 years, ie, half of them will live much longer and will remain exposed for enough time to the potentially preventable risks of a relapse and specific death. In the last few years, a new concern about this issue has developed. Treatment now faces two major end points, as in younger women: to improve disease-free survival in the early stages, and to palliate symptoms in advanced disease. However, in both settings, the absolute benefit of treatment is critical because protecting quality of life and all its related aspects (especially functional status and independence), is crucial in older persons who have more limited life expectancy. Furthermore, the new hormonal compounds (aromatase inhibitors) and chemotherapeutic drugs (capecitabine, liposomal doxorubicin), are potentially less toxic than and equally as effective as older more established therapies. These new treatments bring new challenges including higher cost, and defining their benefit in elderly breast cancer must include an analysis of the cost/benefit ratio. These issues emphasize the urgent need to develop and support clinical trials for this older population of breast cancer patients both in the adjuvant and metastatic settings, a move that will take us from a prejudiced, age-based medicine to an evidence-based medicine.

Dose Dense and Concurrent Trastuzumab for Early Breast Cancer in the Elderly

2011 ◽  
Vol 23 (7) ◽  
pp. 494-495
Author(s):  
U.Y. Cheema ◽  
S. Kalapurakal ◽  
P. White ◽  
A.U. Khan
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
The Elderly ◽  
Dose Dense

Omission of Adjuvant Radiotherapy in the Elderly Breast Cancer Patient: Missed Opportunity?

2018 ◽  
Vol 18 (5) ◽  
pp. 418-431 ◽  
Author(s):  
Alex C. Herskovic ◽  
Xian Wu ◽  
Paul J. Christos ◽  
Himanshu Nagar
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Adjuvant Radiotherapy ◽  
The Elderly ◽  
Missed Opportunity

scholarly journals Quality of Life and Depressive Signs and Symptoms of the Elderly Women with Breast Cancer

10.3823/2055 ◽  
2016 ◽  
Author(s):  
Nathacha Adriela Lima de Carvalho ◽  
Maria do Livramento Fortes Figueiredo ◽  
Chrystiany Plácido de Brito Vieira ◽  
Jaqueline Carvalho e Silva Sales ◽  
Maria Helena Barros Araújo Luz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Elderly Women ◽  
Signs And Symptoms ◽  
The Elderly

Individualizing Local-Regional Therapy of Breast Cancer in the Elderly

2018 ◽  
Vol 10 (2) ◽  
pp. 98-109
Author(s):  
Apoorve Nayyar ◽  
Trevor A. Jolly ◽  
Ellen T. Jones ◽  
Kandace P. McGuire ◽  
Hyman B. Muss ◽  
...  
Keyword(s):  
Breast Cancer ◽  
The Elderly ◽  
Regional Therapy
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