Chronic Exercise and Immunity

2013 ◽  
pp. 605-614
Author(s):  
Paul Coen ◽  
Michael Flynn
Keyword(s):  
Chronic Exercise

Effect of Chronic Exercise on Trait Anxiety in College Students

2011 ◽  
Author(s):  
Michael T. Rothman ◽  
Jill Welkley ◽  
Rebecca L. Brock ◽  
Alexia D. Rothman ◽  
Stephen Nowicki
Keyword(s):  
College Students ◽  
Trait Anxiety ◽  
Chronic Exercise

scholarly journals The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans

FEBS Journal ◽  
2013 ◽  
Vol 281 (3) ◽  
pp. 739-749 ◽  
Author(s):  
Frode Norheim ◽  
Torgrim Mikal Langleite ◽  
Marit Hjorth ◽  
Torgeir Holen ◽  
Anders Kielland ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Chronic Exercise ◽  
Subcutaneous Adipose

Reduced triglyceride secretion: a metabolic consequence of chronic exercise.

1978 ◽  
Vol 234 (3) ◽  
pp. E221 ◽  
Author(s):  
C Simonelli ◽  
R P Eaton
Keyword(s):  
Exercise Training ◽  
Genetic Model ◽  
Secretion Rate ◽  
Lipid Lowering ◽  
Zucker Rat ◽  
Chronic Exercise ◽  
Similar Reduction ◽  
Triglyceride Secretion ◽  
Obese Zucker Rat

Chronic exercise training is recognized to reduce plasma lipid levels in man and animals, but the mechanism(s) mediating this phenomenon have not been defined. In the present study, we examined triglyceride (TG) production and disposal in vivo in a genetic model of human type IV hyperlipemia, the obese Zucker rat. Utilizing the normolipemic thin littermate as the control, we investigated endogenous production of TG utilizing the Triton methodology and peripheral disposal of an exogenous lipid emulsion utilizing Intralipid injection. In the sedentary state, the hyperlipemic obese Zucker rat demonstrated a threefold elevation in triglyceride secretion rate relative to the normolipemic thin littermate. After a 3-wk period of exercise training, a reduction of basal plasma TG concentration of 42% was associated with a 51% reduction in TG secretion rate, a change adequate to account for the hypolipemic response. Moreover, chronic exercise training also improved the ability to dispose of an Intralipid load. A similar reduction in TG production with reduced TG removal was observed in the thin normolipemic rats, a result that suggests that the lipid lowering response to exercise training may be predominantly mediated by reduced secretion of TG. The possible relationship between reduced TG secretion and alterations in the bihormonal axis of insulin and glucagon are discussed.

Role of irisin in effects of chronic exercise on muscle and bone in ovariectomized mice

2021 ◽  
Author(s):  
Naoyuki Kawao ◽  
Shunki Iemura ◽  
Miku Kawaguchi ◽  
Yuya Mizukami ◽  
Yoshimasa Takafuji ◽  
...  
Keyword(s):  
Chronic Exercise ◽  
Ovariectomized Mice

Long-Term Exercise Training Selectively Alters Serum Cytokines Involved in Fever

2009 ◽  
Vol 10 (4) ◽  
pp. 374-380 ◽  
Author(s):  
Pamela Johnson Rowsey ◽  
Bonnie L. Metzger ◽  
John Carlson ◽  
Christopher J. Gordon
Keyword(s):  
Exercise Training ◽  
Core Temperature ◽  
Binding Capacity ◽  
Serum Zinc ◽  
Female Rats ◽  
Chronic Exercise ◽  
Serum Cytokines ◽  
Tnf Α ◽  
Running Wheels

Long-term exercise training selectively alters serum cytokines involved in fever. Chronic exercise training has a number of effects on the immune system that may mimic the physiological response to fever. Female rats that voluntarily exercise on running wheels develop an elevated daytime core temperature after several weeks of training. It remains to be seen whether the elevation in daytime temperature involves inflammatory patterns characteristic of an infectious fever. We assessed whether chronic exercise training in the rat would alter levels of cytokines involved in fever. Female Sprague Dawley rats at 45 days of age weighing 90—110 g were divided into two groups (exercise and sedentary) and housed at an ambient temperature of 22°C. Interleukin-1 beta (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor alpha (TNF-α), iron, and zinc levels were analyzed. Rats underwent 8 weeks of exercise on running wheels. Exercise led to altered levels of some key cytokines that are involved in fever. Exercise animals had significantly higher IL-1β levels and lower IL-10 levels compared to sedentary animals. Although IL-6 levels were slightly lower in the exercise animals, these levels were not significantly affected by training. TNF-α activity was similar in the two groups. Training also led to a slight increase in serum zinc and decrease in serum unsaturated iron binding capacity (UIBC). The data suggest that chronic exercise training evokes immune responses that mimic some, but not all, aspects of fever. This may explain why exercise leads to elevated daytime core temperature.

scholarly journals Chronic Exercise Increases Plasma Brain-Derived Neurotrophic Factor Levels, Pancreatic Islet Size, and Insulin Tolerance in a TrkB-Dependent Manner

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e115177 ◽  
Author(s):  
Alberto Jiménez-Maldonado ◽  
Elena Roces de Álvarez-Buylla ◽  
Sergio Montero ◽  
Valery Melnikov ◽  
Elena Castro-Rodríguez ◽  
...  
Keyword(s):  
Pancreatic Islet ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Dependent Manner ◽  
Chronic Exercise ◽  
Insulin Tolerance ◽  
Islet Size
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