Lifestyle Strategies for Risk Factor Reduction, Prevention and Treatment of Coronary Artery Disease

2013 ◽  
pp. 19-34
Author(s):  
James Rippe ◽  
Theodore Angelopoulos
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Risk Factor Reduction ◽  
Prevention And Treatment ◽  
Artery Disease

Efficacy of Lipid Apheresis: Definitions and Influencing Factors

1995 ◽  
Vol 18 (4) ◽  
pp. 210-215 ◽  
Author(s):  
T. Bosch ◽  
D. Seidel ◽  
H. J. Gurland
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Clinical Efficacy ◽  
Plasma Volume ◽  
Lipid Apheresis ◽  
Term Efficacy ◽  
Risk Factor Reduction ◽  
Artery Disease

The comparison of efficiency of currently available lipid apheresis systems has been hampered by different definitions of efficacy and poorly controlled apheresis conditions. This paper suggests definitions of efficacy and standardization of its determinants. The acute efficacy of risk factor reduction reflects the relative decrease of pathogen by a single treatment session compared to preapheresis levels. Standardization of treated plasma volume in relation to the patients plasma volume and correction of changes in plasma volume during the procedure are mandatory. Its determination is most useful in the technical evaluation of new systems. The long-term efficacy of risk factor reduction as compared to baseline is determined by mean interapheresis levels of e.g. LDL-C in the pseudo-steady-state after about 3 months of regular treatment. It is the major criterion for potential regression of coronary artery disease and absolute average plasma levels of 120 ≤ mg/dl LDL-C should be attained. It is influenced by the acute efficacy of the system, apheresis frequency and rebound kinetics. The clinical efficacy is defined by apheresis induced reduction of coronary morbidity and mortality. It is influenced by long-term risk factor reduction, the selectivity of the system as well as the control of non-lipid risk factors. Apheresis related effects on coronary artery disease comprise functional improvements of hemorheology and vasomotion as well as morphological benefits like regression of luminal narrowing and plaque stabilization. In conclusion, the acute efficacy of apheresis systems should be determined under strictly controlled conditions; however, as apheresis independent factors influence long-term efficacy and, even more so, clinical efficacy of the treatment, differences between the available systems are blurred so that factors like costs and ease of handling may eventually significantly influence the choice of procedure.

scholarly journals Risk factor reduction in progression of angiographic coronary artery disease

2012 ◽  
Vol 3 ◽  
pp. 444-448 ◽  
Author(s):  
Hoang M. Lai ◽  
Wilbert S. Aronow ◽  
Anthony D. Mercando ◽  
Phoenix Kalen ◽  
Harit V. Desai ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Risk Factor Reduction ◽  
Artery Disease

scholarly journals Features of metabolic disorders in the patients with diseases associated with atherosclerosis, on the background of functional bile outflow abnormalities

2014 ◽  
Vol 21 (1) ◽  
pp. 45-48 ◽  
Author(s):  
I. A. Gorbacheva ◽  
Yu. A. Sycheva ◽  
P. S. Shabak-Spassky ◽  
L. A. Nikolaeva ◽  
L. G. Vladimirova
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Metabolic Disorders ◽  
Chronic Coronary Artery Disease ◽  
Cardiovascular Pathology ◽  
Atherosclerosis Progression ◽  
Prevention And Treatment ◽  
Integrated Approaches ◽  
Artery Disease

The paper presents the results of evaluation of the pathogenetic relationship between atherosclerosis and functional abnormalities of the bile outflow. The main group included 54 patients with cardiovascular pathology and biliary dyskinesia. The group of comparison consisted of 20 patients with chronic coronary artery disease. The results suggest that the functional bile outflow abnormality is a risk factor of atherosclerosis progression leading to hypercholesterolemia and dyslipidemia, and should be considered in the development of integrated approaches to prevention and treatment of the diseases caused by atherosclerosis.

scholarly journals 170 Psoriasis and coronary artery disease share a genetic risk factor through IFIH1

2021 ◽  
Vol 141 (5) ◽  
pp. S30
Author(s):  
M.T. Patrick ◽  
S. Sreeskandarajan ◽  
Q. Li ◽  
N. Mehta ◽  
J.E. Gudjonsson ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Genetic Risk ◽  
Genetic Risk Factor ◽  
Artery Disease
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