Tanapox Virus

2016 ◽  
pp. 1067-1074
Keyword(s):  
Tanapox Virus

Studies on tanapox virus

Virology ◽  
1989 ◽  
Vol 172 (1) ◽  
pp. 116-124 ◽  
Author(s):  
Janice C. Knight ◽  
FrancisJ. Novembre ◽  
Denise R. Brown ◽  
Cynthia S. Goldsmith ◽  
Joseph J. Esposito
Keyword(s):  
Tanapox Virus

Multiple anti-cytokine activities secreted from tanapox virus-infected cells

1994 ◽  
Vol 17 (5) ◽  
pp. 347-353 ◽  
Author(s):  
Karim Essani ◽  
Sridhar Chalasani ◽  
Robert Eversole ◽  
Leonard Beuving ◽  
Lee Birmingham
Keyword(s):  
Tanapox Virus ◽  
Infected Cells

Abstract 2716: Development of tanapox virus for oncolytic therapy

2012 ◽  
Author(s):  
Krystal N. Seibert ◽  
Karim Essani ◽  
Bruce E. Bejcek
Keyword(s):  
Oncolytic Therapy ◽  
Tanapox Virus

scholarly journals The Addition of Tumor Necrosis Factor plus Beta Interferon Induces a Novel Synergistic Antiviral State against Poxviruses in Primary Human Fibroblasts

2008 ◽  
Vol 83 (2) ◽  
pp. 498-511 ◽  
Author(s):  
Eric Bartee ◽  
Mohamed R. Mohamed ◽  
M. Cecilia Lopez ◽  
Henry V. Baker ◽  
Grant McFadden
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Human Fibroblasts ◽  
Global Gene Expression ◽  
Myxoma Virus ◽  
Antiviral State ◽  
Tanapox Virus ◽  
Novel Host ◽  
The Individual ◽  
Necrosis Factor

ABSTRACT Tumor necrosis factor (TNF) and members of the interferon (IFN) family have been shown to independently inhibit the replication of a variety of viruses. In addition, previous reports have shown that treatment with various combinations of these antiviral cytokines induces a synergistic antiviral state that can be significantly more potent than addition of any of these cytokines alone. The mechanism of this cytokine synergy and its effects on global gene expression, however, are not well characterized. Here, we use DNA microarray analysis to demonstrate that treatment of uninfected primary human fibroblasts with TNF plus IFN-β induces a distinct synergistic state characterized by significant perturbations of several hundred genes which are coinduced by the individual cytokines alone, as well as the induction of more than 850 novel host cell genes. This synergy is mediated directly by the two ligands, not by intermediate secreted factors, and is necessary and sufficient to completely block the productive replication and spread of myxoma virus in human fibroblasts. In contrast, the replication of two other poxviruses, vaccinia virus and tanapox virus, are only partially inhibited in these cells by the synergistic antiviral state, whereas the spread of both of these viruses to neighboring cells was efficiently blocked. Taken together, our data indicate that the combination of TNF and IFN-β induces a novel synergistic antiviral state that is highly distinct from that induced by either cytokine alone.

scholarly journals Interaction of human TNF and β2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L

Virology ◽  
2009 ◽  
Vol 386 (2) ◽  
pp. 462-468 ◽  
Author(s):  
Masmudur M. Rahman ◽  
David Jeng ◽  
Rajkumari Singh ◽  
Jake Coughlin ◽  
Karim Essani ◽  
...  
Keyword(s):  
Tnf Inhibitor ◽  
Β2 Microglobulin ◽  
Tanapox Virus

scholarly journals Tanapox. A serological survey of the lower Tana River valley

1979 ◽  
Vol 83 (2) ◽  
pp. 273-276 ◽  
Author(s):  
J. S. Axford ◽  
A. W. Downie
Keyword(s):  
Indigenous Population ◽  
Neutralizing Antibody ◽  
River Valley ◽  
Serological Survey ◽  
Virus Antibody ◽  
Tanapox Virus ◽  
Tana River

summarySera collected from the indigenous population of the Tana River valley during the Tana River Expedition in 1976 were examined for neutralizing antibody to Tanapox virus. Antibody was found in 9·2% of the population in infected areas. This result and the presence of antibody in four children indicated that infection had continued to occur in the area since the 1962 outbreak.

Tanapox Virus Infection

2002 ◽  
Vol 1 (6) ◽  
pp. 156-157 ◽  
Author(s):  
Anca G. Croitoru ◽  
Miriam B. Birge ◽  
Donald Rudikoff ◽  
Mei-Heng Tan ◽  
Robert G. Phelps
Keyword(s):  
Virus Infection ◽  
Tanapox Virus

scholarly journals Comparative genetic analysis of genomic DNA sequences of two human isolates of Tanapox virus

2007 ◽  
Vol 129 (1) ◽  
pp. 11-25 ◽  
Author(s):  
Steven H. Nazarian ◽  
John W. Barrett ◽  
A. Michael Frace ◽  
Melissa Olsen-Rasmussen ◽  
Marina Khristova ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Dna Sequences ◽  
Genomic Dna ◽  
Tanapox Virus ◽  
Comparative Genetic Analysis
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