Case 25: An abnormal mammogram

2009 ◽  
pp. 107-109
Keyword(s):  
Abnormal Mammogram

scholarly journals Time to Clinical Follow-up after Abnormal Mammogram among African American and Hispanic Women

2018 ◽  
Vol 29 (1) ◽  
pp. 448-462 ◽  
Author(s):  
Shariska S. Petersen ◽  
Marianna Sarkissyan ◽  
Yanyuan Wu ◽  
Sheila Clayton ◽  
Jaydutt V. Vadgama
Keyword(s):  
African American ◽  
Hispanic Women ◽  
Abnormal Mammogram

The Women’s Health Initiative randomized trial of calcium plus vitamin D: Effects on breast cancer and arthralgias

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. LBA6-LBA6 ◽  
Author(s):  
R. T. Chlebowski ◽  
K. C. Johnson ◽  
C. Kooperberg ◽  
A. Hubbell ◽  
D. Lane ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Postmenopausal Women ◽  
Breast Cancer Incidence ◽  
Secondary Outcome ◽  
Baseline Serum ◽  
Abnormal Mammogram ◽  
Joint Symptoms

LBA6 Background: Calcium (Ca) and vitamin D (D) have been associated with reduced breast cancer and breast density in observational studies. Randomized trials have not evaluated Ca/D supplementation for breast cancer prevention. Methods: We randomized 36,282 postmenopausal women without prior breast cancer from 40 WHI centers to 1000 mg of elemental calcium as calcium carbonate and 400 IU of vitamin D3 (N = 18,176) daily or matching placebo (N = 18,106); 54% were also randomized one year previously to hormone therapy (HT) or placebo; conjugated equine estrogen (CEE) plus medroxyprogesterone acetate or CEE alone (the latter for those with prior hysterectomy). Ca/D effects on hip fracture and colorectal cancer have been reported (NEJM 2006). We report here pathologically confirmed invasive breast cancer as a secondary outcome of the Ca/D trial. Baseline serum 25(OH) D levels (in 1787 women) and serial joint symptoms (pain/stiffness and hand/feet swelling 0–3 scale, in a 6% sample) were also assessed. Results: Breast cancer incidence did not differ between Ca/D and placebo randomization groups (528 and 546 cases in Ca/D and placebo; hazard ratio 0.96; 95 percent confidence interval (CI), 0.85, 1.09). While SEER stage and abnormal mammogram frequency were similar between groups, breast cancers were smaller in the Ca/D group (1.54 cm (1.23), mean (SD) versus 1.71 (1.29), P = 0.05). Total vitamin D baseline intake was associated with lower breast cancer risk in the placebo group. Baseline vitamin D (nmol per liter) deficiency was common (≥30, sufficient (n = 266), 16 ≤ 30, insufficient (277), < 16, deficient (743)) but was not related to joint pain (seen in 72.2%, 74.0%, 74.6%, of sufficiency and deficiency groups, respectively). Joint symptoms were lower in women randomized to CEE alone (P < 0.01) but did not significantly differ by Ca/D group assignment and no significant interactions were seen between HT and Ca/D. Conclusion: Among healthy postmenopausal women, Ca/D supplementation did not reduce breast cancer risk but the cancers in those randomized to Ca/D were somewhat smaller. Exogenous estrogen use but not Ca/D supplementation influences arthralgias. [Table: see text]

scholarly journals Ethnic differences in social support after initial receipt of an abnormal mammogram.

2016 ◽  
Vol 22 (4) ◽  
pp. 588-593 ◽  
Author(s):  
Yamile Molina ◽  
Sarah D. Hohl ◽  
Michelle Nguyen ◽  
Bridgette H. Hempstead ◽  
Shauna Rae Weatherby ◽  
...  
Keyword(s):  
Social Support ◽  
Ethnic Differences ◽  
Abnormal Mammogram

scholarly journals Breast tumor segmentation in mammography image via Chan-Vese technique

2021 ◽  
Vol 22 (2) ◽  
pp. 809
Author(s):  
Mohammed Y. Kamil ◽  
Eman A. Radhi
Keyword(s):  
High Efficiency ◽  
Noise Suppression ◽  
Low Frequency ◽  
Surrounding Tissue ◽  
Tumor Segmentation ◽  
Proposed Model ◽  
Abnormal Mammogram ◽  
Frequency Components ◽  
Mammography Image ◽  
Mammogram Images

The accurate segmentation of tumours is a crucial stage of diagnosis and treatment, reducing the damage that breast cancer causes, which is the most common type of cancer among women, especially after the age of forty. The task of segmenting breast tumours in mammograms is very difficult, as its difficulty lies in the lack of contrast between the tumour and the surrounding breast tissue, especially when dealing with small tumours that are not clear boundaries and hidden under the tissues. As algorithms often lose an automatic path toward the boundaries of the tumour at try to determine the site of this type of tumour. The study aims to create a clear contrast between the tumour and the healthy breast area. For this purpose, we used a Gaussian filter as a pre-processing as it works to intensify the low-frequency components while reducing the high-frequency components as the breast structure is enhanced and noise suppression. Then, CLAHE was used to improve the contrast of the image, which increases the contrast between the tumour and the surrounding tissue and sharpens the edges of the tumour. Next, the tumour was segmented by using the Chan-Vese method with appropriate parameters defined. The proposed method was applied to all abnormal mammogram images taken from a publicly available mini-MIAS database. The proposed model was tested in two ways, the first is statistical that got results (90.1, 94.8, 95.5, 92.1, 99.5) for Jaccard, Dice, PF-Score, precision, and sensitivity respectively. And the other is based on the segmented region's characteristics that results showed the algorithm could identify the tumour with high efficiency.

ABNORMAL MAMMOGRAM AS THE PRESENTING SIGN OF RENAL CELL CARCINOMA

2000 ◽  
pp. 1239
Author(s):  
DAVID J. GROSSKLAUS ◽  
JEFFREY M. HOLZBEIERLEIN ◽  
BRUCE J. ROTH ◽  
JOSEPH A. SMITH
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Abnormal Mammogram

Access to care and patient satisfaction for surgically-treated breast cancer

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17010-17010
Author(s):  
G. A. Porter ◽  
J. M. Murdoch ◽  
K. M. Inglis ◽  
P. J. Veugelers
Keyword(s):  
Breast Cancer ◽  
Patient Satisfaction ◽  
Short Interval ◽  
Time Interval ◽  
Specific Time ◽  
Time Intervals ◽  
Satisfaction Questionnaire ◽  
Younger Women ◽  
Natural Logarithm ◽  
Abnormal Mammogram

17010 Background: Although recent studies have described timeliness of breast cancer (BC) care and its impact on outcomes, there is little data on patient perception of timeliness. This study examined the association between clinicodemographic factors, timeliness and patient satisfaction for surgically-treated BC patients across defined intervals of diagnosis (Dx) and treatment. Methods: All patients undergoing surgery for primary BC within a single Health District over 24 months were enrolled in a prospective consecutive cohort study. A comprehensive, standardized method of ascertaining specific time intervals, including a patient interview, was used to quantify the timeliness of presentation, Dx and treatment. A validated satisfaction questionnaire was applied to patients 2 weeks after surgery, and following chemotherapy. Multiple linear regression, using the natural logarithm of the time interval as the dependant variable, was performed to examine the association of factors and satisfaction with specific time intervals. Results: Among the 519 patients in the study, 317 (61%) were screen-detected and 202 (39%) presented symptomatically. Complete satisfaction questionnaire responses were obtained in 348 (67%). The median time intervals in days (interquartile range) were: abnormal screen to Dx - 33 (21–48); symptoms to Dx 44 (23–97); Dx to surgery - 31 (22–43); surgery to adjuvant chemotherapy 63 (49–73). On multivariate analysis, the interval from presentation (either abnormal mammogram or symptoms) to Dx was 33% longer for screen-detected patients (p<0.0001) and 38% longer for patients where more than one diagnostic test was performed (p=0.009). Moderate correlation was identified between patient satisfaction and both the intervals from presentation to Dx (r2=0.212;p<0.0001) and from Dx to surgery (r2=0.262;p<0.0001). Controlling for the length of these intervals, younger women (p=0.01) and those with a Dx made via screening (p=0.004) had significantly lower satisfaction scores. Conclusions: The timeliness of care for BC involves several defined components; variations in the relatively short interval from Dx to surgery appeared to have most impact on patient satisfaction. Younger women and those diagnosed via screening were less satisfied with their access to timely care. No significant financial relationships to disclose.

Correlation between preoperative T1 breast cancer staging and final pathologic analysis.

2011 ◽  
Vol 29 (27_suppl) ◽  
pp. 101-101
Author(s):  
J. S. Gass ◽  
D. L. Wiggins ◽  
D. S. Dizon
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
New Technologies ◽  
Preoperative Evaluation ◽  
Radiographic Evaluation ◽  
Breast Cancers ◽  
Core Needle ◽  
Final Pathology ◽  
Abnormal Mammogram

101 Background: Contemporary breast surgery is exploring less invasive techniques for the treatment of breast cancer and recent approaches such as ablative therapy have shown promise in early trials. Caution is required prior to adopting of these techniques, however, as ablative treatment may hinder interpretation of final pathology, which might impact adjuvant recommendations. To address this concern, we evaluated the concordance between preoperative core needle biopsy and postoperative final pathology, to determine whether the biopsy findings predicted final pathology. Methods: A retrospective chart review was performed of women diagnosed with breast cancers less than 2 cm on radiographic evaluation between 1997 and 2004. Concordance between preoperative assessment (by imaging and core needle biopsy) and final pathology results was analyzed based on tumor size, grade, lymphovascular space invasion, and in situ component. Kappa analysis was performed to characterize agreement. Results: We identified 56 women from our institution for analysis. The median age was 56 (range, 38-94) and the majority had presented with an abnormal mammogram (61%). The vast majority also underwent breast-conserving surgery (95%). Agreement was moderately accurate between preoperative and final assessment of grade (weighted κ 0.536) and size (weighted κ 0.464). It was not accurate in the assessment of lymphovascular invasion (weighted κ 0.123) and the presence of DCIS (weighted κ 0.197). Conclusions: Information from preoperative evaluation is insufficiently accurate for the evaluation of breast tumors, which may be important for adjuvant decision making. This information must be taken in to account when assessing new technologies, which may impact on the assessment of histologic criteria in excised breast cancers.

Abstract B82: Time to clinical follow up after abnormal mammogram in African American and Hispanic women: Preliminary findings.

2012 ◽  
Author(s):  
Shariska S. Petersen ◽  
Marianna Sarkissyan ◽  
Yanyuan Wu ◽  
Marianne Carlota ◽  
Jaydutt V. Vadgama
Keyword(s):  
African American ◽  
Hispanic Women ◽  
Abnormal Mammogram
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